IP Library Granted Patent US 12,064,572
Granted Patent B2
US 12,064,572 · App. 15/545,309 · Granted Aug 20, 2024

Tubular structures with variable support

Inventors: Jeffery Krolik (Campbell, CA); Rajan Khokhar (Santa Cruz, CA)
Assignee: Q'APEL MEDICAL, INC.
A61M25/0155A61F2/915A61M25/0053A61M25/10A61M29/02A61F2002/825A61F2002/91575A61M25/0023A61M2025/0024A61M25/0054A61M25/0108A61M25/0122A61M2025/1043A61M2207/00
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Quick Facts
Patent No.
US 12,064,572
App. No.
15/545,309
Granted
Aug 20, 2024
Kind
B2
Abstract

A tubular structure having variable support includes a tubular member and a structural support member with a flexible tubular member over the structural support member, such that the flexible tubular member can engage and disengage or squeeze and release the structural support member. The structural support member can be a tubular mesh, stent, framework, skeleton, braid or other flexible framework. A fluid passage can be used to inflate and deflate the flexible tubular member. Methods of assembly and methods of use are also described.

Claims (27)

1. A flexible lumenal assembly configured for transiting a body lumen comprising a flexible lumenal member extending longitudinally, a monolithic structural support member extending outside a portion of the flexible lumenal member configured to contact the flexible lumenal member differently as a function of pressure applied to the structural support member and wherein the monolithic structural support member is substantially inextensible, and an outer member over the structural support member wherein the outer member is configured to selectively apply pressure to the structural support member.

2. The assembly of claim 1 wherein the structural support member is a tubular mesh.

3. The assembly of claim 2 wherein the tubular mesh includes a non-random tubular mesh.

4. The assembly of claim 1 further including a passageway for fluid to enter and exit an area between the structural support member and the outer member.

5. The assembly of claim 1 wherein the outer member is resiliently flexible.

6. The assembly of claim 1 wherein the outer member is a balloon.

7. The assembly of claim 1 wherein the outer member is configured to have an enlarged configuration and a reduced configuration, and wherein in the reduced configuration the outer member applies pressure to the structural support member.

8. The assembly of claim 7 wherein the assembly is configured such that enlargement of the outer member relieves at least part of the pressure on the structural support member.

9. The assembly of claim 8 wherein the assembly is configured such that enlargement of the outer member relieves all of the pressure on the structural support member.

10. The assembly of claim 9 wherein the assembly is configured such that relieving pressure on the structural support member includes reducing a surface area of contact between the outer member and the structural support member.

11. The assembly of claim 1 wherein the structural support member is a stent.

12. The assembly of claim 1 wherein the assembly forms a portion of a catheter.

13. The assembly of claim 1 configured to receive a dilator element.

14. The assembly of claim 1 configured to receive a syringe.

15. A flexible lumenal assembly configured for transiting a body lumen comprising a lumenal element extending longitudinally, a monolithic tubular mesh extending longitudinally and circumferentially around a portion of the lumenal element and configured to contact the lumenal element differently as a function of pressure applied to the tubular mesh, and a tubular member at least partly sealed to the lumenal element and wherein all portions of the tubular mesh are positioned between a respective surface of the lumenal element where the lumenal element is configured to resist deformation from compressive loading due to the tubular member and a respective surface of the tubular member, and wherein the assembly is configured to have a first stiffness when the tubular member is enlarged less than a stiffness when the tubular member is not enlarged and contacting the monolithic tubular mesh.

16. The assembly of claim 15 wherein the tubular member is configured to be biased for pressing against the tubular mesh.

17. The assembly of claim 15 wherein the tubular member is sufficiently flexible to have surface portions extend between individual components of the tubular mesh.

18. The assembly of claim 15 wherein the tubular mesh is configured in the assembly to have an inside diameter substantially the same as an outside diameter of the adjacent lumenal element.

