IP Library › Granted Patent US 12,214,155
Granted Patent B2
US 12,214,155 · App. 18/048,931 · Granted Feb 4, 2025

Fluid injector system volume compensation system and method

Inventors: Michael Mcdermott (Berlin, DE); Michael Spohn (Fenelton, PA); William Barone (Pittsburgh, PA); Chelsea Marsh (Pittsburgh, PA)
Assignee: BAYER HEALTHCARE LLC
A61M5/007A61M5/1408A61M5/14228A61M5/14546A61M5/14586A61M5/148A61M5/16877A61M5/16881A61M2005/14208A61M2005/14553A61M2205/3331A61M2205/3389
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Quick Facts
Patent No.
US 12,214,155
App. No.
18/048,931
Granted
Feb 4, 2025
Kind
B2
Abstract

A system and method for correcting a volume of fluid delivered by a fluid injector during an injection procedure is described. The method included determining and compensating for a volume factor associated with compliance of the fluid injector system and correcting for the volume by one of over-driving the distance that the drive member travels in a fluid reservoir, under-driving the distance that the drive member travels in the fluid reservoir, or lengthening or shortening a fluid delivery time.

Claims (52)

1. A method for correcting a volume of fluid delivered by a fluid injector system during an injection procedure, the method comprising:

determining a fluid volume of a first fluid in at least one fluid reservoir of the fluid injector system;

determining a pressure at which a first programmed volume of the first fluid is to be injected;

calculating a first system volume compliance of the at least one fluid reservoir, one or more fluid injector mechanical components associated with the fluid injector system, and one or more tubing system components based on: the volume of the first fluid, the pressure of the first fluid, and one or more correction factors based on capacitance characteristics of the at least one fluid reservoir and one or more tubing system components, fluid properties of the first fluid, and a component slack of the one or more fluid injector mechanical components associated with the fluid injector system;

calculating a first volume compliance factor of the first fluid in the at least one fluid reservoir based on the first programmed volume of the first fluid and the calculated first system volume compliance; and

compensating for the first volume compliance factor to deliver the first programmed volume by one of: over-driving a distance that a first drive member travels in the at least one fluid reservoir, under-driving the distance that the first drive member travels in the at least one fluid reservoir, increasing a delivery time of the first fluid in the at least one fluid reservoir, and decreasing the delivery time of the first fluid in the at least one fluid reservoir.

2. The method of claim 1 , wherein the at least one fluid reservoir comprises at least one first fluid reservoir containing the first fluid and at least one second fluid reservoir containing a second fluid, wherein the method further comprises: determining a fluid volume of the second fluid in the at least one second fluid reservoir of the fluid injector system; determining a second pressure at which a second programmed volume of the second fluid is to be injected; calculating a second system volume compliance of the at least one second fluid reservoir, the one or more fluid injector mechanical components associated with the fluid injector system, and the one or more tubing system components based on: the volume of the second fluid, the pressure of the second fluid, and one or more correction factors based on capacitance characteristics of the at least one second reservoir and one or more tubing system components, fluid properties of the second fluid, and the component slack of the one or more fluid injector mechanical components associated with the fluid injector system; calculating a second volume compliance factor of the second fluid in the at least one second fluid reservoir based on the second programmed volume of the second fluid and the calculated second system volume compliance; and compensating for the second volume compliance factor to deliver the second programmed volume by one of: over-driving a distance that a second drive member travels in the at least one second fluid reservoir, under-driving the distance that the second drive member travels in the at least one second fluid reservoir, increasing a delivery time of the second fluid in the at least one second fluid reservoir, and decreasing the delivery time of the second fluid in the at least one second fluid reservoir.

3. The method of claim 1 , further comprising the step of determining whether the at least one fluid reservoir contains at least a volume of the first fluid corresponding to the programmed volume plus an amount of the first fluid equal to the calculated system volume compliance of the at least one fluid reservoir.

4. The method of claim 2 , wherein the at least one first fluid reservoir and the at least one second fluid reservoir are independently selected from a group consisting of a syringe, a rolling diaphragm syringe, a peristaltic pump, and a compressible bag.

5. The method of claim 2 , wherein at least one of the at least one first fluid reservoir and the at least one second fluid reservoir is a syringe.

6. The method of claim 5 , wherein the syringe comprises a plunger operatively connected to a piston selected from a linear actuated piston and a motor driven piston.

7. The method of claim 2 , wherein at least one of the at least one first fluid reservoir and the at least one second fluid reservoir is a rolling diaphragm syringe.

8. The method of claim 7 , wherein a proximal end of the rolling diaphragm syringe is operatively connected to a piston selected from a linear actuated piston and a motor driven piston.

9. The method of claim 1 , wherein the first system volume compliance is calculated according to Equation (1):

C 1 =A 1 ·V 1 +B 1 ·P 1 +O 1   (1)

where C 1 is the first system volume compliance of the at least one fluid reservoir, A 1 is a position scalar of the at least one fluid reservoir, V 1 is available volume of the at least one fluid reservoir, B 1 is a pressure constant of the at least one fluid reservoir, P 1 is a pressure of fluid within the at least one fluid reservoir, and O 1 is the compensation factor of the at least one fluid reservoir.

