Granted Patent
B2
US 12,202,802 · App. 17/507,028 · Granted Jan 21, 2025
Styryl quinolinium, process for their preparation and use thereof as fluorescent probes for imaging
Inventors:
Bilha Fischer (Shoham, IL); Abed Elhady Saady (Bu'eine Nujeidat, IL); Yaron Shav-Tal (Elkana, IL); Eli Varon (Nehalim, IL)
Assignee:
BAR ILAN UNIVERSITY
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Abstract
The present invention is directed to styryl quinolinium compounds, a process for their synthesis and their use for selective nucleoli staining in cells, preferably in living cells and for imaging rRNA.
Claims (2)
1. The compound (E)-2-(3, 5-Difluoro-4-hydroxystyryl)-1-methylquinolinium iodide (I-e).
2. A method for imaging rRNA, comprising adding the compound of claim 1 to a sample containing rRNA, and imaging the fluorescence.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 28, 2021
From: FISCHER, BILHA; SAADY, ABED ELHADY; SHAV-TAL, YARON; VARON, ELI
To: BAR ILAN UNIVERSITY
Reel/Frame 058487/0540 →
Continuity (2)
Provisional Application
63094360
· Oct 21, 2020
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