Devices, systems, and methods for vessel assessment and intervention recommendation
Devices, systems, and methods of evaluating risk associated with a condition of the vessel and providing an objective intervention recommendation based on the evaluated risk are disclosed. The method includes steps of obtaining physiologic measurements from a first instrument and a second instrument positioned within the vessel of the patient while the second instrument is moved longitudinally through the vessel from a first position to a second position, obtaining image data from an image of a vessel system, co-registering the physiologic measurements with the image data to produce co-registered physiologic measurements, and determining whether to perform a first surgical procedure or a second surgical procedure, wherein the determining is based on the co-registered physiologic measurements. Other associated methods, systems, and devices are also provided herein.
1. A system, comprising:
a pressure-sensing guidewire configured to be positioned within a vessel of a patient, wherein the pressure-sensing guidewire comprises a proximal portion, a distal portion, and a pressure sensor coupled to the distal portion; and
a processor configured for communication with the pressure-sensing guidewire, wherein the processor is configured to:
obtain a plurality of pressure measurements from the pressure-sensing guidewire at a plurality of locations along the vessel and a pressure-sensing instrument;
determine, based on the plurality of pressure measurements, a plurality of pressure ratios corresponding to the plurality of locations;
obtain an external image of the vessel;
co-register the plurality of pressure ratios with the plurality of locations in the external image;
determine, using a disease quantification score (DSQ) calculator, a total DSQ associated with the vessel, wherein the total DSQ [score] comprises a first contribution from a first segment of the vessel and a second contribution from a second segment of the vessel;
generate a pressure-based view of the external image based on the plurality of pressure ratios, wherein the pressure-based view comprises a plurality of pressure ratio markers distributed along the vessel in the external image at the corresponding plurality of locations;
generate a DSQ-based view of the external image based on the total DSQ, wherein the DSQ-based view comprises:
the external image; and
a first numerical value of the first contribution overlaid on the external image at a first location of the vessel specific to the first segment; and
output, to a display in communication with the processor, a user interface comprising:
an external image area comprising one of the pressure-based view or the DSQ-based view; and
a numerical value of the total DSQ.
2. The system of claim 1 , wherein the numerical value of the total DSQ is displayed proximate to the external image area in the user interface when the external image area comprises the pressure-based view and when the external image area comprises the DSQ-based view.
3. The system of claim 1 , wherein the user interface further comprises a view button for the external image area.
4. The system of claim 1 , wherein the DSQ-based view comprises further comprises a second numerical value of the second contribution overlaid on the external image at a second location of the vessel specific to the second segment.
5. The system of claim 1 , wherein the pressure-based view comprises a visual representation of the plurality of pressure ratios in the external image.
6. The system of claim 5 , wherein the visual representation of the plurality of pressure ratios corresponds to the plurality of pressure ratio markers.
7. The system of claim 1 , wherein the total DSQ comprises an image-based DSQ.
8. The system of claim 7 ,
wherein the processor is configured to calculate a total functional DSQ associated with the vessel, and
wherein the user interface further comprises a visual representation of the total functional DSQ.
9. The system of claim 8 ,
wherein the image-based DSQ comprises a SYNTAX score, and
wherein the total functional DSQ comprises a functional SYNTAX score.
10. The system of claim 8 ,
wherein the total functional DSQ comprises a third contribution from the first segment of the vessel,
wherein the DSQ-based view further comprises a third numerical value of the third contribution overlaid on the external image at the first location of the vessel specific to the first segment.
11. The system of claim 3 , wherein the view button is displayed proximate to the external image area in the user interface.
12. The system of claim 3 , wherein the processor is further configured to receive a user input on the view button to switch the external image area to the other of the pressure-based view or the DSQ-based view.
13. The system of claim 3 , wherein the view button is displayed in the user interface when the external image area comprises the pressure-based view and when the external image area comprises the DSQ-based view.
14. The system of claim 1 , wherein the plurality of locations along the vessel are representative of movement of the pressure-sensing guidewire through the vessel.
15. The system of claim 14 , wherein the first segment is predefined by the DSQ calculator such that the first location is distinct from the plurality of locations.
16. The system of claim 10 , wherein the first numerical value comprises a first visual appearance and the third numerical value comprises a second visual appearance distinguishable from the first visual appearance.
17. The system of claim 16 , wherein the first visual appearance comprises a first shape and the second visual appearance comprises a different, second shape.