19. The assembly of claim 15 wherein the tubular mesh includes a plurality of component elements and wherein a plurality of the component elements include longitudinally extending component elements when the lumenal element extends substantially straight.

20. The assembly of claim 19 wherein a first plurality of longitudinally extending component elements extends circumferentially around the tubular mesh and another plurality of longitudinally extending elements extends circumferentially around the tubular mesh and shifted longitudinally from the first plurality of longitudinally extending elements.

21. The assembly of claim 15 wherein the tubular mesh is a stent.

22. The assembly of claim 15 wherein the lumenal element is a cylindrical tubular element.

23. The assembly of claim 15 wherein the lumenal member is configured for receiving a guidewire.

24. The assembly of claim 15 further including a lumen for receiving a fluid configured to allow the fluid to enter a space occupied by the tubular mesh between the tubular element and the lumenal element.

25. A flexible lumenal assembly configured for transiting a body lumen comprising a flexible lumenal member extending longitudinally and a monolithic structural support member extending longitudinally outside a portion of the flexible lumenal member, wherein the monolithic structural support member is substantially inextensible, and an outer member over the structural support member and wherein the outer member is configured to selectively apply pressure to the structural support member by enlargement and contraction and the monolithic structural support member is configured to contact the flexible lumenal member with a lower pressure when the outer member is enlarged than when the outer member is contracted.

26. The assembly of claim 25 wherein the structural support member includes a plurality of interconnected struts wherein the plurality of interconnected struts each have a wall thickness in a radial direction relative to the body lumen between respective inside and outside surfaces wherein the wall thicknesses are substantially constant.

27. The assembly of claim 25 wherein the structural support member is a non-random structural support member.

Assignments (12)
RELEASE OF SECURITY INTEREST Recorded Jul 2, 2026
From: MIDCAP FINANCIAL TRUST
To: Q'APEL MEDICAL, INC.
Reel/Frame 075163/0507 →
RELEASE OF SECURITY INTEREST Recorded Jul 2, 2026
From: MIDCAP FUNDING IV TRUST
To: Q'APEL MEDICAL, INC.
Reel/Frame 075163/0838 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 2, 2026
From: Q'APEL MEDICAL, INC.
To: TRINITY CAPITAL INC.
Reel/Frame 075901/0428 →
RELEASE OF SECURITY INTEREST Recorded Jul 2, 2026
From: MIDCAP FINANCIAL TRUST
To: Q'APEL MEDICAL, INC.
Reel/Frame 075163/0326 →
RELEASE OF SECURITY INTEREST Recorded Jul 2, 2026
From: MIDCAP FUNDING IV TRUST
To: Q'APEL MEDICAL, INC.
Reel/Frame 075163/0666 →
SECURITY INTEREST Recorded Dec 9, 2024
From: Q’APEL MEDICAL, INC.
To: MIDCAP FINANCIAL TRUST
Reel/Frame 069526/0827 →
SECURITY INTEREST Recorded Dec 9, 2024
From: Q’APEL MEDICAL, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 069526/0876 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2024
From: KROLIK, JEFFERY
To: Q'APEL MEDICAL, LLC
Reel/Frame 067094/0370 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2024
From: KHOKHAR, RAJAN
To: Q'APEL MEDICAL, LLC
Reel/Frame 067094/0422 →
SECURITY INTEREST (REVOLVING) Recorded Aug 18, 2022
From: Q'APEL MEDICAL, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 061207/0766 →
SECURITY INTEREST (TERM) Recorded Aug 18, 2022
From: Q'APEL MEDICAL, INC.
To: MIDCAP FINANCIAL TRUST
Reel/Frame 061207/0756 →
CHANGE OF NAME Recorded Aug 8, 2022
From: Q'APEL MEDICAL, LLC
To: Q'APEL MEDICAL, INC.
Reel/Frame 061118/0693 →
Continuity (3)
Provisional Application 62125294 · Jan 20, 2015
Provisional Application 62196902 · Jul 24, 2015
Related Publication 20180015257A1 · Jan 18, 2018