10. The method of claim 2 , wherein the second system volume compliance is calculated according to Equation (2):

C 2 =A 2 ·V 2 +B 2 ·P 2 +O 2   (2)

where C 2 is the second system volume compliance of the at least one second fluid reservoir, A 2 is a position scalar of the at least one second fluid reservoir, V 2 is available volume of the at least one second fluid reservoir, B 2 is a pressure constant of the at least one second fluid reservoir, P 2 is a pressure of fluid within the at least one second fluid reservoir, and O 2 is the compensation factor of the at least one second fluid reservoir.

11. The method of claim 8 , wherein the first volume compliance factor is calculated according to Equation (3):

VC 1 =PV 1 +C 1   (3)

where VC 1 is the first volume compliance factor of the first fluid in the at least one fluid reservoir, PV 1 is the programmed volume of the first fluid, and C 1 is the first system volume compliance of the at least one fluid reservoir; and

wherein the second volume compliance factor is calculated according to Equation (4):

VC 2 =PV 2 +C 2   (4)

where VC 2 is the second volume compliance factor of the second fluid in the at least one second fluid reservoir, PV 2 is the programmed volume of the second fluid, and C 2 is the second system volume compliance of the at least one second fluid reservoir.

12. The method of claim 1 , wherein compensating for the first volume compliance factor the at least one fluid reservoir comprises:

over-driving the distance that the first drive member travels in the at least one fluid reservoir; and

injecting an additional volume of the first fluid equal to the calculated first volume compliance factor.

13. The method of claim 12 , further comprising closing a valve to fluidly isolate the at least one fluid reservoir from the patient after injecting the additional volume of the first fluid.

14. The method of claim 1 , wherein compensating for the second volume compliance factor the at least one second fluid reservoir comprises:

over-driving the distance that the second drive member travels in the at least one second fluid reservoir; and

injecting an additional volume of the second fluid equal to the calculated second volume compliance factor.

15. The method of claim 14 , further comprising closing a valve to fluidly isolate the at least one second fluid reservoir from the patient after injecting the additional volume of the second fluid.

16. The method of claim 1 , further comprising reporting to a user a value corresponding to corrected volume of the first fluid being delivered to a patient from the at least one fluid reservoir, wherein the corrected volume accounts for the first programmed volume and the first system volume compliance.

17. A fluid delivery system comprising:

a fluid injector;

at least one first fluid reservoir configured to contain a first fluid;

at least one first drive member configured to drive the first fluid from the at least one first fluid reservoir; and

a controller in operable communication with the at least one first drive member, wherein the controller comprises computer readable memory containing instructions that, when executed by the controller, cause the controller to:

determine a fluid volume of the first fluid in at least one first fluid reservoir;

determine a pressure at which a first programmed volume of the first fluid is to be injected;

calculate a first system volume compliance of the at least one first fluid reservoir, one or more fluid injector mechanical components associated with the fluid injector, and one or more tubing system components based on: the volume of the first fluid, the pressure of the first fluid, and one or more correction factors based on capacitance characteristics of the at least one first fluid reservoir and one or more tubing system components, fluid properties of the first fluid, and a component slack of the one or more fluid injector mechanical components associated with the fluid injector;

calculate a first volume compliance factor of the first fluid in the at least one first fluid reservoir based on the first programmed volume of the first fluid and the calculated first system volume compliance; and

compensate for the first volume compliance factor to deliver the first programmed volume by one of: over-driving a distance that the at least one first drive member travels in the at least one fluid reservoir, under-driving the distance that the at least one first drive member travels in the at least one fluid reservoir, increasing a delivery time of the first fluid in the at least one fluid reservoir, and decreasing the delivery time of the first fluid in the at least one fluid reservoir.

18. The fluid delivery system of claim 17 , wherein the controller is configured to calculate the first system volume compliance volume according to Equation (1):

C 1 =A 1 ·V 1 +B 1 ·P 1 +O 1   (1)

where C 1 is the first system volume compliance of the at least one first fluid reservoir, A 1 is a position scalar of the at least one first fluid reservoir, V 1 is available volume of the at least one fluid reservoir, B 1 is a pressure constant of the at least one first fluid reservoir, P 1 is a pressure of fluid within the at least one first fluid reservoir, and O 1 is the compensation factor of the at least one first fluid reservoir.

19. The fluid delivery system of claim 17 , wherein the computer readable memory containing further instructions that, when executed by the controller, causes the controller to compensate for the first volume compliance factor by:

over-driving the distance that the at least one first drive member travels in the at least one first fluid reservoir; and

injecting an additional volume of the first fluid equal to the calculated first volume compliance factor.

20. The fluid delivery system of claim 17 , wherein the computer readable memory containing further instructions that, when executed by the controller, causes the controller to compensate for the first volume compliance factor by:

increasing the delivery time of the first fluid in the at least one first fluid reservoir by an amount sufficient to deliver an additional volume of the first fluid equal to the calculated first volume compliance factor.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2022
From: MCDERMOTT, MICHAEL; SPOHN, MICHAEL; BARONE, WILLIAM; MARSH, CHELSEA
To: BAYER HEALTHCARE LLC
Reel/Frame 061512/0717 →
Continuity (3)
Continuation 16621164
Provisional Application 62552430 · Aug 31, 2017
Related Publication 20230069601A1 · Mar 2, 2023
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