Granted Patent B2

US 12,274,884 · App. 17/955,478 · Granted Apr 15, 2025

Inventors: Michael L. Ellingson (St. Louis Park, MN); Hyun J. Yoon (Vadnais Heights, MN)

Assignee: Medtronic, Inc.

A61N1/3718A61N1/37254A61N1/3688

Abstract

Claims (90)

1. A method comprising:

automatically determining, with a first device, one or more parameters of an exposure operating mode based on at least one of stored information related to sensed physiological events and/or stored information related to therapy provided over a predetermined period time by:

analyzing a PAV interval measured during the predetermined period of time, wherein the stored information includes the PAV interval measured during the predetermined period of time; and

selecting a PAV interval as one of the parameters to be implemented during the exposure operating mode based on the analysis;

after automatically determining the one or more parameters of the exposure operating mode, storing the automatically determined parameters of the exposure operating mode in a memory;

switching operation of an implantable medical device from parameters of a current operating mode to the one or more automatically determined parameters of the exposure operating mode; and

delivering therapy by the implantable medical device implementing the one or more automatically determined parameters of the exposure operating mode.

2. The method of claim 1 , wherein analyzing the PAV interval includes analyzing an average PAV interval measured during the predetermined period of time, the stored information includes the average PAV interval measured during the predetermined period of time, and selecting the PAV interval to be implemented during the exposure mode based on the analysis includes selecting based on the analysis of the average PAV interval measured during the predetermined period of time.

3. The method of claim 2 , wherein selecting the PAV interval to be implemented during the exposure mode based on the analysis further comprises:

selecting a first fixed PAV interval when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a first PAV interval threshold;

selecting the average PAV interval measured during the predetermined period of time when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a second PAV interval threshold, and less than the first PAV interval threshold; and

selecting a second fixed PAV interval when the average PAV interval measured during the predetermined period of time is less than the second PAV interval threshold.

4. The method of claim 3 , wherein the first fixed PAV interval is approximately one hundred and ten milliseconds, the first PAV interval threshold is approximately one hundred and ten milliseconds, the second fixed PAV interval is approximately fifty milliseconds, and the second PAV interval threshold is approximately fifty milliseconds.

5. The method of claim 1 , wherein automatically determining the one or more parameters of the exposure operating mode further comprises:

analyzing a maximum pacing amplitude measured during the predetermined period of time, wherein the stored information includes the maximum pacing amplitude measured during the predetermined period of time;

selecting a pacing amplitude to be delivered during the exposure operating mode as a fixed pacing amplitude when the maximum pacing amplitude measured during the predetermined period of time is less than a maximum pacing amplitude threshold; and

selecting the pacing amplitude to be delivered during the exposure operating mode as the maximum pacing amplitude measured during the predetermined period of time when the maximum pacing amplitude measured during the predetermined period of time is approximately equal to or greater than the maximum pacing amplitude threshold measured during the predetermined period of time,

wherein the fixed pacing amplitude is approximately five volts, and the maximum pacing amplitude threshold is approximately five volts.

6. The method of claim 1 , wherein automatically determining the one or more parameters of the exposure operating mode further comprises:

analyzing a maximum pacing pulse width measured during the predetermined period of time, wherein the stored information includes the maximum pacing pulse width measured during the predetermined period of time;

selecting a pacing pulse width to be delivered during the exposure operating mode as a fixed pacing pulse width when the maximum pacing width measured during the predetermined period of time is less than a maximum pacing pulse width threshold; and

selecting the pacing pulse width to be delivered during the exposure operating mode

as the maximum pulse width measured during the predetermined period of time when the maximum pacing pulse width is approximately equal to or greater than the maximum pacing pulse width threshold,

wherein the fixed pacing pulse width is approximately one millisecond, and the maximum pacing pulse width threshold is approximately one millisecond.

7. The method of claim 1 , wherein the first device is the implantable medical device.

8. An implantable medical device comprising:

a memory; and

a processor configured for:

automatically determining one or more parameters of an exposure operating mode based on at least one of stored information related to sensed physiological events and/or stored information related to therapy provided over a predetermined period time by:

analyzing a PAV interval measured during the predetermined period of time, wherein the stored information includes the PAV interval measured during the predetermined period of time; and

selecting a PAV interval to be implemented during the exposure operating mode based on the analysis;

after automatically determining the one or more parameters of the exposure operating mode, storing the automatically determined parameters of the exposure operating mode in the memory;

switching operation of the implantable medical device from parameters of a current operating mode to the one or more automatically determined parameters of the exposure operating mode; and

delivering therapy by implementing the one or more automatically determined parameters of the exposure operating mode.

