IP Library › Granted Patent US 12,268,598
Granted Patent B2
US 12,268,598 · App. 17/337,711 · Granted Apr 8, 2025

Mechanically expandable prosthetic heart valve and delivery apparatus

Inventors: Hanoch Cohen-Tzemach (Holon, IL); Tamir S. Levi (Zikhron Yaakov, IL); Yair A. Neumann (Moshav Sede Varburg, IL); Tomer Saar (Pardes Hanna-Karkur, IL); Gregory Rinberg (Haifa, IL)
Assignee: EDWARDS LIFESCIENCES CORPORATION
A61F2/243A61F2/2418A61F2/2439A61F2230/0091
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Quick Facts
Patent No.
US 12,268,598
App. No.
17/337,711
Granted
Apr 8, 2025
Kind
B2
Abstract

A radially expandable prosthetic valve can comprise an annular frame, at least one expansion mechanism and a cord. The annular frame can be radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The expansion mechanism can comprise a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location. The cord can extend at least partially along the expansion mechanism in a first direction, be reeved around a portion of the second member, and extend at least partially along the expansion mechanism in a second direction opposite the first direction. Applying a proximally directed force to a first portion of the cord can cause the second member to move relative to the first member, which can cause the frame to foreshorten axially and expand radially.

Claims (42)

1. A radially expandable prosthetic valve, comprising:

an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration;

at least one expansion mechanism comprising a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location;

a cord that extends through a first opening in the second member, extends at least partially along the second member in a first direction, is reeved around a cord routing member of the second member, extends at least partially along the second member in a second direction opposite the first direction, and extends through a second opening in the second member; and

wherein the cord routing member is spaced apart in an axial direction from both the first opening and the second opening, and

wherein applying a proximally directed force to a first portion of the cord causes the cord to move relative to the second member and the second member to move relative to the first member, which causes the frame to foreshorten axially and expand radially.

2. The prosthetic valve of claim 1 ,

wherein applying a proximally directed force to a second portion of the cord releases the cord from the expansion mechanism.

3. The prosthetic valve of claim 1 , further comprising a stop member coupled to the cord and sized to prevent the cord from being pulled through the expansion mechanism when the proximally directed force is applied to the first portion of the cord.

4. The prosthetic valve of claim 3 , wherein the stop member comprises a knot.

5. The prosthetic valve of claim 1 , wherein the expansion mechanism further comprises a housing and the second member is slidable at least partially within the housing.

6. The prosthetic valve of claim 5 , wherein the cord extends through a first portion of the housing, around the portion of the second member and through a second portion of the housing, in that order.

7. The prosthetic valve of claim 6 , wherein applying the proximally directed force to the first portion of the cord pulls the second member through the housing towards the first location on the frame.

8. The prosthetic valve of claim 1 , further comprising a locking mechanism configured to retain the frame in the radially expanded configuration.

9. The prosthetic valve of claim 1 , wherein the at least one expansion mechanism comprises a ratchet assembly.

10. The prosthetic valve of claim 9 , wherein the first member comprises one of a rack and a pawl of the ratchet assembly and the second member comprises the other of the rack and the pawl of the ratchet assembly.

11. The prosthetic valve of claim 10 , wherein the rack comprises an elongated bar comprising a plurality of ratchet teeth arrayed along a length of the bar;

wherein the rack is movable with respect to the pawl;

wherein applying the proximally directed force to the first portion of the cord causes the rack to move in the second direction thereby causing the annular frame to foreshorten axially and expand radially; and

wherein engagement of the pawl with one of the ratchet teeth prevents movement of the rack in the first direction to prevent radial compression of the annular frame.

12. The prosthetic valve of claim 11 , wherein the pawl comprises an engagement portion that is configured to engage the ratchet teeth of the rack, a release portion extending away from the rack, and an intermediate portion between the engagement portion and the release portion, wherein an inwardly directed radial force applied to the release portion causes the engagement portion to disengage from the ratchet teeth to allow movement of the pawl along the rack in the first direction.

13. The prosthetic valve of claim 12 , wherein the cord is a first cord and the prosthetic valve further comprises a second cord connected to the release portion of the pawl such that a pulling force applied to the second cord causes the engagement portion to disengage from the ratchet teeth.

14. The prosthetic valve of claim 13 , wherein the second cord comprises a loop that extends through first and second openings in the release portion of the pawl.

15. The prosthetic valve of claim 13 , wherein the at least one expansion mechanism comprises at least two expansion mechanisms and the second cord of each expansion mechanism is configured such that a pulling force applied to the second cord of each expansion mechanism causes the frame to compress radially.

