IP Library › Granted Patent US 12,100,493
Granted Patent B2
US 12,100,493 · App. 17/404,015 · Granted Sep 24, 2024

Lung analysis and reporting system

Inventor: Nathaniel C. Culala (Bothell, WA)
Assignee: Gyrus ACMI, Inc.
G16H15/00G06T7/0012G06T11/001G16H20/40G16H30/40A61B6/50G06T2207/30061
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Quick Facts
Patent No.
US 12,100,493
App. No.
17/404,015
Granted
Sep 24, 2024
Kind
B2
Abstract

A system and method for analyzing scan data of a lung and presenting a lung candidacy report. The lung candidacy report includes determinations represented visually of whether lung lobes are suitable candidates for a bronchoscopy guided lung volume reduction procedure. The lung candidacy report includes emphysema values and fissure integrity determined from the scan data.

Claims (61)

1. A method comprising:

receiving three-dimensional scan data of at least a portion of a lung of a person, the three-dimensional scan data comprises voxels;

delineating lung lobes and lung fissures from the voxels;

generating emphysema scores for individual ones of the lung lobes based on a predefined threshold of radio density values or a threshold range of radio density values;

generating fissure integrity scores for individual ones of the lung fissures based on the voxels; and

generating heterogeneity scores for at least two lobes based on the emphysema score of a target lobe and the emphysema score of a lobe adjacent to the target lobe; and

outputting a report that comprises:

a plurality of visual representations of individual ones of the lung lobes; and

a plurality of lung lobe candidacy icons that are visually individually associated with individual ones of the plurality of visual representations, wherein individual ones of the lung lobe candidacy icons comprise a visual indication of meeting a predefined inclusion criterion for the emphysema scores, the fissure integrity scores, and the heterogeneity scores, the visual indication of meeting the predefined inclusion criteria comprises representing at least a portion of the lung lobe candidacy icon in at least one of a unique color or pattern.

2. The method of claim 1 , wherein the radio density values are represented in Hounsfield unit values.

3. The method of claim 1 , further comprising performing a bronchoscopic lung volume reduction procedure on the person based on the outputted report.

4. The method of claim 1 , wherein the report further comprises:

a plurality of visual representations of an emphysema level based on the generated emphysema scores, the visual representations of the emphysema level are visually represented by a least one of a particular color or pattern within visual representations of individual ones of the lung lobes; and

a visual representation of fissure integrity based on the generated fissure integrity scores, the visual representation of the fissure integrity comprising a visual representation of each of the delineated fissures, wherein the delineated fissures are visually represented by a least one of a particular color or pattern based on the fissure integrity score.

5. The method of claim 1 , wherein the lung lobe candidacy icons comprise the emphysema score and the heterogeneity score of the associated lung lobe and the fissure integrity score of the fissure adjacent to the associated lung lobe.

6. The method of claim 5 , wherein the emphysema scores, the fissure integrity scores, and the heterogeneity scores are represented as numerical values.

7. The method of claim 5 , wherein the lung lobe candidacy icons further comprise:

an emphysema score identifier located adjacent to the respective emphysema score;

a fissure integrity score identifier located adjacent to the respective fissure integrity score; and

a heterogeneity score identifier located adjacent to the respective heterogeneity score.

8. A system comprising:

a processing device configured to:

receive three-dimensional scan data of at least a portion of a lung of a person, the three-dimensional scan data comprises voxels;

delineate lung lobes and lung fissures from the voxels;

generate emphysema scores for individual ones of the lung lobes based on a predefined threshold of radio density values or a threshold range of radio density values;

generate fissure integrity scores for individual ones of the lung fissures based on the voxels; and

generate heterogeneity scores for at least two lobes based on the emphysema score of a target lobe and the emphysema score of a lobe adjacent to the target lobe; and

an output device is in signal communication with the processing device, the output device is configured to output the report, wherein the report comprises:

a plurality of visual representations of individual ones of the lung lobes, wherein the emphysema level is visually represented by a least one of a particular color or pattern of a corresponding lung lobe visual representation; and

a plurality of lung lobe candidacy icons that are visually individually associated with individual ones of the plurality of visual representations, wherein individual ones of the lung lobe candidacy icons comprise a visual indication of meeting a predefined inclusion criterion for the emphysema scores, the fissure integrity scores, and the heterogeneity scores, the visual indication of meeting the predefined inclusion criteria comprises representing at least a portion of the lung lobe candidacy icon in at least one of a unique color or pattern.

