IP Library › Granted Patent US 12,213,820
Granted Patent B2
US 12,213,820 · App. 17/790,088 · Granted Feb 4, 2025

High resolution and high sensitivity pet scanner with pet detector modules

Inventors: Andrew Labella (New Rochelle, NY); Amirhossein Goldan (Stony Brook, NY); Wei Zhao (East Setauket, NY); Eric Petersen (Stony Brook, NY)
Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
A61B6/4208A61B6/037A61B6/4488A61B6/461G01T1/202
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Quick Facts
Patent No.
US 12,213,820
App. No.
17/790,088
Granted
Feb 4, 2025
Kind
B2
Abstract

The disclosure is directed to a device that includes a cavity formed by a plurality of rails, the plurality of rails connected to both a first support and a second support, each at predetermined intervals about a circumference of the first support and the second support; and at least one particle detection device operably connected to each rail of the plurality of rails. The disclosure is also directed to a scanner that includes the device, and a processor.

Claims (31)

1. A device, the device comprising:

a first support;

a second support spaced from the first support in an axial direction;

a plurality of rails each respectively connected to an exterior-facing side of the first support and an exterior-facing side of the second support, the plurality of rails extending between the first support and the second support where at least a part of the plurality of rails is orthogonal to the first support and the second support, the plurality of rails, the first support and the second support defining a cavity, the exterior-facing side of the first support and the exterior-facing side of the second support being a side opposite to a side of the first support and a side of the second support facing the cavity, the rails being disposed at predetermined intervals about a circumference of the first support and the second support; and

a plurality of particle detection devices operably connected to each rail of the plurality of rails in a row of particle detection devices, where a respective rail overlaps at least part of the row of particle detection devices in a radial direction, each particle detection device comprising:

a scintillator array comprising a plurality of scintillator crystals;

a plurality of detectors provided on a bottom end of the scintillator array; and

a plurality of prismatoids provided on a top end of the scintillator array, wherein each prismatoid of the plurality of prismatoids is configured to redirect particles between top ends of scintillator crystals of the scintillator array,

wherein bottom ends of a first group of scintillator crystals of the scintillator array are configured to direct particles to a first detector of the plurality of detectors, and

wherein bottom ends of a second group of scintillator crystals of the scintillator array are configured to direct particles to a second detector substantially adjacent to the first detector,

wherein the plurality of prismatoids of each particle detection device is oriented towards the cavity.

2. The device of claim 1 , wherein each row of particle detection devices comprises multiple aligned particle detection devices.

3. The device of claim 1 , wherein the plurality of rails comprises at least four rails.

4. The device of claim 1 , further comprising an internal shield configured to be between the plurality of particle detection devices and the cavity.

5. The device of claim 4 , further comprising an external guard that extends axially.

6. The device of claim 5 , further comprising a first cap and a second cap, wherein the first cap and the second cap each extend circumferentially between a space between the internal shield and the external guard.

7. The device of claim 5 , wherein the rows of particle detection devices are between the internal shield and the external guard in the radial direction.

8. The device of claim 1 , further comprising a plurality of internal guards, wherein each of the plurality of internal guards extend axially between two of the plurality of rails.

9. The device of claim 8 , wherein each of the plurality of internal guards further provides a barrier between rows of particle detection devices in different rails.

10. The device of claim 1 , wherein the cavity is dimensioned to extend about a mammal's head.

11. The device of claim 1 , wherein the cavity is dimensioned to extend about a mammal's torso.

12. The device of claim 1 , wherein the each prismatoid is substantially shaped as at least one of at least one prism, at least one antiprism, at least one frustum, at least one triangle, at least one cupola, at least one parallelepiped, at least one wedge, at least one pyramid, at least one truncated pyramid, and at least one portion of a sphere.

13. The device of claim 1 , wherein the device has a substantially ovular cross section.

14. A positron emission tomography (PET) scanner for acquiring a PET image, the scanner comprising:

the device of claim 1 ; and

at least one processor in operative communication with the plurality of detectors of each of the plurality of particle detection devices, wherein the at least one processor comprises a plurality of algorithms configured to perform three dimensional (3D) gamma ray localization of at least one interaction site within at least one scintillator crystal of the plurality of scintillator crystals.

15. The scanner of claim 14 , wherein the at least one processor is further configured to determine a Compton event localization.

16. The scanner of claim 14 , wherein the at least one processor is configured to perform Depth of Interaction (DOI) localization within the scintillator crystals using an energy-weighted algorithm.

17. The scanner of claim 14 , further comprising a patient support that is configured to move axially within the scanner.