16. The prosthetic valve of claim 1 , wherein the frame comprises a plurality of struts connected to each other at a plurality of pivot joints and the second member comprises a post that extends into openings in two of the struts to form one of the pivot joints.

17. The prosthetic valve of claim 10 , wherein the expansion mechanism further comprises a retaining member configured to apply a biasing force to the pawl so as to resiliently retain the pawl in engagement with the rack.

18. The prosthetic valve of claim 1 , wherein the cord is reeved is a pulley of the cord routing member.

19. The prosthetic valve of claim 1 , wherein the cord is a suture.

20. The prosthetic valve of claim 13 , wherein the second cord is a suture.

21. The prosthetic valve of claim 1 , in combination with a delivery apparatus comprising a handle, wherein the first portion of the cord is operatively connected to the handle.

22. The prosthetic valve of claim 1 , wherein the expansion mechanism further comprises a biasing member configured to exert a biasing force against the second member in the second direction, wherein the biasing force is selected such that when the prosthetic valve is implanted within a native heart valve annulus, the second member is caused to move in the second direction under the biasing force and further expand the frame as the native annulus enlarges over time.

23. The prosthetic valve of claim 22 , wherein the biasing member comprises a spring.

24. A radially expandable prosthetic valve, comprising:

an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration;

at least one expansion mechanism comprising a first member attached to the frame at a first location and a second member attached to the frame at a second location axially spaced from the first location;

a cord operatively connected to the first and second members,

wherein the cord extends through a first opening in the second member, extends at least partially along the second member in a first direction, is reeved around a cord routing member of the second member, extends at least partially along the second member in a second direction opposite the first direction, and extends through a second opening in the second member, such that applying a force to the cord causes the second member to move relative to the first member with a mechanical advantage greater than 1,

wherein movement of the second member relative to the first member causes the frame to radially expand, and

wherein the cord routing member is spaced apart in an axial direction from both the first opening and the second opening; and

a knot coupled to the cord and sized to prevent the cord from being pulled through the expansion mechanism when a proximally directed force is applied to the cord.

