Oxysterols and methods of use thereof
Compounds are provided according to Formula (A): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R G are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.
1. A compound selected from the group consisting of:
2. A pharmaceutical composition comprising a compound of claim 1 , and a pharmaceutically acceptable carrier.
3. The compound of claim 1 , wherein the compound is selected from the group consisting of:
4. The compound of claim 1 , wherein the compound is selected from the group consisting of:
5. A pharmaceutically acceptable salt of a compound selected from the group consisting of:
6. The pharmaceutically acceptable salt of claim 5 , wherein the compound is selected from the group consisting of:
7. The pharmaceutically acceptable salt of claim 5 , wherein the compound is selected from the group consisting of:
8. A pharmaceutical composition comprising a compound of claim 3 , and a pharmaceutically acceptable carrier.
9. A pharmaceutical composition comprising a compound of claim 4 , and a pharmaceutically acceptable carrier.
10. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 5 , and a pharmaceutically acceptable carrier.
11. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 6 , and a pharmaceutically acceptable carrier.
12. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 7 , and a pharmaceutically acceptable carrier.