Bolus stimulation in a neurostimulation device particularly useful in providing sub-perception stimulation
View Patent ↗A method and external device for providing sub-perception stimulation to a patient via an implantable stimulator device is disclosed. Stimulation parameters for the patient are determined that provide sub-perception stimulation to address a symptom of the patient. A schedule is determined to provide scheduled boluses of stimulation, where each bolus comprises a duration during which stimulation is applied to the patient in accordance with the stimulation parameters, and where the scheduled boluses are separated by off times when no stimulation is provided to the patient. Preferably, the duration of each of the scheduled boluses is 3 minutes or longer, and the duration of each of the off times is 30 minutes or greater. Additional boluses can be provided on demand in addition to the scheduled boluses by selecting an option on the external device, although the provision of such additional boluses may be constrained by a lockout period.
1. A method for providing stimulation to a patient using an implantable stimulator device and an external device in communication with the implantable stimulator device, comprising:
determining stimulation parameters for the patient to address a symptom of the patient;
providing a first option on a graphical user interface of the external device to schedule scheduled boluses of stimulation for the patient, wherein each scheduled bolus comprises a first duration during which stimulation is applied to the patient in accordance with the stimulation parameters, wherein the scheduled boluses are separated by off times of a second duration when no stimulation is provided to the patient;
providing a second option on the graphical user interface of the external device to receive from the patient at a first time an input to immediately provide an additional unscheduled bolus of stimulation in accordance with the stimulation parameters; and
providing, using the implantable stimulator device, at least the scheduled boluses to neural tissue of the patient according to the schedule.
2. The method of claim 1 , wherein the stimulation parameters provide sub-perception stimulation to address a symptom of the patient.
3. The method of claim 1 , wherein the neural tissue comprises a spinal cord of the patient.
4. The method of claim 1 , wherein the first duration of each of the scheduled boluses is 3 minutes or longer, and wherein the second duration of each of the off times is 30 minutes or greater.
5. The method of claim 1 , wherein the stimulation provided during each scheduled bolus comprises a sequence of periodic pulses.
6. The method of claim 5 , wherein the stimulation parameters comprise one or more of an amplitude of the pulses, a pulse width of the pulses, or a frequency of the pulses.
7. The method of claim 6 , wherein the frequency is 10 kHz or less.
8. The method of claim 6 , wherein the frequency is 1 kHz or less.
9. The method of claim 6 , wherein the amplitude comprises a constant current amplitude.
10. The method of claim 1 , wherein the first durations of the scheduled boluses vary.
11. The method of claim 1 , wherein the second durations of the off times vary.
12. The method of claim 1 , further comprising determining an activity of the patient.
13. The method of claim 12 , wherein either or both of the first durations of the scheduled boluses or the second durations of the off times are adjusted in accordance with the determined activity.
14. The method of claim 12 , wherein the stimulation parameters are determined in accordance with the determined activity.
15. The method of claim 12 , wherein the activity of the patient is determined using an activity sensor.
16. The method of claim 15 , wherein the activity sensor is within the implantable stimulator device.
17. The method of claim 1 , wherein the stimulation parameters are determined at the external device, and wherein the schedule is determined at the external device.
18. The method of claim 1 , further comprising immediately providing the additional unscheduled bolus to the neural tissue in addition to providing the scheduled boluses.
19. The method of claim 1 , wherein the graphical user interface is programmed with a lockout period, further comprising immediately providing the additional unscheduled bolus of stimulation to the neural tissue only if a third duration between the first time and a preceding one of the scheduled boluses is equal to or longer than the lockout period.
20. The method of claim 19 , further comprising rescheduling at least one of the scheduled boluses after the additional unscheduled bolus in accordance with the lockout period.