18. The scanner of claim 14 , further comprising a display for displaying the PET image.

19. The scanner of claim 14 , further comprising a coolant system configured to deliver a coolant to each of the plurality of particle detection devices via the rails.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 27, 2024
From: LABELLA, ANDREW; GOLDAN, AMIRHOSSEIN; ZHAO, WEI; PETERSEN, ERIC
To: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Reel/Frame 069688/0009 →
Continuity (2)
Provisional Application 62962347 · Jan 17, 2020
Related Publication 20230052635A1 · Feb 16, 2023
References Cited (72)
US 4531058A · Burnham et al. · 1985 [cited by applicant]
US 6346706B1 · Rogers et al. · 2002 [cited by applicant]
US 7088901B2 · Kim et al. · 2006 [cited by applicant]
US 7750311B2 · Daghighian · 2010 [cited by applicant]
US 8519710B2 · Schulz et al. · 2013 [cited by applicant]
US 9835737B1 · Czarnecki et al. · 2017 [cited by applicant]
US 20040227091A1 · LeBlanc et al. · 2004 [cited by applicant]
US 20060241386A1 · Yanagita · 2006 [cited by examiner]
US 20120061577A1 · Oleinik · 2012 [cited by examiner]
US 20120068076A1 · Daghighian · 2012 [cited by applicant]
US 20120112078A1 · Millett et al. · 2012 [cited by applicant]
US 20130009063A1 · Henseler et al. · 2013 [cited by applicant]
US 20130256536A1 · Kim · 2013 [cited by applicant]
US 20130306876A1 · Uchida · 2013 [cited by applicant]
US 20150005616A1 · Saha · 2015 [cited by applicant]
US 20160187496A1 · Bradford et al. · 2016 [cited by applicant]
US 20180177473A1 · Gregerson et al. · 2018 [cited by applicant]
US 20180344274A1 · Berr et al. · 2018 [cited by applicant]
US 20190000406A1 · Liu et al. · 2019 [cited by applicant]
US 20190142352A1 · Liu et al. · 2019 [cited by applicant]
US 20190331810A1 · Yan et al. · 2019 [cited by applicant]
US 20190353807A1 · Furenlid et al. · 2019 [cited by applicant]
US 20200345322A1 · Bai et al. · 2020 [cited by applicant]
US 20210196211A9 · Tai et al. · 2021 [cited by applicant]
US 20220120923A1 · Goldan et al. · 2022 [cited by applicant]
US 20220211334A1 · Furenlid et al. · 2022 [cited by applicant]
US 20240277305A1 · Muelhens · 2024 [cited by examiner]
CN 1813202A · 2006 [cited by applicant]
CN 102805630A · 2012 [cited by applicant]
CN 105190360A · 2015 [cited by applicant]
CN 105988152A · 2016 [cited by applicant]
CN 206725802U · 2017 [cited by applicant]
CN 111025370A · 2020 [cited by applicant]
CN 107110980B · 2020 [cited by applicant]
CN 111443377A · 2020 [cited by applicant]
CN 112771412A · 2021 [cited by applicant]
CN 113009548A · 2021 [cited by applicant]
CN 113069133A · 2021 [cited by applicant]
CN 113359179A · 2021 [cited by applicant]
CN 113631960A · 2021 [cited by applicant]
DE 102009003792A1 · 2009 [cited by applicant]
EP 1627239B1 · 2006 [cited by applicant]
EP 1875273B1 · 2011 [cited by applicant]
EP 3030154B1 · 2020 [cited by applicant]
EP 3924754A1 · 2021 [cited by applicant]
JP 9325185A · 1997 [cited by applicant]
JP WO2010070737A1 · 2010 [cited by applicant]
JP 2011106981A · 2011 [cited by applicant]
JP 2012173128A · 2012 [cited by applicant]
JP 5080910B2 · 2012 [cited by applicant]
JP 5104951B2 · 2012 [cited by applicant]
JP 2013542415A · 2013 [cited by applicant]
JP 2015501435A · 2015 [cited by applicant]
JP 5707269B2 · 2015 [cited by applicant]
JP 201630082A · 2016 [cited by applicant]
JP 2016183962A · 2016 [cited by applicant]
JP 202060545A · 2020 [cited by applicant]
WO 2007120674A2 · 2007 [cited by applicant]
WO 2012034220A1 · 2012 [cited by applicant]
WO 2020146475A1 · 2020 [cited by applicant]
WO 2020168205A9 · 2020 [cited by applicant]
WO 2021173708A1 · 2021 [cited by applicant]
WO 2022051506A1 · 2022 [cited by applicant]
WO 2022051579A1 · 2022 [cited by applicant]
WO 2020076643A1 · 2022 [cited by applicant]
Labella A. et al., “Prism Mirror Light Guide for Enhanced Gamma Ray Localization in PET”, IEEE Nuclear Science Symposium and Medical Imaging Conference, pp. 1-4 (Oct. 26, 2019). [cited by applicant]
European Extended Supplementary Search Report dated Jan. 23, 2024 received in European Application No. 21 74 1391.3. [cited by applicant]
International Search Report dated Apr. 22, 2021 issued in PCT/US2021/013638. [cited by applicant]
Written Opinion dated Apr. 22, 2021 issued in PCT/US2021/013638. [cited by applicant]
Marcinkowski R. et al., “Optimized Light Sharing for High-Resolution TOF PET Detector Based on Digital Silicon Photomultipliers”, Physics in Medicine & Biology 59:7125-7139 (2014). [cited by applicant]
Song T Y et al., “A Sub-Millimeter Resolution PET Detector Module Using a Multi-Pixel Photon Counter Array”, Physics in Medicine & Biology 55:2573-2587 (2010). [cited by applicant]
Notice of Reasons for Rejection dated Sep. 9, 2024 received in Japanese Patent Application No. 2022-538445. [cited by applicant]