9. The device of claim 8 , wherein analyzing the PAV interval includes analyzing an average PAV interval measured during the predetermined period of time, the stored information includes the average PAV interval measured during the predetermined period of time, and the processor is further configured for:

selecting the PAV interval to be implemented during the exposure operating mode as a first fixed PAV interval when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a first PAV interval threshold;

selecting the PAV interval to be implemented during the exposure operating mode as the average PAV interval measured during the predetermined period of time when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a second PAV interval threshold, and less than the first PAV interval threshold; and

selecting the PAV interval to be implemented during the exposure operating mode as a second fixed PAV interval when the average PAV interval measured during the predetermined period of time is less than the second PAV interval threshold,

wherein the first fixed PAV interval is approximately one hundred and ten milliseconds, the first PAV interval threshold is approximately one hundred and ten milliseconds, the second fixed PAV interval is approximately fifty milliseconds, and the second PAV interval threshold is approximately fifty milliseconds.

10. The device of claim 8 , further configured for:

analyzing a maximum pacing amplitude and a maximum pacing pulse width measured during the predetermined period of time, wherein the stored information includes the maximum pacing amplitude and the maximum pacing pulse width measured during the predetermined period of time;

selecting a pacing amplitude to be delivered during the exposure operating mode as a fixed pacing amplitude when the maximum pacing amplitude measured during the predetermined period of time is less than a maximum pacing amplitude threshold;

selecting the pacing amplitude to be delivered during the exposure operating mode as the maximum pacing amplitude measured during the predetermined period of time when the maximum pacing amplitude measured during the predetermined period of time is approximately equal to or greater than the maximum pacing amplitude threshold measured during the predetermined period of time;

selecting a pacing pulse width to be delivered during the exposure operating mode as a fixed pacing pulse width when the maximum pacing width measured during the predetermined period of time is less than a maximum pacing pulse width threshold; and

selecting the pacing pulse width to be delivered during the exposure operating mode as the maximum pulse width measured during the predetermined period of time when maximum pacing pulse width is approximately equal to or greater than the maximum pacing pulse width threshold,

wherein the fixed pacing amplitude is approximately five volts, the maximum pacing amplitude threshold is approximately five volts, the fixed pacing pulse width is approximately one millisecond, and the maximum pacing pulse width threshold is approximately one millisecond.

11. A method comprising:

automatically determining, with a first device, one or more parameters of an exposure operating mode based on at least one of stored information related to sensed physiological events and/or stored information related to therapy provided over a predetermined period time by:

analyzing at least one of a maximum pacing amplitude and/or a maximum pacing pulse width measured during the predetermined period of time, wherein the stored information includes the maximum pacing amplitude and/or the maximum pacing pulse width measured during the predetermined period of time; and

selecting at least one of a pacing amplitude and/or pacing pulse width to be delivered during the exposure operating mode based on the analysis;

after automatically determining the one or more parameters of the exposure operating mode, storing the automatically determined parameters of the exposure operating mode in a memory;

switching operation of an implantable medical device from parameters of a current operating mode to the one or more automatically determined parameters of the exposure operating mode; and

delivering therapy by the implantable medical device implementing the one or more automatically determined parameters of the exposure operating mode.

12. The method of claim 11 , wherein selecting the pacing amplitude and/or pacing pulse width to be delivered during the exposure operating mode further comprises:

selecting the pacing amplitude as a fixed pacing amplitude when the maximum pacing amplitude measured during the predetermined period of time is less than a maximum pacing amplitude threshold; and

selecting the pacing amplitude as the maximum pacing amplitude measured during the predetermined period of time when the maximum pacing amplitude measured during the predetermined period of time is approximately equal to or greater than the maximum pacing amplitude threshold measured during the predetermined period of time.

13. The method of claim 12 , wherein the fixed pacing amplitude is approximately five volts, and the maximum pacing amplitude threshold is approximately five volts.