9. The system of claim 8 , wherein the report further comprises:

a plurality of visual representations of an emphysema level based on the generated emphysema scores, the visual representations of the emphysema level are visually represented by a least one of a particular color or pattern within the visual representations of individual ones of the lung lobes.

10. The system of claim 8 , wherein the report further comprises:

a visual representation of fissure integrity based on the generated fissure integrity scores, the visual representation of the fissure integrity comprising a visual representation of each of the delineated fissures, wherein the delineated fissures are visually represented by a least one of a particular color or pattern based on the fissure integrity score.

11. The system of claim 8 , wherein the lung lobe candidacy icons comprise the emphysema score and the heterogeneity score of the associated lung lobe and the fissure integrity score of the fissure adjacent to the associated lung lobe.

12. The system of claim 11 , wherein the emphysema scores, the fissure integrity scores, and the heterogeneity scores are represented as numerical values.

13. The system of claim 11 , wherein the lung lobe candidacy icons further comprise:

an emphysema score identifier located adjacent to the respective emphysema score;

a fissure integrity score identifier located adjacent to the respective fissure integrity score; and

a heterogeneity score identifier located adjacent to the respective heterogeneity score.

14. The system of claim 8 , wherein the radio density values are represented in Hounsfield unit values.

15. A non-transitory computer-readable recording medium with an executable program stored thereon, the program causing a processor to:

receive three-dimensional scan data of at least a portion of a lung of a person, the three-dimensional scan data comprises voxels;

delineate lung lobes and lung fissures from the voxels;

generate emphysema scores for individual ones of the lung lobes based on a predefined threshold of radio density values or a threshold range of radio density values;

generate fissure integrity scores for individual ones of the lung fissures based on the voxels;

generate heterogeneity scores for at least two lobes based on the emphysema score of a target lobe and the emphysema score of a lobe adjacent to the target lobe; and

output a report to an output device,

wherein the report comprises:

a plurality of visual representations of individual ones of the lung lobes; and

a plurality of lung lobe candidacy icons that are visually individually associated with individual ones of the plurality of visual representations, wherein individual ones of the lung lobe candidacy icons comprise a visual indication of meeting a predefined inclusion criterion for the emphysema scores, the fissure integrity scores, and the heterogeneity scores, the visual indication of meeting the predefined inclusion criteria comprises representing at least a portion of the lung lobe candidacy icon in at least one of a unique color or pattern.

16. The non-transitory computer-readable recording medium of claim 15 , wherein the report further comprises:

a plurality of visual representations of an emphysema level based on the generated emphysema scores, the visual representations of the emphysema level are visually represented by a least one of a particular color or pattern within the visual representations of individual ones of the lung lobes; and

a visual representation of fissure integrity based on the generated fissure integrity scores, the visual representation of the fissure integrity comprising a visual representation of each of the delineated fissures, wherein the delineated fissures are visually represented by a least one of a particular color or pattern based on the fissure integrity score.

17. The non-transitory computer-readable recording medium of claim 15 , wherein the lung lobe candidacy icons comprise the emphysema score and the heterogeneity score of the associated lung lobe and the fissure integrity score of the fissure adjacent to the associated lung lobe.

18. The non-transitory computer-readable recording medium of claim 17 , wherein the emphysema scores, the fissure integrity scores, and the heterogeneity scores are represented as numerical values.

19. The non-transitory computer-readable recording medium of claim 17 , wherein the lung lobe candidacy icons further comprise:

an emphysema score identifier located adjacent to the respective emphysema score;

a fissure integrity score identifier located adjacent to the respective fissure integrity score; and

a heterogeneity score identifier located adjacent to the respective heterogeneity score.

20. The non-transitory computer-readable recording medium of claim 15 , wherein the radio density values are represented in Hounsfield unit values.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 17, 2021
From: CULALA, NATHANIEL C.
To: GYRUS ACMI, INC. D/B/A OLYMPUS SURGICAL TECHNOLOGIES AMERICA
Reel/Frame 057198/0497 →
Continuity (3)
Continuation In Part 16288642 · Feb 28, 2019
Provisional Application 62792706 · Jan 15, 2019
Related Publication 20220036985A1 · Feb 3, 2022
Cited By (1)
US 12,711,618