25. The prosthetic valve of claim 24 , wherein the mechanical advantage is at least 2:1.

26. The prosthetic valve of claim 24 , wherein the cord extends distally at least partially along the expansion mechanism, around a portion of the second member, and proximally at least partially along the expansion mechanism.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2021
From: COHEN-TZEMACH, HANOCH; LEVI, TAMIR S.; NEUMANN, YAIR A.; SAAR, TOMER; RINBERG, GREGORY
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 056554/0292 →
Continuity (3)
Continuation PCTUS2019064373 · Dec 4, 2019
Provisional Application 62776348 · Dec 6, 2018
Related Publication 20210282922A1 · Sep 16, 2021
References Cited (389)
US 3409013A · Berry · 1968 [cited by applicant]
US 3548417A · Kisher · 1970 [cited by applicant]
US 3587115A · Shiley · 1971 [cited by applicant]
US 3657744A · Ersek · 1972 [cited by applicant]
US 3671979A · Moulopoulos · 1972 [cited by applicant]
US 3714671A · Edwards et al. · 1973 [cited by applicant]
US 3755823A · Hancock · 1973 [cited by applicant]
US 4035849A · Angell et al. · 1977 [cited by applicant]
US 4056854A · Boretos et al. · 1977 [cited by applicant]
US 4106129A · Carpentier et al. · 1978 [cited by applicant]
US 4222126A · Boretos et al. · 1980 [cited by applicant]
US 4265694A · Boretos et al. · 1981 [cited by applicant]
US 4297749A · Davis et al. · 1981 [cited by applicant]
US RE30912E · Hancock · 1982 [cited by applicant]
US 4339831A · Johnson · 1982 [cited by applicant]
US 4343048A · Ross et al. · 1982 [cited by applicant]
US 4345340A · Rosen · 1982 [cited by applicant]
US 4373216A · Klawitter · 1983 [cited by applicant]
US 4406022A · Roy · 1983 [cited by applicant]
US 4441216A · Ionescu et al. · 1984 [cited by applicant]
US 4470157A · Love · 1984 [cited by applicant]
US 4535483A · Klawitter et al. · 1985 [cited by applicant]
US 4574803A · Storz · 1986 [cited by applicant]
US 4592340A · Boyles · 1986 [cited by applicant]
US 4605407A · Black et al. · 1986 [cited by applicant]
US 4612011A · Kautzky · 1986 [cited by applicant]
US 4643732A · Pietsch et al. · 1987 [cited by applicant]
US 4655771A · Wallsten · 1987 [cited by applicant]
US 4692164A · Dzemeshkevich et al. · 1987 [cited by applicant]
US 4733665A · Palmaz · 1988 [cited by applicant]
US 4759758A · Gabbay · 1988 [cited by applicant]
US 4762128A · Rosenbluth · 1988 [cited by applicant]
US 4777951A · Cribier et al. · 1988 [cited by applicant]
US 4787899A · Lazarus · 1988 [cited by applicant]
US 4787901A · Baykut · 1988 [cited by applicant]
US 4796629A · Grayzel · 1989 [cited by applicant]
US 4820299A · Philippe et al. · 1989 [cited by applicant]
US 4829990A · Thuroff et al. · 1989 [cited by applicant]
US 4851001A · Taheri · 1989 [cited by applicant]
US 4856516A · Hillstead · 1989 [cited by applicant]
US 4878495A · Grayzel · 1989 [cited by applicant]
US 4878906A · Lindemann et al. · 1989 [cited by applicant]
US 4883458A · Shiber · 1989 [cited by applicant]
US 4922905A · Strecker · 1990 [cited by applicant]
US 4966604A · Reiss · 1990 [cited by applicant]
US 4979939A · Shiber · 1990 [cited by applicant]
US 4986830A · Owens et al. · 1991 [cited by applicant]
US 4994077A · Dobben · 1991 [cited by applicant]
US 5007896A · Shiber · 1991 [cited by applicant]
US 5026366A · Leckrone · 1991 [cited by applicant]
US 5032128A · Alonso · 1991 [cited by applicant]
US 5037434A · Lane · 1991 [cited by applicant]
US 5047041A · Samuels · 1991 [cited by applicant]
US 5059177A · Towne et al. · 1991 [cited by applicant]
US 5080668A · Bolz et al. · 1992 [cited by applicant]
US 5085635A · Cragg · 1992 [cited by applicant]
US 5089015A · Ross · 1992 [cited by applicant]
US 5152771A · Sabbaghian et al. · 1992 [cited by applicant]
US 5163953A · Vince · 1992 [cited by applicant]
US 5167628A · Boyles · 1992 [cited by applicant]
US 5192297A · Hull · 1993 [cited by applicant]
