IP Library Granted Patent US 12,191,017
Granted Patent B2
US 12,191,017 · App. 17/209,083 · Granted Jan 7, 2025

Systems and methods for medicine administration and tracking

Inventors: Michael R. Mensinger (San Diego, CA); Angela R. Gaetano (San Diego, CA); Madison B. Smith (San Diego, CA); Heung Y. Im (La Jolla, CA); Francis W. Pascual (San Diego, CA); Jasper Benke (San Diego, CA); Sneha Thanasekaran (San Diego, CA)
Assignee: Medtronic MiniMed, Inc.
G16H20/17A61M5/2033G16H40/67G16H50/30G16H50/70A61M2230/201
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Quick Facts
Patent No.
US 12,191,017
App. No.
17/209,083
Granted
Jan 7, 2025
Kind
B2
Abstract

A medicine administration and tracking system includes a delivery device configured to deliver a plurality of doses of medicine over a plurality of days and a computing device configured to receive dose information for each dose. The computing device includes a software application operable to cause the computing device to retrieve the dose information for all doses within a pre-determined period of days, categorize each dose within the pre-determined period of days into one of a plurality of time blocks throughout a 24-hour timeframe, determine a time of interest based on a time block of the plurality of time blocks having the least amount of doses categorized therein, and select a physiological parameter reading from a plurality of physiological parameter readings as a physiological parameter reading of interest based on a proximity of a time of the physiological parameter reading to the determined time of interest.

Claims (48)

1. A medicine administration and tracking system, comprising:

a medicine delivery device configured to deliver a plurality of doses of medicine to a user over a plurality of days, the medicine delivery device including:

a sensor that measures a dose of the medicine dispensed from the medicine delivery device, wherein the medicine delivery device administers the dose of the medicine to the user to thereby cause the sensor to measure the dose of the medicine administered to the user by the medicine delivery device; and

a processor configured to generate dose information associated with the dose of the medicine dispensed from the medicine delivery device as measured by the sensor and to wirelessly transmit, for each dose of the plurality of doses, dose information indicative of a time of delivery of the dose; and

a computing device in communication with the medicine delivery device and configured to receive the dose information for each dose of the plurality of doses, the computing device including a data processing unit including a processor and a software application stored in a memory of the data processing unit and having instructions operable, when executed by the processor, to cause the computing device to:

retrieve, from a signal wirelessly transmitted from the medicine delivery device to the computing device, the dose information for all doses of the plurality of doses within a pre-determined period of days;

categorize each dose of the plurality of doses within the pre-determined period of days into one of a plurality of time blocks throughout a 24-hour timeframe;

determine, based on a time block of the plurality of time blocks having the least amount of doses categorized therein, a fasting period end time of the user; and

select a physiological parameter reading from a plurality of physiological parameter readings as a physiological parameter reading of interest based on a proximity of a time of the physiological parameter reading to the determined fasting period end time of the user, wherein the medicine delivery device is used to administer an adjusted dose of the medicine to the user.

2. The medicine administration and tracking system according to claim 1 , further comprising: a sensor device configured to obtain the plurality of physiological parameter readings and to transmit the plurality of physiological parameter readings to the computing device.

3. The medicine administration and tracking system according to claim 1 , wherein the physiological parameter readings are a plurality of blood glucose readings and the physiological parameter reading of interest is a fasting blood glucose reading.

4. The medicine administration and tracking system according to claim 3 , further comprising:

a blood glucose sensor device configured to obtain the plurality of blood glucose readings and to transmit the plurality of blood glucose readings to the computing device.

5. The medicine administration and tracking system according to claim 4 , wherein the blood glucose sensor device is a continuous glucose monitor.

6. The medicine administration and tracking system according to claim 3 , wherein the instructions are further operable, when executed by the processor, to cause the computing device to:

determine a fasting period start time based on the fasting period end time; and

select a blood glucose reading from the plurality of blood glucose readings as a pre-fasting blood glucose reading based on a proximity of a time of the blood glucose reading to the fasting period start time.

7. The medicine administration and tracking system according to claim 6 , wherein the fasting period start time is a sleeping start time, the fasting period end time is a sleeping end time, and wherein a sleeping period is defined between the sleeping period start time and the sleeping period end time.

