Animal treatment apparatus, phototherapeutic apparatus, and animal treatment method
A method of treating a non-human animal subject includes irradiating, one or more times, light having a peak wavelength in a range of 315-335 nm to an affected area of the animal subject.
1. A method of treating a non-human animal subject, comprising:
performing a first step comprising irradiating an affected area of skin of the non-human animal subject with light having a first peak wavelength, which is in a range of 315-335 nm at a first irradiation dose; and
one or more days after the first step, performing a second step comprising irradiating the affected area of the skin with light having a second peak wavelength in the range of 315-335 nm at a second irradiation dose, wherein the second peak wavelength is shorter than the first peak wavelength.
2. The method according to claim 1 , wherein:
the first peak wavelength is in a range of 325-335 nm, and
the second peak wavelength is in a range of 315-325 nm.
3. The method according to claim 1 , wherein the light irradiated in the first and second steps has a relative illuminance at wavelengths less than 315 nm of 30% or less.
4. The method according to claim 1 , wherein the method is used to treat a disease or disorder mediated by MrgprX2 gene.
5. The method according to claim 1 , wherein the method is used to treat a disease or disorder selected from the group consisting of allergic dermatitis, cutaneous lymphoma, vitiligo, a wound, alopecia, an infectious disease, a skin abscess, and pyoderma.
6. The method according to claim 1 , wherein the first step further comprises irradiating the affected area with the light having the first peak wavelength at a third irradiation dose that is higher than the first irradiation dose.
7. The method according to claim 6 , wherein:
the first irradiation dose is 300 mJ/cm 2 or less, and
the third irradiation dose is more than 300 mJ/cm 2 but less than an irradiation dose that would cause sunburn to the skin.
8. The method according to claim 6 , wherein the first step further comprises repeating the step defined in claim 6 , with the third irradiation dose increasing each repetition.
9. The method according to claim 1 , wherein the second step further comprises irradiating the affected area with the light having the second peak wavelength at a fourth irradiation dose that is higher than the second irradiation dose.
10. The method according to claim 9 , wherein the second step further comprises repeating the step defined in claim 8 , with the fourth irradiation dose increasing each repetition.
11. The method according to claim 1 , further comprising performing a third step comprising irradiating the affected area with light having a third peak wavelength in a range of 305-315 nm at a fifth irradiation dose.
12. The method according to claim 11 , wherein the third step further comprises irradiating the affected area with the light having the third peak wavelength at a sixth irradiation dose that is higher than the fifth irradiation dose.
13. The method according to claim 12 , wherein the third step further comprises repeating the step defined in claim 11 , with the sixth dose increasing each repetition.
14. The method according to claim 11 , wherein the fifth irradiation dose is 300 mJ/cm 2 or less.
15. The method according to claim 1 , wherein the light having a peak wavelength in the range of 315-335 nm is emitted by a light emitting diode (LED) or laser diode (LD).