US 5266073A · Wall · 1993 [cited by applicant]
US 5282847A · Trescony et al. · 1994 [cited by applicant]
US 5295958A · Shturman · 1994 [cited by applicant]
US 5332402A · Teitelbaum · 1994 [cited by applicant]
US 5360444A · Kusuhara · 1994 [cited by applicant]
US 5370685A · Stevens · 1994 [cited by applicant]
US 5397351A · Pavcnik et al. · 1995 [cited by applicant]
US 5411055A · Kane · 1995 [cited by applicant]
US 5411552A · Andersen et al. · 1995 [cited by applicant]
US 5443446A · Shturman · 1995 [cited by applicant]
US 5480424A · Cox · 1996 [cited by applicant]
US 5500014A · Quijano et al. · 1996 [cited by applicant]
US 5545209A · Roberts et al. · 1996 [cited by applicant]
US 5545214A · Stevens · 1996 [cited by applicant]
US 5549665A · Vesely et al. · 1996 [cited by applicant]
US 5554185A · Block et al. · 1996 [cited by applicant]
US 5558644A · Boyd et al. · 1996 [cited by applicant]
US 5571175A · Vanney et al. · 1996 [cited by applicant]
US 5584803A · Stevens et al. · 1996 [cited by applicant]
US 5591185A · Kilmer et al. · 1997 [cited by applicant]
US 5591195A · Taheri et al. · 1997 [cited by applicant]
US 5607464A · Trescony et al. · 1997 [cited by applicant]
US 5609626A · Quijano et al. · 1997 [cited by applicant]
US 5628792A · Lentell · 1997 [cited by applicant]
US 5639274A · Fischell et al. · 1997 [cited by applicant]
US 5665115A · Cragg · 1997 [cited by applicant]
US 5716417A · Girard et al. · 1998 [cited by applicant]
US 5728068A · Leone et al. · 1998 [cited by applicant]
US 5749890A · Shaknovich · 1998 [cited by applicant]
US 5756476A · Epstein et al. · 1998 [cited by applicant]
US 5769812A · Stevens et al. · 1998 [cited by applicant]
US 5800508A · Goicoechea et al. · 1998 [cited by applicant]
US 5840081A · Andersen et al. · 1998 [cited by applicant]
US 5855597A · Jayaraman · 1999 [cited by applicant]
US 5855601A · Bessler et al. · 1999 [cited by applicant]
US 5855602A · Angell · 1999 [cited by applicant]
US 5925063A · Khosravi · 1999 [cited by applicant]
US 5957949A · Leonhardt et al. · 1999 [cited by applicant]
US 6027525A · Suh et al. · 2000 [cited by applicant]
US 6132473A · Williams et al. · 2000 [cited by applicant]
US 6168614B1 · Andersen et al. · 2001 [cited by applicant]
US 6171335B1 · Wheatley et al. · 2001 [cited by applicant]
US 6174327B1 · Mertens et al. · 2001 [cited by applicant]
US 6210408B1 · Chandrasekaran et al. · 2001 [cited by applicant]
US 6217585B1 · Houser et al. · 2001 [cited by applicant]
US 6221091B1 · Khosravi · 2001 [cited by applicant]
US 6231602B1 · Carpentier et al. · 2001 [cited by applicant]
US 6245102B1 · Jayaraman · 2001 [cited by applicant]
US 6299637B1 · Shaolian et al. · 2001 [cited by applicant]
US 6302906B1 · Goicoechea et al. · 2001 [cited by applicant]
US 6338740B1 · Carpentier · 2002 [cited by applicant]
US 6350277B1 · Kocur · 2002 [cited by applicant]
US 6352547B1 · Brown et al. · 2002 [cited by applicant]
US 6425916B1 · Garrison et al. · 2002 [cited by applicant]
US 6440764B1 · Focht et al. · 2002 [cited by applicant]
US 6454799B1 · Schreck · 2002 [cited by applicant]
US 6458153B1 · Bailey et al. · 2002 [cited by applicant]
US 6461382B1 · Cao · 2002 [cited by applicant]
US 6468660B2 · Ogle et al. · 2002 [cited by applicant]
US 6482228B1 · Norred · 2002 [cited by applicant]
US 6488704B1 · Connelly et al. · 2002 [cited by applicant]
US 6527979B2 · Constantz et al. · 2003 [cited by applicant]
US 6569196B1 · Vesely · 2003 [cited by applicant]
US 6582462B1 · Andersen et al. · 2003 [cited by applicant]
US 6605112B1 · Moll et al. · 2003 [cited by applicant]
US 6652578B2 · Bailey et al. · 2003 [cited by applicant]
US 6689123B2 · Pinchasik · 2004 [cited by applicant]
US 6716244B2 · Klaco · 2004 [cited by applicant]
US 6730118B2 · Spenser et al. · 2004 [cited by applicant]
US 6733525B2 · Yang et al. · 2004 [cited by applicant]
US 6767362B2 · Schreck · 2004 [cited by applicant]
