IP Library › Granted Patent US 12,268,443
Granted Patent B2
US 12,268,443 · App. 18/376,322 · Granted Apr 8, 2025

Therapeutic laser system and method of use for activating the tissue stem cell niche for the treatment of medical conditions

Inventors: Pamela Joy Barton (Osprey, FL); Bruno Gerald Frenguelli (Kenilworth, GB); Frank Joseph Rauscher, III (Wayne, PA)
Assignee: KAIROS LASERS LLC
A61B18/203A61B18/22A61B2018/00327A61B2018/00458A61B2018/0047A61B2018/00565A61B2018/00702A61B2018/00714A61B2560/02
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Quick Facts
Patent No.
US 12,268,443
App. No.
18/376,322
Granted
Apr 8, 2025
Kind
B2
Abstract

A system for treating various medical conditions in humans includes a medical or therapeutic laser operating at wavelengths in the near infrared range of between 1250 nm-1267 nm, with a target wavelength of 1260 nm, at power levels between 2 Watts and 60 Watts, and for a period not to exceed 60 seconds per dose. The emitted laser light energizes, e.g., the stem cell niche or mitochondria of the human tissue to which it is applied, both directly and indirectly via activation of cell signaling intermediaries including but not limited to heat shock proteins, thereby stimulating cell activity to promote healing and reduce pain. In this specific wavelength range, water absorption of the laser light energy is plateaued which effectively acts as a conduit allowing the laser light energy to be transferred deeper into the tissue without causing thermal damage to the skin and tissue.

Claims (10)

1. A method for treating a condition in a human or an animal using a laser, the method comprising the steps of:

applying a laser beam emitted from the laser to a particular site on the skin of the human or the animal at a distance up to 10 inches from the skin at the particular site, the applied laser beam having a wavelength of 1260 nanometers (nm) and a power setting between 2 Watts and 60 Watts;

maintaining the applied laser beam at the particular site on the skin until there is up to a 10-degree Fahrenheit (° F.) increase in temperature at the particular site on the skin;

maintaining the temperature increase of up to 10° F. at the particular site on the skin for a period of at least 45 seconds and not more than 60 seconds, thereby allowing for an irradiance and power density of the applied laser beam of greater than 1.0 Watts per centimeter squared (W/cm 2 ) and less than 2.25 W/cm 2 at the particular site on the skin for a period of 45 seconds to 60 seconds

wherein the step of applying the laser beam to a particular site on the skin further comprises:

applying the laser beam to the particular site on the skin that either shows some overt sign of damage or for which there is reasonable belief that it is indicative of some degree of damage to underlying body tissue or bone; and

applying the laser beam to a plurality of different spaced apart locations on the skin in the vicinity of the particular site, thereby allowing the applied laser beam to access the stem cell niche immediately proximal to the area of the particular site which provides for energetic activation of the stem cell niche and its contents;

wherein the particular site on the skin is in the vicinity of a joint of the human or the animal, and wherein the step of applying a laser beam emitted from the laser to a particular site on the skin of the human or the animal comprises applying the laser beam to the particular site at a power setting between 30 Watts and 40 Watts; and

wherein the joint comprises a knee of the human or the animal, and wherein the step of applying a laser beam emitted from the laser to a particular site on the skin of the human or the animal comprises applying the laser beam to a front portion of the knee and a back portion of the knee.

2. The method of claim 1 , wherein the stem cell niche includes a water rich hydrophobic environment, wherein energy from the applied laser beam is absorbed by the water rich hydrophobic environment in the stem cell niche, and wherein by the applied laser beam absorption an energy gradient is created resulting in the mitochondria from the cells directly receiving the laser energy, and/or adjacent cells, are stimulated to emit cytokines resulting in an activation of the stem cell niche and causing the transportation of mitochondrial signals from healthy tissue to unhealthy tissue.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 22, 2023
From: BARTON, PAMELA JOY; FRENGUELLI, BRUNO GERLAD; RAUSHER, FRANK JOSEPH, III
To: KAIROS LASERS LLC
Reel/Frame 065939/0555 →
Continuity (2)
Provisional Application 63412726 · Oct 3, 2022
Related Publication 20240108407A1 · Apr 4, 2024
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