IP Library › Granted Patent US 12,251,208
Granted Patent B2
US 12,251,208 · App. 17/106,302 · Granted Mar 18, 2025

Time controlled medication

Inventors: Uri Kartoun (Cambridge, MA); Zachary A. Silverstein (Austin, TX); Sarbajit K. Rakshit (Kolkata, IN)
Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
A61B5/07A61K9/2086A61M31/002B01J13/04B01J13/22G16H20/10A61B2562/162A61J3/007A61M2205/18A61M2205/3553
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Quick Facts
Patent No.
US 12,251,208
App. No.
17/106,302
Granted
Mar 18, 2025
Kind
B2
Abstract

A method, a computer program product, and a computer system provide medications to a patient with a time gap. The method includes determining a dissolving pattern for the patient. The dissolving pattern includes a medication dissolving rate for a first medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to a second medication being provided after the first medication. The medication dissolving rate and the filler dissolving rate are specific to the patient. The method includes determining dimensions of the first medication to correspond to a dosage of the prescribed first medication and dimensions of the filler to correspond to the time gap. The method includes providing a pill including at least the first medication and the filler, the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved.

Claims (28)

1. A computer-implemented method for providing medications to a patient with a time gap, the method comprising:

determining a dissolving pattern for the patient, the dissolving pattern including a medication dissolving rate for a first medication and a second medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to the second medication being taken after the first medication, the medication dissolving rate and the filler dissolving rate being specific to the patient;

determining dimensions of the first medication and the second medication to correspond to a dosage of the prescribed first medication and the prescribed second medication, respectively, and dimensions of the filler to accomplish the time gap; and

based on determining a combination of the dimensions of the first medication, the second medication, and the filler contained in a multi-medication pill exceed a maximum pill size threshold for the patient, 3D printing a signal pill including at least the first medication, the filler, and an edible electronic circuit (EEC), the filler surrounding the EEC and the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved, the first medication and the filler 3D printed in accordance with the determined dimensions.

2. The computer-implemented method of claim 1 , wherein the pill is a multi-medication pill, the multi-medication pill including the second medication, the second medication being surrounded by the filler.

3. The computer-implemented method of claim 1 , wherein, after the filler has been dissolved to expose the EEC, the EEC is powered to transmit a signal, the signal configured to provide an alert to the patient that the time gap has elapsed.

4. The computer-implemented method of claim 3 , wherein the EEC is piezoelectric such that exposure to stomach acid from the patient powers the EEC.

5. The computer-implemented method of claim 1 , wherein determining the dissolving pattern is performed during a trial run, the trial run including providing a first monitoring pill including the first medication and a medication monitoring embedded circuit, an exposure of the medication monitoring embedded circuit generating a signal that is transmitted to define a medication time duration for the patient to dissolve the first medication, the trial run including providing a second monitoring pill including the filler and a filler monitoring embedded circuit, a further exposure of the filler monitoring embedded circuit generating a further signal that is transmitted to define a filler time duration for the patient to dissolve the filler.

6. The computer-implemented method of claim 1 , wherein the time gap prevents a drug interaction between the first medication and the second medication.

7. A computer program product for providing medications to a patient with a time gap, the computer program product comprising:

one or more non-transitory computer-readable storage media and program instructions stored on the one or more non-transitory computer-readable storage media capable of performing a method, the method comprising:

determining a dissolving pattern for the patient, the dissolving pattern including a medication dissolving rate for a first medication and a second medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to the second medication being taken after the first medication, the medication dissolving rate and the filler dissolving rate being specific to the patient;

determining dimensions of the first medication and the second medication to correspond to a dosage of the prescribed first medication and the prescribed second medication, respectively, and dimensions of the filler to accomplish the time gap; and

based on determining a combination of the dimensions of the first medication, the second medication, and the filler contained in a multi-medication pill exceed a maximum pill size threshold for the patient, 3D printing a signal pill including at least the first medication, the filler, and an edible electronic circuit (EEC), the filler surrounding the EEC and the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved, the first medication and the filler 3D printed in accordance with the determined dimensions.

8. The computer program product of claim 7 , wherein the pill is a multi-medication pill, the multi-medication pill including the second medication, the second medication being surrounded by the filler.

9. The computer program product of claim 7 , wherein, after the filler has been dissolved to expose the EEC, the EEC is powered to transmit a signal, the signal configured to provide an alert to the patient that the time gap has elapsed.

10. The computer program product of claim 9 , wherein the EEC is piezoelectric such that exposure to stomach acid from the patient powers the EEC.

11. The computer program product of claim 7 , wherein determining the dissolving pattern is performed during a trial run, the trial run including providing a first monitoring pill including the first medication and a medication monitoring embedded circuit, an exposure of the medication monitoring embedded circuit generating a signal that is transmitted to define a medication time duration for the patient to dissolve the first medication, the trial run including providing a second monitoring pill including the filler and a filler monitoring embedded circuit, a further exposure of the filler monitoring embedded circuit generating a further signal that is transmitted to define a filler time duration for the patient to dissolve the filler.

12. The computer program product of claim 7 , wherein the time gap prevents a drug interaction between the first medication and the second medication.

13. A computer system for providing medications to a patient with a time gap, the computer system comprising:

one or more computer processors, one or more computer-readable storage media, and program instructions stored on the one or more of the computer-readable storage media for execution by at least one of the one or more processors capable of performing a method, the method comprising:

determining a dissolving pattern for the patient, the dissolving pattern including a medication dissolving rate for a first medication and a second medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to the second medication being taken after the first medication, the medication dissolving rate and the filler dissolving rate being specific to the patient;

determining dimensions of the first medication and the second medication to correspond to a dosage of the prescribed first medication and the prescribed second medication, respectively, and dimensions of the filler to accomplish the time gap; and

based on determining a combination of the dimensions of the first medication, the second medication, and the filler contained in a multi-medication pill exceed a maximum pill size threshold for the patient, 3D printing a signal pill including at least the first medication, the filler, and an edible electronic circuit (EEC), the filler surrounding the EEC and the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved, the first medication and the filler 3D printed in accordance with the determined dimensions.

14. The computer system of claim 13 , wherein the pill is a multi-medication pill, the multi-medication pill including the second medication, the second medication being surrounded by the filler.

15. The computer system of claim 13 , wherein, after the filler has been dissolved to expose the EEC, the EEC is powered to transmit a signal, the signal configured to provide an alert to the patient that the time gap has elapsed.

16. The computer system of claim 15 , wherein the EEC is piezoelectric such that exposure to stomach acid from the patient powers the EEC.

17. The computer system of claim 13 , wherein determining the dissolving pattern is performed during a trial run, the trial run including providing a first monitoring pill including the first medication and a medication monitoring embedded circuit, an exposure of the medication monitoring embedded circuit generating a signal that is transmitted to define a medication time duration for the patient to dissolve the first medication, the trial run including providing a second monitoring pill including the filler and a filler monitoring embedded circuit, a further exposure of the filler monitoring embedded circuit generating a further signal that is transmitted to define a filler time duration for the patient to dissolve the filler.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 30, 2020
From: KARTOUN, URI; SILVERSTEIN, ZACHARY A.; RAKSHIT, SARBAJIT K.
To: INTERNATIONAL BUSINESS MACHINES CORPORATION
Reel/Frame 054486/0212 →
Continuity (1)
Related Publication 20220168551A1 · Jun 2, 2022
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