IP Library › Granted Patent US 12,253,456
Granted Patent B2
US 12,253,456 · App. 18/072,655 · Granted Mar 18, 2025

Microfluidic detection device

Inventors: Shu-Jiang Liu (Hsinchu, TW); Chun-Cheng Hung (Hsinchu, TW); Wen-Jen Li (Hsinchu, TW); Zhi-Jain Yu (Hsinchu, TW); Han-Chung Lai (Hsinchu, TW)
Assignee: AUO Corporation
G01N21/0303B01L3/502715G02B6/43G01N2201/0668G01N2201/0873
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Quick Facts
Patent No.
US 12,253,456
App. No.
18/072,655
Granted
Mar 18, 2025
Kind
B2
Abstract

Disclosed is a microfluidic detection device including a circuit substrate and a transparent substrate. The circuit substrate is provided with at least one first light-emitting device used to emit a detection beam, a photodetector used to receive the detection beam and send out a sensing signal, and a control circuit electrically connected to the first light-emitting device and the photodetector. The transparent substrate overlaps the circuit substrate and is provided with a microfluidic channel and a light guide structure. The light guide structure has a light incident surface disposed corresponding to the first light-emitting device and a light exiting surface disposed corresponding to the photodetector. The light guide structure extends from each of the light incident surface and the light exiting surface to the microfluidic channel and is adapted to transmit the detection beam into and out of the microfluidic channel.

Claims (18)

1. A microfluidic detection device comprising:

a circuit substrate provided with:

at least one first light-emitting device used to emit a detection beam;

a photodetector used to receive the detection beam and send out a sensing signal; and

a control circuit electrically connected to the at least one first light-emitting device and the photodetector; and

a transparent substrate overlapping the circuit substrate and being provided with:

a microfluidic channel; and

a light guide structure having a light incident surface and a light exiting surface, the light guide structure is surrounded by the transparent substrate, the light guide structure extending from each of the light incident surface to the microfluidic channel, and the light guide structure extending from the light exiting surface to the microfluidic channel, and the light guide structure adapted to transmit the detection beam into and out of the microfluidic channel, wherein the light incident surface of the light guide structure is disposed corresponding to the at least one first light-emitting device, and the light exiting surface of the light guide structure is disposed corresponding to the photodetector.

2. The microfluidic detection device according to claim 1 , wherein the transparent substrate is further provided with a display area, the circuit substrate is further provided with a plurality of second light-emitting devices, and the second light-emitting devices overlap the display area.

3. The microfluidic detection device according to claim 2 , wherein the control circuit is further adapted to control the second light-emitting devices to emit light to display a process result of the sensing signal from the photodetector.

4. The microfluidic detection device according to claim 1 , wherein a refractive index of the light guide structure is greater than a refractive index of the transparent substrate.

5. The microfluidic detection device according to claim 1 , wherein the control circuit is adapted to control microfluidics to move in the microfluidic channel.

6. The microfluidic detection device according to claim 5 , wherein the control circuit is further adapted to receive the sensing signal from the photodetector.

7. The microfluidic detection device according to claim 1 , wherein the transparent substrate is further provided with at least one microcavity in communication with the microfluidic channel.

8. The microfluidic detection device according to claim 1 , wherein a material of the transparent substrate comprises glass, polycarbonate, polymethylmethacrylate, or a cyclo olefin polymer.

9. The microfluidic detection device according to claim 1 , wherein the microfluidic channel has a first end surface and a second end surface facing each other, the transparent substrate has a substrate surface facing the circuit substrate, the light guide structure comprises a first waveguide and a second waveguide, the first waveguide extends in a bent manner from the substrate surface to the first end surface of the microfluidic channel, and the second waveguide extends in a bent manner from the substrate surface to the second end surface of the microfluidic channel.

10. The microfluidic detection device according to claim 1 , wherein the transparent substrate has a substrate surface facing the circuit substrate, and the substrate surface is coplanar with the light incident surface and the light exiting surface of the light guide structure.

11. The microfluidic detection device according to claim 1 , wherein the at least one first light-emitting device comprises a plurality of first light-emitting devices, and the first light-emitting devices are adapted to emit light of different colors or fluorescent light.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2022
From: LIU, SHU-JIANG; HUNG, CHUN-CHENG; LI, WEN-JEN; YU, ZHI-JAIN; LAI, HAN-CHUNG
To: AUO CORPORATION
Reel/Frame 062018/0974 →
Priority Claims (1)
TW 111128888 · Aug 2, 2022 · national
Continuity (1)
Related Publication 20240044776A1 · Feb 8, 2024
References Cited (35)
US 5858195A · Ramsey · 1999 [cited by applicant]
US 6001229A · Ramsey · 1999 [cited by applicant]
US 6010607A · Ramsey · 2000 [cited by applicant]
US 6010608A · Ramsey · 2000 [cited by applicant]
US 6033546A · Ramsey · 2000 [cited by applicant]
US 6342142B1 · Ramsey · 2002 [cited by applicant]
US 6469785B1 · Duveneck et al. · 2002 [cited by applicant]
US 6475363B1 · Ramsey · 2002 [cited by applicant]
US 8541168B1 · Wohlstadter · 2013 [cited by examiner]
US 11175467B2 · Meng et al. · 2021 [cited by applicant]
US 20020008030A1 · Ramsey · 2002 [cited by applicant]
US 20030150733A1 · Ramsey · 2003 [cited by applicant]
US 20030205469A1 · Ramsey · 2003 [cited by applicant]
US 20030205470A1 · Ramsey · 2003 [cited by applicant]
US 20030226753A1 · Ramsey · 2003 [cited by applicant]
US 20030226755A1 · Ramsey · 2003 [cited by applicant]
US 20040007464A1 · Ramsey · 2004 [cited by applicant]
US 20040009517A1 · Ramsey · 2004 [cited by applicant]
US 20040115861A1 · Wong · 2004 [cited by examiner]
US 20040137445A1 · Ramsey · 2004 [cited by applicant]
US 20100152066A1 · Malik · 2010 [cited by examiner]
US 20200233158A1 · Meng · 2020 [cited by examiner]
US 20210229096A1 · Lin · 2021 [cited by examiner]
US 20210354128A1 · Meng · 2021 [cited by examiner]
CN 1052301 · 2000 [cited by applicant]
CN 107607475A · 2018 [cited by examiner]
CN 109632660 · 2019 [cited by applicant]
CN 109632660A · 2019 [cited by examiner]
CN 107607475B · 2020 [cited by examiner]
CN 108956467B · 2022 [cited by examiner]
EP 3299800A1 · 2018 [cited by examiner]
JP 2000516719A · 2000 [cited by examiner]
JP 2004333250A · 2004 [cited by examiner]
WO WO2011136265A1 · 2011 [cited by examiner]
WO WO2019228035A1 · 2019 [cited by examiner]