US 6769161B2 · Brown et al. · 2004 [cited by applicant]
US 6783542B2 · Eidenschink · 2004 [cited by applicant]
US 6830584B1 · Seguin · 2004 [cited by applicant]
US 6878162B2 · Bales et al. · 2005 [cited by applicant]
US 6893460B2 · Spenser et al. · 2005 [cited by applicant]
US 6908481B2 · Cribier · 2005 [cited by applicant]
US 6936067B2 · Buchanan · 2005 [cited by applicant]
US 7018406B2 · Seguin et al. · 2006 [cited by applicant]
US 7018408B2 · Bailey et al. · 2006 [cited by applicant]
US 7096554B2 · Austin et al. · 2006 [cited by applicant]
US 7225518B2 · Eidenschink et al. · 2007 [cited by applicant]
US 7276078B2 · Spenser et al. · 2007 [cited by applicant]
US 7276084B2 · Yang et al. · 2007 [cited by applicant]
US 7316710B1 · Cheng et al. · 2008 [cited by applicant]
US 7318278B2 · Zhang et al. · 2008 [cited by applicant]
US 7374571B2 · Pease et al. · 2008 [cited by applicant]
US 7393360B2 · Spenser et al. · 2008 [cited by applicant]
US 7462191B2 · Spenser et al. · 2008 [cited by applicant]
US 7510575B2 · Spenser et al. · 2009 [cited by applicant]
US 7563280B2 · Anderson et al. · 2009 [cited by applicant]
US 7585321B2 · Cribier · 2009 [cited by applicant]
US 7618446B2 · Andersen et al. · 2009 [cited by applicant]
US 7618447B2 · Case et al. · 2009 [cited by applicant]
US 7655034B2 · Mitchell et al. · 2010 [cited by applicant]
US 7785366B2 · Maurer et al. · 2010 [cited by applicant]
US 7959665B2 · Pienknagura · 2011 [cited by applicant]
US 7959672B2 · Salahieh et al. · 2011 [cited by applicant]
US 7993394B2 · Hariton et al. · 2011 [cited by applicant]
US 8029556B2 · Rowe · 2011 [cited by applicant]
US 8075611B2 · Millwee et al. · 2011 [cited by applicant]
US 8128686B2 · Paul, Jr. et al. · 2012 [cited by applicant]
US 8167932B2 · Bourang et al. · 2012 [cited by applicant]
US 8291570B2 · Fidenschink et al. · 2012 [cited by applicant]
US 8348998B2 · Pintor et al. · 2013 [cited by applicant]
US 8449606B2 · Eliasen et al. · 2013 [cited by applicant]
US 8454685B2 · Hariton et al. · 2013 [cited by applicant]
US 8652203B2 · Quadri et al. · 2014 [cited by applicant]
US 8685055B2 · VanTassel et al. · 2014 [cited by applicant]
US 8747463B2 · Fogarty et al. · 2014 [cited by applicant]
US 9078781B2 · Ryan et al. · 2015 [cited by applicant]
US 20010021872A1 · Bailey et al. · 2001 [cited by applicant]
US 20020026094A1 · Roth · 2002 [cited by applicant]
US 20020032481A1 · Gabbay · 2002 [cited by applicant]
US 20020138135A1 · Duerig et al. · 2002 [cited by applicant]
US 20020143390A1 · Ishii · 2002 [cited by applicant]
US 20020173842A1 · Buchanan · 2002 [cited by applicant]
US 20030014105A1 · Cao · 2003 [cited by applicant]
US 20030040791A1 · Oktay · 2003 [cited by applicant]
US 20030050694A1 · Yang et al. · 2003 [cited by applicant]
US 20030100939A1 · Yodfat et al. · 2003 [cited by applicant]
US 20030158597A1 · Quiachon et al. · 2003 [cited by applicant]
US 20030212454A1 · Scott et al. · 2003 [cited by applicant]
US 20040024452A1 · Kruse et al. · 2004 [cited by applicant]
US 20040039436A1 · Spenser et al. · 2004 [cited by applicant]
US 20040078074A1 · Anderson et al. · 2004 [cited by applicant]
US 20040186558A1 · Pavcnik et al. · 2004 [cited by applicant]
US 20040186563A1 · Lobbi · 2004 [cited by applicant]
US 20040186565A1 · Schreck · 2004 [cited by applicant]
US 20040260389A1 · Case et al. · 2004 [cited by applicant]
US 20050010285A1 · Lambrecht et al. · 2005 [cited by applicant]
US 20050075725A1 · Rowe · 2005 [cited by applicant]
US 20050075728A1 · Nguyen et al. · 2005 [cited by applicant]
US 20050096736A1 · Osse et al. · 2005 [cited by applicant]
US 20050096738A1 · Cali et al. · 2005 [cited by applicant]
US 20050137686A1 · Salahieh et al. · 2005 [cited by applicant]
US 20050188525A1 · Weber et al. · 2005 [cited by applicant]
US 20050203614A1 · Forster et al. · 2005 [cited by applicant]
US 20050203617A1 · Forster et al. · 2005 [cited by applicant]
