Drug delivery device with drive sub-assembly
The present disclosure relates to a drive subassembly for a drug delivery device, the drive subassembly comprising a housing and a plunger, wherein the plunger is adapted to be rotated between a locked position, in which the plunger is prevented from advancing, and a released position, in which the plunger is advancable, wherein at least one restraining component is provided to restrain rotation of the plunger from the locked position towards the released position.
1. A drug delivery device comprising:
a drive subassembly comprising a housing and a plunger, wherein the plunger is adapted to be rotated between a locked position, in which the plunger is prevented from advancing, and a released position, in which the plunger is advanceable,
at least one restraining component adapted to restrain rotation of the plunger from the locked position towards the released position, and
a control subassembly comprising a distal region of the housing adapted to receive a syringe and a sleeve coupled to the housing to permit movement of the sleeve relative to the housing to release the plunger;
wherein the at least one restraining component comprises a plunger boss on the plunger and an indent in the housing, the plunger boss having a proximal boss protruding in a proximal direction adapted to be received within the indent to restrain rotation of the plunger from the locked position towards the released position.
2. The drug delivery device of claim 1 , further comprising the syringe containing a medicament.
3. The drug delivery device of claim 1 , wherein the at least one restraining component is configured to restrain rotation of the plunger from the locked position towards the released position during a priming step.
4. The drug delivery device of claim 1 , wherein the at least one restraining component comprises a deformable housing protrusion on the housing and a plunger boss or edge on the plunger adapted to:
abut the housing protrusion when the plunger is rotated from the locked position towards the released position, and
deform the housing protrusion upon further rotation of the plunger towards the released position.
5. The drug delivery device of claim 4 , wherein the housing protrusion is configured to protrude radially inwards or in a distal direction.
6. The drug delivery device of claim 4 , wherein the plunger boss is resiliently or plastically deformable.
7. The drug delivery device of claim 4 , wherein the plunger boss comprises a radial plunger protrusion adapted to abut the housing protrusion.
8. The drug delivery device of claim 4 , wherein a plunger protrusion or the plunger boss comprises a chamfer adapted to engage the housing protrusion when the plunger is rotated from the released position towards the locked position.
9. The drug delivery device of claim 4 , wherein the edge is arranged on a recess within a proximal face of the plunger.
10. The drug delivery device of claim 1 , wherein the at least one restraining component comprises a transversal component and a plunger boss on the plunger adapted to abut the transversal component when in the locked position and being moved in a proximal direction to restrain proximal movement of the plunger.
11. The drug delivery device of claim 10 , wherein the transversal component is a housing beam comprising a fixed end coupled to the housing and a free end, the free end comprising a distal protrusion adapted to abut the plunger boss upon rotation of the plunger from the locked position towards the released position.
12. The drug delivery device of claim 11 , wherein the housing beam is resiliently or plastically deformable.
13. The drug delivery device of claim 11 , wherein the distal protrusion comprises a chamfer adapted to engage the plunger boss when the plunger is rotated from the released position towards the locked position.
14. The drug delivery device of claim 10 , wherein the transversal component comprises at least one rounded or chamfered edge to engage the plunger boss.
15. The drug delivery device of claim 10 , wherein the transversal component is axially positioned to allow an axial clearance between the plunger boss and the transversal component when the plunger is being moved out of the locked position.
16. The drug delivery device of claim 1 , wherein the indent comprises a ramp adapted to guide a proximal boss of the plunger boss into the indent and rotate the plunger towards the locked position.
17. The drug delivery device of claim 1 , wherein a ramp is provided on the housing adapted to engage the plunger during assembly of the plunger into the housing and to rotate the plunger towards the locked position upon movement of the plunger in a proximal direction relative to the housing.
18. The drug delivery device of claim 1 , further comprising a drive spring adapted to bias the plunger in a distal direction relative to the housing.
19. The drug delivery device of claim 1 , wherein the sleeve comprises a sleeve rib having a longitudinal face interacting with a plunger boss,
wherein, as the sleeve is being moved from an extended position towards a retracted position, the plunger boss moves relative to the sleeve in a distal direction guided along the longitudinal face of the sleeve rib until the plunger boss has moved distally beyond the sleeve rib such that the plunger is no longer prevented from rotating in a first rotational direction.
20. A drug delivery device comprising:
a drive subassembly comprising a housing and a plunger, wherein the plunger is adapted to be rotated between a locked position, in which the plunger is prevented from advancing, and a released position, in which the plunger is advanceable,
at least one restraining component adapted to restrain rotation of the plunger from the locked position towards the released position, and a control subassembly comprising a distal region of the housing adapted to receive a syringe and a sleeve coupled to the housing to permit movement of the sleeve relative to the housing to release the plunger,
wherein the at least one restraining component comprises a plunger boss on the plunger and an indent in the housing,
wherein the indent is formed at a proximal end of a profiled slot in the housing, and
wherein the plunger boss has a proximal boss adapted to be received within the indent.
21. The drug delivery device of claim 1 , wherein the proximal boss protrudes from the plunger boss.