IP Library › Granted Patent US 12,222,360
Granted Patent B2
US 12,222,360 · App. 17/603,725 · Granted Feb 11, 2025

Automatic analyzer with nozzle connected to flow cell detector and a nozzle cleaning tank

Inventors: Yoshihiro Kabe (Tokyo, JP); Takenori Okusa (Tokyo, JP)
Assignee: HITACHI HIGH-TECH CORPORATION
G01N35/1004G01N35/00712G01N35/025G01N35/08G01N2035/0437
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Quick Facts
Patent No.
US 12,222,360
App. No.
17/603,725
Granted
Feb 11, 2025
Kind
B2
Abstract

An automatic analyzer includes a flow cell detector, a nozzle that is connected to the flow cell detector by a flow path and aspirates or discharges liquid, a reservoir that is provided with a table and a table driving mechanism that rotates or moves the table up and down, and a cleaning tank that is disposed on the table. A position of the nozzle is fixed, and a cleaning water discharge port discharges cleaning water used for cleaning the nozzle at an angle φ with respect to a plane perpendicular to a central axis of the nozzle. An upper part of a side wall of the cleaning tank is continuous with an upper discharge unit at a side facing a discharge outlet provided in the reservoir and a spatula-shaped part projects outward of the cleaning tank at a side facing the upper discharge unit.

Claims (36)

1. An automatic analyzer, comprising:

a flow cell detector;

a nozzle that is connected to the flow cell detector by a flow path and aspirates or discharges liquid;

a reservoir that is provided with a table and a table driving mechanism that rotates the table or moves the table up and down; and

a cleaning tank that is disposed on the table, wherein

a position of the nozzle is fixed, and a cleaning water discharge port that discharges cleaning water used for cleaning the nozzle is fixed such that the cleaning water can be discharged at an angle φ with respect to a plane perpendicular to a central axis of the nozzle, and

an upper part of a side wall of the cleaning tank is continuous with an upper discharge unit at a side facing a discharge outlet provided in the reservoir and a spatula-shaped part that projects outward the cleaning tank at a side facing the upper discharge unit.

2. The automatic analyzer according to claim 1 , wherein

the spatula-shaped part includes an inclined part at an angle θ with respect to the plane perpendicular to the central axis of the nozzle, and

the angle φ>the angle θ.

3. The automatic analyzer according to claim 2 , wherein

the spatula-shaped part includes a U-shaped or V-shaped groove in which the inclined part serves as a bottom of the groove.

4. The automatic analyzer according to claim 2 , wherein

the reservoir includes a reaction vessel holding unit, and

in a case where a range of contacting with reaction liquid is set as a range at a height h 1 from a lower end of the nozzle when the nozzle aspirates the reaction liquid from a reaction vessel that is placed in the reaction vessel holding unit, and a height h 3 is set as a height from the lower end of the nozzle to an intersection point between the nozzle and an extension line of the inclined part of the spatula-shaped part when the reservoir is in a nozzle cleaning position where the nozzle is cleaned by being inserted into the cleaning tank, the height h 3 >the height h 1 .

5. The automatic analyzer according to claim 1 , wherein

a lower part of the side wall of the cleaning tank is provided with a lower discharge unit at the side facing the discharge outlet provided in the reservoir, and a bottom surface of the cleaning tank that is continuous with the lower discharge unit is inclined to the plane perpendicular to the central axis of the nozzle.

6. The automatic analyzer according to claim 5 , wherein

a volume of the cleaning water discharged from the cleaning water discharge port per unit time is a volume of cleaning water stored in the cleaning tank that overflows from the upper discharge unit.

7. The automatic analyzer according to claim 1 , wherein

the spatula-shaped part of the cleaning tank is positioned vertically below the cleaning water discharge port when the reservoir is in a nozzle cleaning position where the nozzle is cleaned by being inserted into the cleaning tank.

8. The automatic analyzer according to claim 7 , wherein

the reservoir includes a reaction vessel holding unit, and

in a case where a range of contacting with reaction liquid is set as a range at a height h 1 from a lower end of the nozzle when the nozzle aspirates the reaction liquid from a reaction vessel that is placed in the reaction vessel holding unit, and an overflow surface of the cleaning tank is at a height h 4 from the lower end of the nozzle when the reservoir is in the nozzle cleaning position, the height h 4 >the height h 1 .

9. The automatic analyzer according to claim 1 , wherein

the reservoir includes a reaction vessel holding unit, and

in a case where a range of contacting with reaction liquid is set as a range at a height h 1 from a lower end of the nozzle when the nozzle aspirates the reaction liquid from a reaction vessel that is placed in the reaction vessel holding unit, and a height h 2 is set as a height from the lower end of the nozzle to an intersection point between the nozzle and an imaginary line that extends from the cleaning water discharge port at the angle φ with respect to the plane perpendicular to the central axis of the nozzle, the height h 2 >the height h 1 .

10. The automatic analyzer according to claim 1 , further comprising:

a liquid container disposed on the table, wherein

a supply port that supplies liquid to the liquid container is fixed, and the reservoir moves the liquid container to match the supply port.

11. The automatic analyzer according to claim 10 , wherein

an upper part of a side wall of the liquid container is continuous with a discharge unit at a side facing the discharge outlet provided in the reservoir.

12. The automatic analyzer according to claim 11 , wherein

discharged liquid that overflows from the upper discharge unit of the cleaning tank or the discharge unit of the liquid container is discharged from a flow path that is continuous with the discharge outlet, and the flow path is provided along a central axis of the table driving mechanism.

13. The automatic analyzer according to claim 12 , wherein

the discharge outlet of the reservoir includes a cylindrical member that faces the upper discharge unit of the cleaning tank and the discharge unit of the liquid container.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 14, 2021
From: KABE, YOSHIHIRO; OKUSA, TAKENORI
To: HITACHI HIGH-TECH CORPORATION
Reel/Frame 057794/0388 →
Priority Claims (1)
JP 2019-091875 · May 15, 2019 · national
Continuity (1)
Related Publication 20220196695A1 · Jun 23, 2022
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