US 20050234546A1 · Nugent et al. · 2005 [cited by applicant]
US 20060004469A1 · Sokel · 2006 [cited by applicant]
US 20060025857A1 · Bergheim et al. · 2006 [cited by applicant]
US 20060058872A1 · Salahieh et al. · 2006 [cited by applicant]
US 20060074484A1 · Huber · 2006 [cited by applicant]
US 20060108090A1 · Ederer et al. · 2006 [cited by applicant]
US 20060149350A1 · Patel et al. · 2006 [cited by applicant]
US 20060183383A1 · Asmus et al. · 2006 [cited by applicant]
US 20060229719A1 · Marquez et al. · 2006 [cited by applicant]
US 20060259136A1 · Nguyen et al. · 2006 [cited by applicant]
US 20060259137A1 · Artof et al. · 2006 [cited by applicant]
US 20060287717A1 · Rowe et al. · 2006 [cited by applicant]
US 20070005131A1 · Taylor · 2007 [cited by applicant]
US 20070010876A1 · Salahieh et al. · 2007 [cited by applicant]
US 20070010877A1 · Salahieh et al. · 2007 [cited by applicant]
US 20070112355A1 · Salahieh et al. · 2007 [cited by applicant]
US 20070112422A1 · Dehdashtian · 2007 [cited by applicant]
US 20070162102A1 · Ryan et al. · 2007 [cited by applicant]
US 20070203503A1 · Salahieh · 2007 [cited by examiner]
US 20070203575A1 · Forster et al. · 2007 [cited by applicant]
US 20070203576A1 · Lee et al. · 2007 [cited by applicant]
US 20070208550A1 · Cao et al. · 2007 [cited by applicant]
US 20070213813A1 · Von Segesser et al. · 2007 [cited by applicant]
US 20070233228A1 · Eberhardt et al. · 2007 [cited by applicant]
US 20070260305A1 · Drews et al. · 2007 [cited by applicant]
US 20070265700A1 · Eliasen et al. · 2007 [cited by applicant]
US 20080021546A1 · Patz et al. · 2008 [cited by applicant]
US 20080114442A1 · Mitchell et al. · 2008 [cited by applicant]
US 20080125853A1 · Bailey et al. · 2008 [cited by applicant]
US 20080154355A1 · Benichou et al. · 2008 [cited by applicant]
US 20080183271A1 · Frawley et al. · 2008 [cited by applicant]
US 20080208327A1 · Rowe · 2008 [cited by applicant]
US 20080243245A1 · Thambar et al. · 2008 [cited by applicant]
US 20080255660A1 · Guyenot et al. · 2008 [cited by applicant]
US 20080275537A1 · Limon · 2008 [cited by applicant]
US 20080294248A1 · Yang et al. · 2008 [cited by applicant]
US 20090118826A1 · Khaghani · 2009 [cited by applicant]
US 20090125118A1 · Gong · 2009 [cited by applicant]
US 20090157175A1 · Benichou · 2009 [cited by applicant]
US 20090276040A1 · Rowe et al. · 2009 [cited by applicant]
US 20090281619A1 · Le et al. · 2009 [cited by applicant]
US 20090287296A1 · Manasse · 2009 [cited by applicant]
US 20090287299A1 · Tabor et al. · 2009 [cited by applicant]
US 20090299452A1 · Eidenschink et al. · 2009 [cited by applicant]
US 20090319037A1 · Rowe et al. · 2009 [cited by applicant]
US 20100004735A1 · Yang et al. · 2010 [cited by applicant]
US 20100049313A1 · Alon et al. · 2010 [cited by applicant]
US 20100082094A1 · Quadri et al. · 2010 [cited by applicant]
US 20100100176A1 · Elizondo et al. · 2010 [cited by applicant]
US 20100168844A1 · Toomes et al. · 2010 [cited by applicant]
US 20100185277A1 · Braido et al. · 2010 [cited by applicant]
US 20100198347A1 · Zakay et al. · 2010 [cited by applicant]
US 20100204781A1 · Alkhatib · 2010 [cited by applicant]
US 20110015729A1 · Jimenez et al. · 2011 [cited by applicant]
US 20110022157A1 · Essinger et al. · 2011 [cited by applicant]
US 20110066224A1 · White · 2011 [cited by applicant]
US 20110137397A1 · Chau et al. · 2011 [cited by applicant]
US 20110218619A1 · Benichou et al. · 2011 [cited by applicant]
US 20110319991A1 · Hariton et al. · 2011 [cited by applicant]
US 20120030090A1 · Johnston et al. · 2012 [cited by applicant]
US 20120089223A1 · Nguyen et al. · 2012 [cited by applicant]
US 20120101571A1 · Thambar et al. · 2012 [cited by applicant]
US 20120123529A1 · Levi et al. · 2012 [cited by applicant]
US 20120259409A1 · Nguyen et al. · 2012 [cited by applicant]
US 20130023985A1 · Khairkhahan et al. · 2013 [cited by applicant]