8. The medicine administration and tracking system according to claim 6 , wherein the instructions are further operable, when executed by the processor, to cause the computing device to:

determine whether a risk of hypoglycemia is too high; and

where it is determined that the risk of hypoglycemia is too high, calculate a dose amount decrease for adjusting a dose amount delivered by the medicine delivery device.

9. The medicine administration and tracking system according to claim 8 , wherein determining whether a risk of hypoglycemia is too high is based upon the pre-fasting blood glucose reading and the fasting blood glucose reading.

10. A method of medicine administration and tracking, comprising:

delivering a plurality of doses of medicine from a medicine delivery device to a user over a plurality of days;

measuring, via a sensor disposed within the medicine delivery device, each of the plurality of doses of the medicine delivered to the user, wherein the medicine delivery device administers the dose of the medicine to the user to thereby cause the sensor to measure the dose of the medicine administered to the user by the medicine delivery device;

receiving, at a computing device in communication with the medicine delivery device, a signal wirelessly transmitted from the medicine delivery device to the computing device, the signal including the plurality of doses of medicine delivered from the medicine delivery device to the user over the plurality of days as measured by the sensor;

categorizing each dose of the plurality of doses into one of a plurality of time blocks throughout a 24-hour timeframe;

determining, based on a time block of the plurality of time blocks having the least amount of doses of the plurality of doses, a fasting period end time of the user; and

selecting a physiological parameter reading from a plurality of physiological parameter readings as a physiological parameter reading of interest based on a proximity of a time of the physiological parameter reading to the determined fasting period end time of the user, wherein the medicine delivery device is used to administer an adjusted dose of the medicine to the user.

11. The method according to claim 10 , wherein the physiological parameter readings are a plurality of blood glucose readings and the physiological parameter reading of interest is a fasting blood glucose reading.

12. The method according to claim 11 , further comprising:

determining a fasting period start time based on the fasting period end time; and

selecting a blood glucose reading from the plurality of blood glucose readings as a pre-fasting blood glucose reading based on a proximity of a time of the blood glucose reading to the fasting period start time.

13. The method according to claim 12 , further comprising:

determining whether a risk of hypoglycemia is too high; and

where it is determined that the risk of hypoglycemia is too high, calculating a dose amount decrease for adjusting a dose amount delivered by the medicine delivery device.

14. The medicine administration and tracking system according to claim 1 , wherein the instructions are further operable, when executed by the processor, to cause the computing device to:

set a default fasting period of the user based on the computing device receiving the dose information for a number of days of the predetermined period of days that is less than a predetermined threshold number of days.

15. The medicine administration and tracking system according to claim 1 , wherein the instructions are further operable, when executed by the processor, to cause the computing device to:

generate, for each time block of the plurality of time blocks, a vector of bolus frequencies based on the dose information received for that time block across all the days of the predetermined period of days;

calculate a rolling sum value for each vector of bolus frequencies; and

identify at least one daily time value across all the days of the predetermined period of days that has a minimum rolling sum value.

16. The method according to claim 10 , further comprising:

setting a default fasting period of the user based on the computing device receiving the dose information for a number of days of the predetermined period of days that is less than a predetermined threshold number of days.

17. The method according to claim 10 , further comprising:

generating, for each time block of the plurality of time blocks, a vector of bolus frequencies based on the dose information received for that time block across all the days of the predetermined period of days;

calculating a rolling sum value for each vector of bolus frequencies; and

identifying at least one daily time value across all the days of the predetermined period of days that has a minimum rolling sum value.

Assignments (3)
SECURITY INTEREST Recorded Jan 16, 2026
From: MEDTRONIC MINIMED, INC.; COMPANION MEDICAL, INC.
To: CITIBANK, N.A.
Reel/Frame 074394/0237 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 26, 2022
From: COMPANION MEDICAL, INC.
To: MEDTRONIC MINIMED, INC.
Reel/Frame 060029/0566 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 22, 2021
From: MENSINGER, MICHAEL; GAETANO, ANGELA; SMITH, MADISON; IM, HEUNG YONG; PASCUAL, FRANCIS; BENKE, JASPER; THANASEKARAN, SNEHA
To: COMPANION MEDICAL, INC.
Reel/Frame 055676/0670 →
Continuity (2)
Provisional Application 62993592 · Mar 23, 2020
Related Publication 20210295976A1 · Sep 23, 2021
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