14. The method of claim 11 , wherein automatically determining the one or more parameters of the exposure operating mode further comprises:

analyzing an average PAV interval measured during the predetermined period of time, wherein the stored information includes the average PAV interval measured during the predetermined period of time;

selecting a PAV interval to be implemented during the exposure operating mode as a first fixed PAV interval when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a first PAV interval threshold;

selecting the PAV interval to be implemented during the exposure operating mode as the average PAV interval measured during the predetermined period of time when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a second PAV interval threshold, and less than the first PAV interval threshold; and

selecting the PAV interval to be implemented during the exposure operating mode as a second fixed PAV interval when the average PAV interval measured during the predetermined period of time is less than the second PAV interval threshold,

wherein the first fixed PAV interval is approximately one hundred and 10 milliseconds, the first PAV interval threshold is approximately one hundred and 10 milliseconds, the second fixed PAV interval is approximately fifty milliseconds, and the second PAV interval threshold is approximately fifty milliseconds.

15. The method of claim 11 , wherein selecting the pacing pulse width to be implemented during the exposure mode based on the analysis further comprises:

selecting the pacing pulse width as a fixed pacing pulse width when the maximum pacing pulse width measured during the predetermined period of time is less than a maximum pacing pulse width threshold; and

selecting the pacing pulse width as maximum pulse width measured during the predetermined period of time when maximum pacing pulse width is approximately equal to or greater than the maximum pacing pulse width threshold.

16. The method of claim 15 , wherein the fixed pacing pulse width is approximately one millisecond, and the maximum pacing pulse width threshold is approximately one millisecond.

17. An implantable medical device comprising:

a memory; and

a processor configured for:

automatically determining one or more parameters of an exposure operating mode based on at least one of stored information related to sensed physiological events and/or stored information related to therapy provided over a predetermined period time by:

analyzing at least one of a maximum pacing amplitude and/or a maximum pacing pulse width measured during the predetermined period of time, wherein the stored information includes the maximum pacing amplitude and/or maximum pacing pulse width measured during the predetermined period of time; and

selecting at least one of a pacing amplitude and/or a pacing pulse width to be delivered during the exposure operating mode based on the analysis;

after automatically determining the one or more parameters of the exposure operating mode, storing the automatically determined parameters of the exposure operating mode in the memory;

switching operation of the implantable medical device from parameters of a current operating mode to the one or more automatically determined parameters of the exposure operating mode; and

delivering therapy by implementing the one or more automatically determined parameters of the exposure operating mode.

18. The device of claim 17 , wherein the processor is further configured for:

selecting the pacing amplitude to be delivered during the exposure operating mode as a fixed pacing amplitude when the maximum pacing amplitude measured during the predetermined period of time is less than a maximum pacing amplitude threshold; and

selecting the pacing amplitude to be delivered during the exposure operating mode as the maximum pacing amplitude measured during the predetermined period of time when maximum pacing amplitude measured during the predetermined period of time is approximately equal to or greater than the maximum pacing amplitude threshold measured during the predetermined period of time,

wherein the fixed pacing amplitude is approximately five volts, and the maximum pacing amplitude threshold is approximately five volts.

19. The device of claim 17 , wherein the processor is further configured for:

selecting the pacing pulse width to be delivered during the exposure operating mode as a fixed pacing pulse width when the maximum pacing pulse width measured during the predetermined period of time is less than a maximum pacing pulse width threshold; and

selecting the pacing pulse width to be delivered during the exposure operating mode as maximum pulse width measured during the predetermined period of time when maximum pacing pulse width is approximately equal to or greater than the maximum pacing pulse width threshold,

wherein the fixed pacing pulse width is approximately one millisecond, and the maximum pacing pulse width threshold is approximately one millisecond.

20. The device of claim 17 , wherein the processor is further configured for:

analyzing an average PAV interval measured during the predetermined period of time, the stored information includes the average PAV interval measured during the predetermined period of time;

selecting a PAV interval to be implemented during the exposure operating mode as a first fixed PAV interval when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a first PAV interval threshold;

selecting the PAV interval to be implemented during the exposure operating mode as the average PAV interval measured during the predetermined period of time when the average PAV interval measured during the predetermined period of time is approximately equal to or greater than a second PAV interval threshold, and less than the first PAV interval threshold; and

selecting the PAV interval to be implemented during the exposure operating mode as a second fixed PAV interval when the average PAV interval measured during the predetermined period of time is less than the second PAV interval threshold,

wherein the first fixed PAV interval is approximately one hundred and ten milliseconds, the first PAV interval threshold is approximately one hundred and ten milliseconds, the second fixed PAV interval is approximately fifty milliseconds, and the second PAV interval threshold is approximately fifty milliseconds.

Assignments (1)

Continuity (4)

References Cited (87)