US 20130046373A1 · Cartledge et al. · 2013 [cited by applicant]
US 20130150956A1 · Yohanan et al. · 2013 [cited by applicant]
US 20130166017A1 · Cartledge et al. · 2013 [cited by applicant]
US 20130190857A1 · Mitra et al. · 2013 [cited by applicant]
US 20130274873A1 · Delaloye et al. · 2013 [cited by applicant]
US 20130310926A1 · Hariton · 2013 [cited by applicant]
US 20130317598A1 · Rowe et al. · 2013 [cited by applicant]
US 20130331929A1 · Mitra et al. · 2013 [cited by applicant]
US 20140194981A1 · Menk et al. · 2014 [cited by applicant]
US 20140200661A1 · Pintor et al. · 2014 [cited by applicant]
US 20140209238A1 · Bonyuet et al. · 2014 [cited by applicant]
US 20140222136A1 · Geist et al. · 2014 [cited by applicant]
US 20140277417A1 · Schraut et al. · 2014 [cited by applicant]
US 20140277419A1 · Garde et al. · 2014 [cited by applicant]
US 20140277424A1 · Oslund · 2014 [cited by applicant]
US 20140277563A1 · White · 2014 [cited by applicant]
US 20140296962A1 · Cartledge · 2014 [cited by examiner]
US 20140330368A1 · Gloss · 2014 [cited by examiner]
US 20140330372A1 · Weston et al. · 2014 [cited by applicant]
US 20140343670A1 · Bakis et al. · 2014 [cited by applicant]
US 20140343671A1 · Yohanan et al. · 2014 [cited by applicant]
US 20140350667A1 · Braido et al. · 2014 [cited by applicant]
US 20150073545A1 · Braido · 2015 [cited by applicant]
US 20150073546A1 · Braido · 2015 [cited by applicant]
US 20150135506A1 · White · 2015 [cited by applicant]
US 20150157455A1 · Hoang et al. · 2015 [cited by applicant]
US 20160256271A1 · Backus · 2016 [cited by examiner]
US 20160374802A1 · Levi et al. · 2016 [cited by applicant]
US 20170014229A1 · Nguyen-Thien-Nhon et al. · 2017 [cited by applicant]
US 20180028310A1 · Gurovich et al. · 2018 [cited by applicant]
US 20180153689A1 · Maimon et al. · 2018 [cited by applicant]
US 20180325665A1 · Gurovich et al. · 2018 [cited by applicant]
US 20180344456A1 · Barash et al. · 2018 [cited by applicant]
US 20190159894A1 · Levi et al. · 2019 [cited by applicant]
US 20190192288A1 · Levi et al. · 2019 [cited by applicant]
US 20190192289A1 · Levi et al. · 2019 [cited by applicant]
CN 107645941A · 2018 [cited by applicant]
DE 0144167C · 1903 [cited by applicant]
DE 2246526A1 · 1973 [cited by applicant]
DE 19532846A1 · 1997 [cited by applicant]
DE 19546692A1 · 1997 [cited by applicant]
DE 19857887A1 · 2000 [cited by applicant]
DE 19907646A1 · 2000 [cited by applicant]
DE 10049812A1 · 2002 [cited by applicant]
DE 10049813C1 · 2002 [cited by applicant]
DE 10049814A1 · 2002 [cited by applicant]
DE 10049815A1 · 2002 [cited by applicant]
EP 0103546A1 · 1984 [cited by applicant]
EP 0850607A1 · 1998 [cited by applicant]
EP 1057460A1 · 2000 [cited by applicant]
EP 1088529A2 · 2001 [cited by applicant]
EP 1570809A1 · 2005 [cited by applicant]
FR 2788217A1 · 2000 [cited by applicant]
FR 2815844A1 · 2002 [cited by applicant]
GB 2056023A · 1981 [cited by applicant]
SU 1271508A1 · 1986 [cited by applicant]
WO 9117720A1 · 1991 [cited by applicant]
WO 9217118A1 · 1992 [cited by applicant]
WO 9301768A1 · 1993 [cited by applicant]
WO 9724080A1 · 1997 [cited by applicant]
WO 9829057A1 · 1998 [cited by applicant]
WO 9930646A1 · 1999 [cited by applicant]
WO 9933414A1 · 1999 [cited by applicant]
WO 9940964A1 · 1999 [cited by applicant]
WO 9947075A1 · 1999 [cited by applicant]
WO 0018333A1 · 2000 [cited by applicant]
WO 0041652A1 · 2000 [cited by applicant]
WO 0135878A2 · 2001 [cited by applicant]
WO 0149213A2 · 2001 [cited by applicant]
WO 0154624A1 · 2001 [cited by applicant]
WO 0154625A1 · 2001 [cited by applicant]
WO 0162189A1 · 2001 [cited by applicant]
WO 0047139A9 · 2001 [cited by applicant]
WO 0164137A1 · 2001 [cited by applicant]
WO 0176510A2 · 2001 [cited by applicant]
WO 0222054 · 2002 [cited by applicant]
WO 0236048A1 · 2002 [cited by applicant]
WO 0241789A2 · 2002 [cited by applicant]
