Granted Patent B2

US 12,236,581 · App. 16/953,027 · Granted Feb 25, 2025

Inventor: David J Minion (Lexington, KY)

Assignee: University of Kentucky Research Foundation

G06T7/0012A61F2/07G06T7/13G06T2207/20041G06T2207/20081G06T2207/30101

Abstract

Claims (40)

1. A method of anatomic classification of aorta anatomy in aortic aneurysms to determine a number of seal segments between the aorta and an endograft implanted within the aorta, the method comprising:

accessing an image of an aorta;

analyzing the image to identify a point of divergence of the aorta and one or more additional points of reference of the aorta, the point of divergence defined as a point along a centerline of the aorta where a contour of the aorta changes from a cylindrical or conical shape to a reverse conical shape, and the one or more additional points of reference including a location of a lowest preserved branch vessel and a location of where a proximal end of an endograft would be upon implantation within the aorta;

measuring one or more longitudinal distances along the centerline of the aorta between the point of divergence of the aorta and at least one of the one or more additional points of reference; and

classifying the aneurysm based upon the measured distances to determine a number of seal segments between the aorta and the endograft upon implantation within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to both the point of divergence and the location of the lowest preserved branch vessel, there are three possible seal segments between the aorta and the endograft upon implantation within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to only one of the point of divergence and the location of the lowest preserved branch vessel, there are two possible seal segments between the aorta and the endograft upon implantation within the aorta; and

wherein, when the location of the proximal end of the endograft is distal to both the point of divergence and the location of the lowest preserved branch vessel, there is one possible seal segment between the aorta and the endograft upon implantation within the aorta.

2. The method of claim 1 , wherein the one or more additional points of reference includes at least one of: (i) an origin of the aorta, (ii) a terminus of the aorta, (iii) a location of one or more branch vessels, (iv) a point of threshold diameter of the aorta, (v) a point of restriction of the aorta, (vi) a point of maximum diameter of the aorta, and (vii) a point of convergence of the aorta.

3. The method of claim 2 , wherein one of the one or more distances measured is a distance between the point of divergence of the aorta and the location of the lowest preserved branch vessel.

4. The method of claim 2 , wherein one of the one or more distances measured is a distance between the point of divergence of the aorta and the point of threshold diameter of the aorta.

5. The method of claim 2 , wherein the classification of the aneurysm includes identifying the following segments of the aorta:

a seal zone proximal to the point of divergence;

a sub-seal zone distal to the point of divergence, but proximal to the point of threshold diameter of the aorta; and

an aneurysm sac distal to the point of threshold diameter of the aorta.

6. The method of claim 5 , wherein the classification of the aneurysm further includes determining which of the segments of the aorta contains the lowest preserved branch vessel.

7. The method of claim 1 , wherein the image is further analyzed to identify a location of where an end of apposition of the endograft would be upon implantation within the aorta.

8. The method of claim 7 , wherein the threshold diameter of the aorta is a maximum diameter of therapeutic effectiveness of the endograft.

9. The method of claim 7 , wherein the threshold diameter of the aorta is a maximum diameter of the endograft.

10. The method of claim 1 , wherein one of the one or more distances measured is a distance between the location of the proximal end of the endograft and the location of the lowest preserved branch vessel.

11. The method of claim 1 , wherein one of the one or more distances measured is a distance between the point of divergence of the aorta and a point where a diameter of the aorta is a maximum diameter of therapeutic effectiveness of the endograft.

12. A system for anatomic classification of aorta anatomy in aortic aneurysms to determine a number of seal segments between the aorta and an endograft implanted within the aorta, comprising:

a data receiving module for receiving an image of an aorta; and

an analysis module for

i. analyzing the image to identify a point of divergence of the aorta and one or more additional points of reference of the aorta, the point of divergence defined as a point along a centerline of the aorta where a contour of the aorta changes from a cylindrical or conical shape to a reverse conical shape, and the one or more additional points of reference including a location of a lowest preserved branch vessel and a location of where a proximal end of an endograft would be upon implantation within the aorta,

ii. measuring one or more longitudinal distances along the centerline of the aorta between the point of divergence of the aorta and at least one of the one or more additional points of reference, and

iii. classifying the aneurysm based upon the measured distances to determine a number of seal segments between the aorta and the endograft upon implantation within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to both the point of divergence and the location of the lowest preserved branch vessel, there are three possible seal segments between the aorta and the endograft upon implantation within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to only one of the point of divergence and the location of the lowest preserved branch vessel, there are two possible seal segments between the aorta and the endograft upon implantation within the aorta; and

wherein, when the location of the proximal end of the endograft is distal to both the point of divergence and the location of the lowest preserved branch vessel, there is one possible seal segment between the aorta and the endograft upon implantation within the aorta.

13. A method of using objective points of reference for the anatomic classification of aortic aneurysms to guide therapy based upon a number of seal segments between the aorta and an endograft implanted within the aorta, the method comprising:

accessing an image of an aorta;

analyzing the image to identify objective points of reference including a point of divergence of the aorta and one or more additional points of reference of the aorta, the point of divergence defined as a point along the centerline of the aorta where a contour of the aorta changes from a cylindrical or conical shape to a reverse conical shape, and the one or more additional points of reference including a location of a lowest preserved branch vessel and a location of where a proximal end of an endograft would be upon implantation within the aorta;

measuring one or more longitudinal distances along the centerline of the aorta between the point of divergence of the aorta and at least one of the one or more additional points of reference;

classifying the aneurysm based upon the measured distances to determine a number of seal segments between the aorta and the endograft upon implantation within the aorta; and

developing a treatment strategy based upon the number of seal segments between the aorta and an endograft implanted within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to both the point of divergence and the location of the lowest preserved branch vessel, there are three possible seal segments between the aorta and the endograft upon implantation within the aorta;

wherein, when the location of the proximal end of the endograft is proximal to only one of the point of divergence and the location of the lowest preserved branch vessel, there are two possible seal segments between the aorta and the endograft upon implantation within the aorta; and

wherein, when the location of the proximal end of the endograft is distal to both the point of divergence and the location of the lowest preserved branch vessel, there is one possible seal segment between the aorta and the endograft upon implantation within the aorta.

14. The method of claim 13 , wherein developing the treatment strategy includes choosing a parallel graft configured for treatment of the aneurysm.

Assignments (1)

Continuity (2)

References Cited (13)