IP Library Granted Patent US 12,232,956
Granted Patent B2
US 12,232,956 · App. 18/195,288 · Granted Feb 25, 2025

Prosthetic heart valve leaflet assemblies and methods

Inventors: Tamir S. Levi (Zikhron Yaakov, IL); Shahram Zamani (Newport Coast, CA); Michael Bukin (Pardes Hanna, IL); Ziv Yohanan (Kfar Hahoresh, IL); Noam Nir (Pardes-Hanna, IL); Tyler Dale O'Dell (Irvine, CA); Elena Sherman (Pardes Hana, IL)
Assignee: EDWARDS LIFESCIENCES CORPORATION
A61F2/2415A61F2/2418A61F2220/0075
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Quick Facts
Patent No.
US 12,232,956
App. No.
18/195,288
Granted
Feb 25, 2025
Kind
B2
Abstract

A method of assembling a valvular structure can include folding an upper tab of a first leaflet onto a lower tab of the first leaflet, disposing a first end of a reinforcing member on the upper tab, disposing a commissure member adjacent the lower tab, and coupling the first end of the reinforcing member, the tabs of the first leaflet, and the commissure member to one another. The method can further include folding an upper tab of a second leaflet onto a lower tab of the second leaflet, disposing the second leaflet adjacent the first leaflet such that the commissure member is positioned between the lower tabs, disposing a second end of the reinforcing member on the upper tab of the second leaflet, and coupling the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another to form a commissure.

Claims (20)

1. A method of assembling a prosthetic heart valve including a valvular structure, comprising:

disposing a first end portion of a reinforcing member an upper tab of a first leaflet, the upper tab disposed over a respective lower tab;

disposing a commissure member adjacent the lower tab of the first leaflet, the commissure member folded to form first and second layers;

coupling the first end portion of the reinforcing member, the upper and lower tabs of the first leaflet, and the commissure member to one another using one or more fastening sutures;

disposing a second leaflet adjacent the first leaflet such that the first and second layers of the commissure member are positioned between a lower tab of the second leaflet and the lower tab of the first leaflet;

disposing a second end portion of the reinforcing member on an upper tab of the second leaflet;

coupling the second end portion of the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another using the one or more fastening sutures to form a commissure;

cutting first and second lateral portions of the commissure member such that lateral edges of the commissure member do not extend past lateral edges of the upper and lower tabs of the first and second leaflets;

sewing one or more securing sutures through the commissure such that they extend around lateral edges of the upper and lower tabs of the first and second leaflets to form a plurality of loops;

sliding the plurality of loops axially over a commissure support portion of a frame of the prosthetic valve such that the leaflets are disposed within the frame; and

tightening the plurality of loops to secure the leaflets to the frame.

2. The method of claim 1 , wherein the first and second layers of the commissure member each comprise an inner layer and an outer layer.

3. The method of claim 1 , wherein the commissure support portion is an expansion and locking mechanism.

4. The method of claim 1 , wherein sewing one or more securing sutures through the commissure comprises sewing the securing sutures through the reinforcing member.

5. The method of claim 4 , wherein the securing sutures extend through the first end portion and second end portion of the reinforcing member.

6. The method of claim 1 , wherein sewing one or more securing sutures through the commissure comprises sewing the securing sutures through the lateral edges of the upper and lower tabs of the first and second leaflets.

7. The method of claim 1 , wherein the reinforcement member comprises at least one of multi-filament suture, braided cloth, metallic braid, and metal strip.

8. The method of claim 1 , wherein the reinforcing member comprises an Ethibond suture.

9. The method of claim 1 , wherein the reinforcing member is radially inset from the lateral edges of the upper and lower tabs of the first and second leaflets.

10. The method of claim 1 , wherein the upper and lower tabs of each leaflet are first integral upper and lower tabs, and wherein each leaflet further comprises second integral upper and lower tabs arranged at an opposing end of a cusp edge portion of the leaflet.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2023
From: LEVI, TAMIR S.; ZAMANI, SHAHRAM; BUKIN, MICHAEL; YOHANAN, ZIV; NIR, NOAM; O'DELL, TYLER DALE; SHERMAN, ELENA
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 064506/0652 →
Continuity (3)
Continuation PCTUS2021058918 · Nov 11, 2021
Provisional Application 63113034 · Nov 12, 2020
Related Publication 20230270541A1 · Aug 31, 2023
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