WO 0243620A1 · 2002 [cited by applicant]
WO 0247575A2 · 2002 [cited by applicant]
WO 0249540A2 · 2002 [cited by applicant]
WO 03047468 · 2003 [cited by applicant]
WO 2005034812A1 · 2005 [cited by applicant]
WO 2005055883A1 · 2005 [cited by applicant]
WO 2005084595A1 · 2005 [cited by applicant]
WO 2006014233A2 · 2006 [cited by applicant]
WO 2006032051A2 · 2006 [cited by applicant]
WO 2006034008A2 · 2006 [cited by applicant]
WO 2006111391A1 · 2006 [cited by applicant]
WO 2006127089A1 · 2006 [cited by applicant]
WO 2006138173A2 · 2006 [cited by applicant]
WO 2005102015A3 · 2007 [cited by applicant]
WO 2007047488A2 · 2007 [cited by applicant]
WO 2007067942A1 · 2007 [cited by applicant]
WO 2007097983A2 · 2007 [cited by applicant]
WO 2008005405A2 · 2008 [cited by applicant]
WO 2008015257A2 · 2008 [cited by applicant]
WO 2008035337A2 · 2008 [cited by applicant]
WO 2008091515A2 · 2008 [cited by applicant]
WO 2008147964A1 · 2008 [cited by applicant]
WO 2008150529A1 · 2008 [cited by applicant]
WO 2009033469A1 · 2009 [cited by applicant]
WO 2009042196A2 · 2009 [cited by applicant]
WO 2009053497A1 · 2009 [cited by applicant]
WO 2009061389A2 · 2009 [cited by applicant]
WO 2009094188A2 · 2009 [cited by applicant]
WO 2009116041A2 · 2009 [cited by applicant]
WO 2009149462A2 · 2009 [cited by applicant]
WO 2010121076A2 · 2010 [cited by applicant]
WO 2013106585A1 · 2013 [cited by applicant]
WO 2015085218A1 · 2015 [cited by applicant]
H.R. Andersen, et al. “Transluminal Implantation of Artificial Heart Valve. Description of a New Expandable Aortic Valve and Initial Results with implantation by Catheter Technique in Closed Chest Pig,” European Heart J… [cited by applicant]
H.R. Andersen “History of Percutaneous Aortic Valve Prosthesis,” Herz No. 34. pp. 343-346. 2009. [cited by applicant]
Pavcnik, et al. “Development and initial Experimental Evaluation of a Prosthetic Aortic Valve for Transcatheter Placement,” Cardiovascular Radiology, vol. 183, No. 1. pp. 151-154. 1992. [cited by applicant]
Bailey, S. “Percutaneous Expandable Prosthetic Valves,” Textbook of Interventional Cardiology vol. 2, 2nd Ed. pp. 1268-1276. 1994. [cited by applicant]
Al-Khaja, et al. “Eleven Years' Experience with Carpentier-Edwards Biological Valves in Relation to Survival and Complications,” European Journal of Cardiothoracic Surgery, vol. 3. pp. 305-311. 1989. [cited by applicant]
Ross, “Aortic Valve Surgery,” At a meeting of the Council on Aug. 4, 1966. pp. 192-197. [cited by applicant]
Sabbah, et al. “Mechanical Factors in the Degeneration of Porcine Bioprosthetic Valves: An Overview,” Journal of Cardiac Surgery, vol. 4, No. 4. pp. 302-309. 1989. [cited by applicant]
Wheatley, “Valve Prostheses,” Operative Surgery, 4th ed. pp. 415-424. 1986. [cited by applicant]
Uchida, “Modifications of Gianturco Expandable Wire Stents,” American Journal of Roentgenology, vol. 150. pp. 1185-1187. 1986. [cited by applicant]
Walther T, Dehdashtian MM, Khanna R, Young E, Goldbrunner PJ, Lee W. Trans-catheter valve-in-valve implantation: in vitro hydrodynamic performance of the SAPIEN+cloth trans-catheter heart valve in the Carpentier-Edwards… [cited by applicant]
Fontaine, M.D., Arthur B., et al., “Vascular Stent Prototype; Results of Preclinical Evaluation”, p. 29-34; Technical Developments and Instrumentation; Jan.-Feb. 1996, vol. 7, No. 1. [cited by applicant]
Fontaine, M.D., Arthur B., et al., “Prototype Stent: Invivo Swine Studies in the Biliary System1”, p. 101-105, Journal of Vascular and Interventional Radiology; Jan.-Feb. 1997; vol. 8, No. 1. [cited by applicant]
Patrick W. Serruys, Nicolo Piazza, Alain Cribier, John Webb, Jean-Claude Laborde, Peter de Jaegere, “Transcatheter Aortic Valve Implantation: Tips and Tricks to Avoid Failure”; we file the table of contents and pp. 18 t… [cited by applicant]
Cited By (3)
US 12,514,700 US 12,616,569 US 12,685,635