IP Library › Granted Patent US 12,194,129
Granted Patent B2
US 12,194,129 · App. 18/530,533 · Granted Jan 14, 2025

Leave-on oral care compositions

Inventors: Ross Strand (Singapore, SG); Yang Su (Beijing, CN); Yunming Shi (Beijing, CN); Thanigaivel Shanmugam (Beijing, CN); Guannan Wang (Beijing, CN); Xiaoxiao Li (Beijing, CN)
Assignee: The Procter & Gamble Company
A61K8/735A61K8/042A61K8/4946A61K8/8147A61Q11/00A61K2800/30A61K2800/87A61K2800/92
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Quick Facts
Patent No.
US 12,194,129
App. No.
18/530,533
Granted
Jan 14, 2025
Kind
B2
Abstract

Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Leave-on oral care compositions can comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer, and an additional polymer.

Claims (26)

1. A leave-on oral care composition comprising:

a) from about 0.1% to about 10%, by weight of the composition, of a hyaluronic acid or a salt thereof, wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 2,000,000 Daltons;

b) from about 0.5% to about 10%, by weight of the composition, of a polyacrylic acid;

c) from about 0.5% to about 10%, by weight of the composition, of an additional polymer, wherein the additional polymer does not include an anionic cellulose; and

d) from about 30% to about 75%, by weight of the composition, of total water content.

2. The leave-on oral care composition of claim 1 , wherein the hyaluronic acid is present in an amount of from about 0.1% to about 5%, by weight of the composition.

3. The leave-on oral care composition of claim 1 , wherein the polyacrylic acid is present in the amount of from about 0.5% to about 5%, by weight of the composition.

4. The leave-on oral care composition of claim 1 , further comprising from about 0.01% to about 5%, by weight of the composition, of allantoin.

5. The leave-on oral care composition of claim 1 , wherein the additional polymer is selected from the group consisting of natural gum, linear sulfated polysaccharide, nonionic cellulose derivative, co-polymers of maleic anhydride with methyl vinyl ether, polyvinyl pyrrolidine, and combinations thereof.

6. The leave-on oral care composition of claim 5 , wherein the additional polymer is present in the amount of from about 0.2% to about 10%, by weight of the composition.

7. The leave-on oral care composition of claim 5 , wherein the additional polymer is selected from the group consisting of xanthan gum, carrageenan, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, polyvinyl pyrrolidine, and combinations thereof.

8. The leave-on oral care composition of claim 1 , further comprising a polyol selected from the group consisting of glycerol, erythritol, xylitol, sorbitol, mannitol, and combinations thereof.

9. The leave-on oral care composition of claim 8 , wherein the polyol is present in the amount of from about 1% to about 30%, by weight of the composition.

10. The leave-on oral care composition of claim 1 , further comprising a vitamin selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.

11. The leave-on oral care composition of claim 1 , wherein the total water content is from about 40% to about 75%, by weight of the composition.

12. The leave-on oral care composition of claim 1 , wherein the oral care composition is in a gel form.

13. The leave-on oral care composition of claim 1 , wherein the oral care composition is substantially free of abrasives.

14. A method of improving gum health of a subject, the method comprising the steps of applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue a duration of time of from about 1 minute to about 1000 minutes.

15. The method of claim 14 , wherein the applying step is conducted as a last step of an oral hygiene regimen.

16. The method of claim 14 , wherein the leave-on oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

17. A method of improving gum health of a subject, the method comprising the steps of:

(a) brushing teeth of the subject with an antibacterial toothpaste; and

(b) subsequently, applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue for a duration of time of from about 1 minute to about 1000 minutes.

18. The method of claim 17 , wherein the oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

19. A kit comprising a toothpaste and the leave-on oral care composition of claim 1 .

20. A kit comprising the leave-on oral care composition of claim 1 and a delivery carrier, wherein the delivery carrier comprises strip, film of material, dental tray, aligner, sponge material, applicator, or mixtures thereof.

Priority Claims (2)
WO PCT/CN2019/091294 · Jun 14, 2019 · international
WO PCT/CN2020/095575 · Jun 11, 2020 · international
Continuity (2)
Continuation 16899882 · Jun 12, 2020
Related Publication 20240099957A1 · Mar 28, 2024
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