IP Library › Granted Patent US 12,180,321
Granted Patent B2
US 12,180,321 · App. 17/605,415 · Granted Dec 31, 2024

Monomer composition for contact lenses, polymer for contact lenses and method for producing same, and contact lens and method for producing the same

Inventors: Shu Takashima (Kawasaki, JP); Koh Kobayashi (Kawasaki, JP); Ryuya Gotanda (Kawasaki, JP); Norio Iwakiri (Kawasaki, JP); Yosuke Matsuoka (Kawasaki, JP); Eiji Harata (Kawasaki, JP)
Assignee: NOF CORPORATION
C08F290/068C08G77/395G02B1/043G02C7/04
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Quick Facts
Patent No.
US 12,180,321
App. No.
17/605,415
Granted
Dec 31, 2024
Kind
B2
Abstract

Provided is a monomer composition for contact lenses, which uses a polysiloxane monomer to produce a polymer that shows satisfactory surface hydrophilicity and oxygen permeability, and that is excellent in modulus and elongation at break. It has been found that a monomer composition containing a phosphorylcholine group-containing polysiloxane monomer, a monovinyl ether monomer, and the like can achieve the above-mentioned object.

Claims (25)

1. A monomer composition for contact lenses, comprising the following components:

(A) a phosphorylcholine group-containing polysiloxane monomer represented by the following formula (1);

(B) a phosphorylcholine group-containing methacrylic monomer represented by the following formula (2);

(C) a trimethylsiloxysilyl group-containing silicone monomer having at least one or more hydroxy groups in a molecule;

(D) a monovinyl ether monomer having at least one or more hydroxy groups in a molecule;

(E) one or more kinds of hydroxy group-containing monomers selected from: hydroxyethyl (meth)acrylate; hydroxypropyl (meth)acrylate; hydroxybutyl (meth)acrylate; and hydroxyethylacrylamide;

(F) a crosslinker; and

(G) a monomer other than the components (A) to (F),

wherein, with respect to 100 mass % in total of all monomer components in the composition, a content ratio of the component (A) is from 10 mass % to 50 mass %, a content ratio of the component (B) is from 5 mass % to 20 mass %, a content ratio of the component (C) is from 5 mass % to 40 mass %, a content ratio of the component (D) is from 5 mass % to 40 mass %, a content ratio of the component (E) is from 5 mass % to 30 mass %, a content ratio of the component (F) is from 0.1 mass % to 15 mass %, and a content ratio of the component (G) is from 0 mass % to 50 mass %:

in the formula (1), “a” represents an integer of from 20 to 500, “b” represents an integer of from 1 to 70, “c” represents 0 or 1, “p” and “q” each represent 0 or 1, and X represents —CH 2 — or —CH 2 CH 2 —,

2. The monomer composition for contact lenses according to claim 1 , further comprising a component (H) a solvent having a hydroxy group, wherein a content ratio of the component (H) is 30 parts by mass or less with respect to 100 parts by mass in total of all monomer components in the composition.

3. A polymer for contact lenses, comprising a polymer of the monomer composition for contact lenses of claim 1 .

4. A contact lens, comprising a hydrate of the polymer for contact lenses of claim 3 .

5. A method of producing a polymer for contact lenses, including a step of polymerizing the following monomer composition:

a composition including the following components:

(A) a phosphorylcholine group-containing polysiloxane monomer represented by the following formula (1);

(B) a phosphorylcholine group-containing methacrylic monomer represented by the following formula (2);

(C) a trimethylsiloxysilyl group-containing silicone monomer having at least one or more hydroxy groups in a molecule;

(D) a monovinyl ether monomer having at least one or more hydroxy groups in a molecule;

(E) one or more kinds of hydroxy group-containing monomers selected from: hydroxyethyl (meth)acrylate; hydroxypropyl (meth)acrylate; hydroxybutyl (meth)acrylate; and hydroxyethylacrylamide;

(F) a crosslinker; and

(G) a monomer other than the components (A) to (F),

wherein, with respect to 100 mass % in total of all monomer components in the composition, a content ratio of the component (A) is from 10 mass % to 50 mass %, a content ratio of the component (B) is from 5 mass % to 20 mass %, a content ratio of the component (C) is from 5 mass % to 40 mass %, a content ratio of the component (D) is from 5 mass % to 40 mass %, a content ratio of the component (E) is from 5 mass % to 30 mass %, a content ratio of the component (F) is from 0.1 mass % to 15 mass %, and a content ratio of the component (G) is from 0 mass % to 50 mass %:

in the formula (1), “a” represents an integer of from 20 to 500, “b” represents an integer of from 1 to 70, “c” represents 0 or 1, “p” and “q” each represent 0 or 1, and X represents —CH 2 — or —CH 2 CH 2 —,

6. The method of producing a polymer for contact lenses according to claim 5 , the composition further including a component (H) a solvent having a hydroxy group, wherein a content ratio of the component (H) is 30 parts by mass or less with respect to 100 parts by mass in total of all monomer components in the composition.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 21, 2021
From: TAKASHIMA, SHU; KOBAYASHI, KOH; GOTANDA, RYUYA; IWAKIRI, NORIO; MATSUOKA, YOSUKE; HARATA, EIJI
To: NOF CORPORATION
Reel/Frame 057867/0892 →
Priority Claims (1)
JP 2019-083615 · Apr 25, 2019 · national
Continuity (1)
Related Publication 20220227911A1 · Jul 21, 2022