IP Library › Granted Patent US 12,220,509
Granted Patent B2
US 12,220,509 · App. 16/480,550 · Granted Feb 11, 2025

Smart peritoneal dialysis device

Inventors: Hezkiah Tsoory (Maor, IL); Shahar Harari (Tel-Aviv, IL)
Assignee: LIBERDI LTD.
A61M1/28A61M1/282A61M5/14228A61M2205/3553A61M2205/52A61M2230/00
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Quick Facts
Patent No.
US 12,220,509
App. No.
16/480,550
Granted
Feb 11, 2025
Kind
B2
Abstract

A device for monitoring and/or modifying a peritoneal dialysis treatment, including: a memory which stores at least one treatment protocol; a control circuitry connected to the memory, wherein said control circuitry generates a report and/or modifies the treatment if an outcome of the treatment is not a desired outcome of the treatment protocol.

Claims (32)

1. A device for monitoring and/or modifying a peritoneal dialysis treatment of a patient, the device comprising:

a memory which stores at least one treatment protocol;

a control circuitry connected to the memory, wherein the control circuitry is configured to perform the following:

receiving instructions to execute a treatment protocol of the at least one treatment protocol;

measuring properties of output light passing through fresh peritoneal dialysate fluid;

measuring properties of output light passing through drained peritoneal dialysate fluid;

comparing the properties of light that passed through fresh peritoneal dialysate fluid with properties of light that passed through drained peritoneal dialysate fluid;

determining, based on the comparing, a patient physiological condition;

generating a patient compliance report, wherein the patient compliance report indicates a variation of at least one treatment parameter from the treatment protocol, and the patient physiological condition; and

modifying, based on the patient compliance report, the treatment protocol by modifying at least one treatment parameter of the treatment protocol to compensate for the variation from the treatment protocol, wherein the modifying includes modifying a content of the fresh peritoneal dialysate fluid.

2. The device of claim 1 , further comprising a tubing shaped and sized to allow a flow of a fluid into a catheter, and wherein said control circuitry modifies said peritoneal dialysis treatment based on said flow of said fluid and/or based on a content of said fluid within said tubing.

3. The device of claim 2 , comprising:

a pump rotor in association with said tubing, wherein said pump rotor is configured to move said fluid, and wherein said control circuitry modifies said peritoneal dialysis treatment by modifying a rotation of said pump rotor.

4. The device of claim 1 , wherein said comparing further comprises comparing between measured drained peritoneal dialysate values and fresh peritoneal dialysate values to allow for self-calibration of the device.

5. The device of claim 4 , wherein said self-calibration is employed to minimize variations due to different batches of the fresh peritoneal dialysate fluid.

6. The device of claim 1 , wherein said comparing generates a score or differentiating parameter value that is indicative a number of white blood cells found in at least a partial volume of the drained peritoneal dialysate fluid.

7. The device of claim 1 , wherein the comparing generates a score for each wavelength or for each range of wavelengths separately.

8. The device of claim 7 , wherein said control circuitry is configured to detect, based on the comparing, peritonitis.

9. The device of claim 1 , wherein at least one light sensor is connected to said control circuitry for measuring absorption and/or scattering of light passing through said drained and/or fresh peritoneal dialysate fluid in one or more wavelengths in a range of at least one of: 500-650 nm and 150-350 nm.

10. The device of claim 1 , wherein the control circuitry is configured to select a peritonitis treatment.

11. The device of claim 1 , wherein said control circuitry modifies, based on the comparing, said peritoneal dialysis treatment or selects a different treatment protocol of the at least one treatment protocol stored in said memory.

12. The device of claim 1 , wherein the properties comprise at least one of the following: light absorption, light scattering, fluid turbidity, or any combination thereof.

13. The device of claim 1 , wherein said comparing generates a score that is based on at least one clinical parameter of the patient.

14. The device of claim 1 , wherein the measured properties of output light passing through the drained peritoneal dialysate fluid indicate the at least one treatment parameter of the executed treatment protocol.

15. A method for monitoring and/or modifying a peritoneal dialysis treatment of a patient, the method comprising:

receiving instructions to execute a treatment protocol;

measuring properties of output light passing through fresh peritoneal dialysate fluid;

measuring properties of output light passing through drained peritoneal dialysate fluid;

comparing the properties of light that passed through fresh peritoneal dialysate fluid with properties of light that passed through drained peritoneal dialysate fluid;

determining, based on the comparing, a patient physiological condition;

generating a patient compliance report, wherein the patient compliance report indicates a variation of at least one treatment parameter from the treatment protocol, and the patient physiological condition; and

modifying, based on the patient compliance report, the treatment protocol by modifying at least one treatment parameter of the treatment protocol to compensate for the variation from the treatment protocol, wherein the modifying includes modifying a content of the fresh peritoneal dialysate fluid.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2019
From: TSOORY, HEZKIAH; HARARI, SHAHAR
To: LIBERDI LTD.
Reel/Frame 049850/0234 →
Priority Claims (1)
WO PCT/IL2017/050117 · Feb 1, 2017 · international
Continuity (2)
Provisional Application 62488944 · Apr 24, 2017
Related Publication 20190381231A1 · Dec 19, 2019
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