IP Library Granted Patent US 12,233,145
Granted Patent B2
US 12,233,145 · App. 17/297,351 · Granted Feb 25, 2025

Ultra-violet absorbing compounds

Inventors: Teresa Patricia Pedrosa Martins (Matosinhos, PT); Mariana Alves Reis (Matosinhos, PT); Pedro Nuno Da Costa Leao (Matosinhos, PT); Vitor Manuel Oliveira Vasconcelos (Matosinhos, PT); Meryem Hassouani (El Jadida, MA); Brahim Sabour (El Jadida, MA)
Assignees: CIIMAR—CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL; UNIVERSIDADE DO PORTO; FACULTY OF SCIENCES, CHOUAIB DOUKKALI UNIVERSITY
A61K8/492A61Q17/005A61Q17/04G02B1/041G02B5/003G02C7/10
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Quick Facts
Patent No.
US 12,233,145
App. No.
17/297,351
Granted
Feb 25, 2025
Kind
B2
Abstract

Novel compounds able to absorb UV radiation and comprise antimicrobial properties as well. The compounds are novel and undisclosed scytonemin analogs, able to absorb up to 90% of UV-A radiation and can cover a broader UV to blue light absorption range from 293 nm to 500 nm. When mixtures of more than one compound are used, their synergetic absorption properties can cover an even broader spectrum within 293 nm to 500 nm. The compounds present faint coloration, and some are even colorless, therefor the present compounds can be easily incorporated in formulations to be used in cosmetic products, sunscreens or lenses for sunglasses.

Claims (14)

1. An ultra-violet (UV) radiation absorbing compound selected from 3′-hydroxyscytonemin and 3,3′-dihydroxyscytonemin of formulas:

and stereoisomers thereof, wherein the compound has antibacterial activity.

2. The ultra-violet (UV) radiation absorbing compound according to claim 1 , wherein the compound absorbs light from 293 nm to 500 nm.

3. The ultra-violet (UV) radiation absorbing compound according to claim 1 , wherein the compound absorbs up to 90% of UV-A radiation.

4. The ultra-violet (UV) radiation absorbing compound according to claim 1 , wherein the compound has antioxidant activity.

5. A cosmetic product comprising the ultra-violet (UV) radiation absorbing compounds of claim 1 .

6. A sunscreen product comprising the ultra-violet (UV) radiation absorbing compounds of claim 1 .

7. A pair of sunglasses comprising the ultra-violet (UV) radiation absorbing compounds of claim 1 .

8. A formulation comprising the compounds of claim 1 .

9. The formulation according to claim 8 , wherein the formulation comprises one compound.

10. The formulation according to claim 8 , wherein the formulation comprises more than one compound.

11. A cosmetic product comprising the formulation according to claim 8 .

12. A sunscreen product comprising the formulation according to claim 8 .

13. A lens for sunglasses comprising the formulation according to claim 10 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2021
From: PEDROSA MARTINS, TERESA PATRICIA; ALVES REIS, MARIANA; DA COSTA LEAO, PEDRO NUNO; OLIVEIRA VASCONCELOS, VITOR MANUEL; HASSOUANI, MERYEM; SABOUR, BRAHIM
To: CIIMAR - CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL; UNIVERSIDADE DO PORTO; FACULTY OF SCIENCES, CHOUAIB DOUKKALI UNIVERSITY
Reel/Frame 056819/0357 →
Priority Claims (1)
PT 115227 · Dec 21, 2018 · national
Continuity (1)
Related Publication 20220331218A1 · Oct 20, 2022
References Cited (5)
US 5498405A · Gerwick et al. · 1996 [cited by applicant]
US 6787147B1 · Huner · 2004 [cited by examiner]
Swain et al. (“Antibacterial, antifungal and antimycobacterial compounds from cyanobacteria”, Biomedicine & Pharmacotherapy, vol. 90, 2017, pp. 760-776) (Year: 2017). [cited by examiner]
C.S. Grant, et al; Scytonemin-imine, a mahogany-colored UV/Vis sunscreen of cyanobacteria exposed to intense solar radiation; Organic Geochemistry; vol. 65; Dec. 1, 2013; pp. 29-36; XP055683143. [cited by applicant]
International Search Report and Written Opinion for corresponding application PCT/EP2020/050025 dated Apr. 30, 2020. [cited by applicant]