Real-time guidance of radiofrequency ablation catheter contact orientation with cardiac tissue using optical coherence tomography
View Patent ↗An exemplary system, method and computer-accessible medium for determining particular for a portion(s) of an organ of a patient(s) can be provided, which can include, for example, receiving an in vivo optical coherence tomography (OCT) imaging information for the portion(s), and determining (i) a lesion formation on or in the portion(s), (ii) a contact of a catheter on or with the portion(s), or (iii) an angle of the catheter with respect to the portion(s), by applying a convolutional neural network(s) to the in vivo OCT imaging information.
1. A non-transitory computer-accessible medium having stored thereon computer-executable instructions for determining particular information for at least one portion of an organ of at least one patient, wherein, when a computer arrangement executes the instructions, the computer arrangement is configured to perform procedures comprising:
receiving an in vivo optical coherence tomography (OCT) imaging information for the at least one portion;
determining a contact of a catheter on or with the at least one portion; and
after the determination of the contact of the catheter, determining at least one of (i) a lesion formation on or in the at least one portion, or (ii) an angle of the catheter with respect to the at least one portion, by applying at least one convolutional neural network (CNN) to the in vivo OCT imaging information.
2. The computer-accessible medium of claim 1 , wherein the computer arrangement is configured to determine the angle of the catheter with respect to the at least one portion prior to determining the lesion formation on or in the at least one portion.
3. The computer-accessible medium of claim 2 , wherein the computer arrangement is further configured to cause an ablation of the at least one portion after determining the angle of the catheter with respect to the at least one portion and prior to determining the lesion formation on or in the at least one portion.
4. The computer-accessible medium of claim 1 , wherein the computer arrangement is further configured to cause an ablation of the at least one portion.
5. The computer-accessible medium of claim 4 , wherein the computer arrangement is configured to cause the ablation using a radiofrequency ablation arrangement.
6. The computer-accessible medium of claim 1 , wherein the determining the contact of the catheter on or with the at least one portion includes determining a contact or no contact.
7. The computer-accessible medium of claim 1 , wherein the angle includes one of (i) 0 degrees, (ii) 30 degrees, or (iii) 60 degrees.
8. The computer-accessible medium of claim 1 , wherein the computer arrangement is further configured to classify the at least one portion by applying the at least one CNN to the in vivo OCT imaging information.
9. The computer-accessible medium of claim 8 , wherein the computer arrangement is configured to classify the at least one portion as (i) treated or (ii) untreated.
10. The computer-accessible medium of claim 1 , wherein the at least one CNN includes at least 3 CNNs, and wherein the first, second and third CNNs are different from one another.
11. A non-transitory computer-accessible medium having stored thereon computer-executable instructions for determining particular information for at least one portion of an organ of at least one patient, wherein, when a computer arrangement executes the instructions, the computer arrangement is configured to perform procedures comprising:
receiving an in vivo optical coherence tomography (OCT) imaging information for the at least one portion; and
applying at least one convolutional neural network (CNN) to the in vivo OCT imaging information determine the at least one of (i) a lesion formation on or in the at least one portion by applying a first CNN of the at least one CNN, (ii) a contact of the catheter on or with the at least one portion by applying a second CNN of the at least one CNN, or (iii) an angle of the catheter with respect to the at least one portion by applying a third CNN of the at least one CNN.
12. The computer-accessible medium of claim 11 , wherein the contact of the catheter is determined by applying the second CNN that includes at least six layers.
13. The computer-accessible medium of claim 12 , wherein three of the six layers are consecutive rectified linear units (ReLU)-activated convolutional+Max Pooling layers.
14. The computer-accessible medium of claim 13 , wherein the consecutive ReLU-activated convolutional+Max Pooling layers have a kernel size of 3×1.
15. The computer-accessible medium of claim 14 , wherein one of the six layers is a ReLU-activated fully connected layer.
16. The computer-accessible medium of claim 15 , wherein eight of the at least thirteen layers are consecutive rectified linear units (ReLU)-activated convolutional+Max Pooling layers+Average Pooling layers.
17. The computer-accessible medium of claim 16 , wherein two of the at least thirteen layers are ReLU-activated fully connected layers.
18. The computer-accessible medium of claim 11 , wherein the third CNN includes at least thirteen layers.
19. A method for determining particular information for at least one portion of an organ of at least one patient, comprising:
receiving an in vivo optical coherence tomography (OCT) imaging information for the at least one portion;
determining a contact of a catheter on or with the at least one portion; and
after the determination of the contact of the catheter, with a computer hardware arrangement, determining at least one of (i) a lesion formation on or in the at least one portion, or (ii) an angle of the catheter with respect to the at least one portion, by applying at least one convolutional neural network to the in vivo OCT imaging information.
20. A system for determining particular information for at least one portion of an organ of at least one patient, comprising:
a computer hardware arrangement configured to:
receive an in vivo optical coherence tomography (OCT) imaging information for the at least one portion;
determining a contact of a catheter on or with the at least one portion; and
after the determination of the contact of the catheter, determine at least one of (i) a lesion formation on or in the at least one portion, or (ii) an angle of the catheter with respect to the at least one portion, by applying at least one convolutional neural network to the in vivo OCT imaging information.
21. A method for determining particular information for at least one portion of an organ of at least one patient, comprising:
receiving an in vivo optical coherence tomography (OCT) imaging information for the at least one portion; and
applying at least one convolutional neural network (CNN) to the in vivo OCT imaging information determine the at least one of (i) a lesion formation on or in the at least one portion by applying a first CNN of the at least one CNN, (ii) a contact of the catheter on or with the at least one portion by applying a second CNN of the at least one CNN, or (iii) an angle of the catheter with respect to the at least one portion by applying a third CNN of the at least one CNN.
22. A system for determining particular information for at least one portion of an organ of at least one patient, comprising:
a computer hardware arrangement configured to:
receive an in vivo optical coherence tomography (OCT) imaging information for the at least one portion; and
apply at least one convolutional neural network (CNN) to the in vivo OCT imaging information determine the at least one of (i) a lesion formation on or in the at least one portion by applying a first CNN of the at least one CNN, (ii) a contact of the catheter on or with the at least one portion by applying a second CNN of the at least one CNN, or (iii) an angle of the catheter with respect to the at least one portion by applying a third CNN of the at least one CNN.