IP Library › Granted Patent US 12,279,850
Granted Patent B2
US 12,279,850 · App. 18/426,601 · Granted Apr 22, 2025

Methods for remote visual identification of heart conditions

Inventors: Baruch Schler (Petach Tikwa, IL); Jonathan Schler (Petach Tikwa, IL)
A61B5/0022A61B5/4082A61B5/4088G06N3/044G06N3/08G06V10/764G06V10/82G06V40/171G16H30/40G16H40/67G16H50/20G16H50/30G06V10/32
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Quick Facts
Patent No.
US 12,279,850
App. No.
18/426,601
Granted
Apr 22, 2025
Kind
B2
Abstract

A method and system for remotely detecting a heart-related condition is presented. The method includes receiving a facial image of a patient, wherein the facial image is retrieved from a data store and captured from the patient; extracting at least one facial feature from the facial image of the patient, wherein the at least one facial feature is represented as numerical descriptors of facial attributes, wherein the numerical descriptors include surface features of the at least one facial feature; and classifying the extracted at least one facial feature using a classifier, wherein the classifier maps the extracted at least one facial feature to at least one score indicative of a stage of the heart-related condition.

Claims (46)

1. A method for remotely detecting a heart-related condition, comprising:

receiving a facial image of a patient, wherein the facial image is retrieved from a data store and captured from the patient;

extracting at least one facial feature from the facial image of the patient, wherein the at least one facial feature is represented as numerical descriptors of facial attributes, wherein the numerical descriptors include surface features of the at least one facial feature;

classifying the extracted at least one facial feature using a classifier, wherein the classifier maps the extracted at least one facial feature to at least one score indicative of a stage of the heart-related condition; and

determining, using the classifier, a positive diagnosis and the stage of the heart-related condition for the facial image of the patient based on a plurality of scores from the classification, wherein the stage is one of a plurality of stages within a progression of the heart-related condition.

2. The method of claim 1 , further comprising:

pre-processing the facial image to standardize the facial image and detect a face within the facial image.

3. The method of claim 1 , further comprising:

comparing the at least one facial feature to sample facial features, wherein the sample facial features include data labels associated with respective sample facial features; and

selecting at least one matching sample facial feature that compares substantially closely to the at least one facial feature.

4. The method of claim 1 , wherein the classifier determines a confidence rating for each of the at least one score.

5. The method of claim 1 , wherein the numerical descriptors further include at least one of: geometric features, 3-dimensional profile, thermal profile, and color profiles.

6. The method of claim 1 , wherein the heart-related condition is any one of:

atherosclerosis, hypertension, coronary heart disease, cardiomyopathy, congestive heart failure, stroke, and chronic kidney disease.

7. The method of claim 1 , further comprising:

generating the classifier, wherein the classifier is generated for a unique type of heart-related condition.

8. The method of claim 7 , wherein generating the classifier further comprises:

receiving a labeled dataset including a set of facial images, wherein each facial image has at least one label indicating a presence of at least the heart-related condition;

extracting at least one facial feature from each of the facial images, wherein extracting further comprises converting the at least one facial feature as numerical descriptors of facial attributes; and

feeding the extracted at least one facial feature into a neural network to produce a trained machine learning model, wherein the classifier is ready when the trained machine learning models include enough facial features processed by the neural network.

9. A non-transitory computer readable medium having stored thereon instructions for a processing circuitry to execute the process, the process comprising:

receiving a facial image of a patient, wherein the facial image is retrieved from a data store and captured from the patient;

extracting at least one facial feature from the facial image of the patient, wherein the at least one facial feature is represented as numerical descriptors of facial attributes, wherein the numerical descriptors include surface features of the at least one facial feature;

classifying the extracted at least one facial feature using a classifier, wherein the classifier maps the extracted at least one facial feature to at least one score indicative of a stage of a heart-related condition; and

determining, using the classifier, a positive diagnosis and the stage of the heart-related condition for the facial image of the patient based on a plurality of scores from the classification, wherein the stage is one of a plurality of stages within a progression of the heart-related condition.

10. A system for remotely detecting a heart-related condition, comprising:

a processing circuitry; and

a memory, the memory containing instructions that, when executed by the processing circuitry, configure the system to:

receive a facial image of a patient, wherein the facial image is retrieved from a data store and captured from the patient;

extract at least one facial feature from the facial image of the patient, wherein the at least one facial feature is represented as numerical descriptors of facial attributes, wherein the numerical descriptors include surface features of the at least one facial feature; and

classify the extracted at least one facial feature using a classifier, wherein the classifier maps the extracted at least one facial feature to at least one score indicative of a stage of the heart-related condition; and

determine, using the classifier, a positive diagnosis and the stage of the heart-related condition for the facial image of the patient based on a plurality of scores from the classification, wherein the stage is one of a plurality of stages within a progression of the heart-related condition.

11. The system of claim 10 , wherein the system is configured to:

pre-process the facial image to standardize the facial image and detect a face within the facial image.

12. The system of claim 10 , wherein the system is configured to:

compare the at least one facial feature to sample facial features, wherein the sample facial features include data labels associated with respective sample facial features; and

selecting at least one matching sample facial feature that compares substantially closely to the at least one facial feature.

13. The system of claim 10 , wherein the classifier determines a confidence rating for each of the at least one score.

14. The system of claim 10 , wherein the numerical descriptors further include at least one of: geometric features, 3-dimensional profile, thermal profile, and color profiles.

15. The system of claim 10 , wherein the heart-related condition is any one of: atherosclerosis, hypertension, coronary heart disease, cardiomyopathy, congestive heart failure, stroke, and chronic kidney disease.

16. The system of claim 10 , wherein the system is configured to:

generate the classifier, wherein the classifier is generated for a unique type of heart-related condition.

17. The system of claim 16 , wherein the system is configured to:

receive a labeled dataset including a set of facial images, wherein each facial image has at least one label indicating a presence of at least the heart-related condition;

extract at least one facial feature from each of the facial images, wherein extracting further comprises converting the at least one facial feature as numerical descriptors of facial attributes; and

feed the extracted at least one facial feature into a neural network to produce a trained machine learning model, wherein the classifier is ready when the trained machine learning models include enough facial features processed by the neural network.

Continuity (4)
Continuation In Part 18045700 · Oct 11, 2022
Continuation In Part 17649452 · Jan 31, 2022
Division 16880683 · May 21, 2020
Related Publication 20240164640A1 · May 23, 2024
References Cited (33)
US 9839699B2 · Koronyo et al. · 2017 [cited by applicant]
US 11276498B2 · Schler et al. · 2022 [cited by applicant]
US 11308618B2 · Connor · 2022 [cited by examiner]
US 11908241B2 · Kononenko · 2024 [cited by examiner]
US 20080242950A1 · Jung et al. · 2008 [cited by applicant]
US 20140172310A1 · Chin et al. · 2014 [cited by applicant]
US 20170251985A1 · Howard · 2017 [cited by applicant]
US 20170258390A1 · Howard · 2017 [cited by applicant]
US 20180289334A1 · Brouwer et al. · 2018 [cited by applicant]
US 20180325441A1 · Deluca et al. · 2018 [cited by applicant]
US 20190110754A1 · Rao et al. · 2019 [cited by applicant]
US 20200221956A1 · Tzvieli et al. · 2020 [cited by applicant]
CN 110674773A · 2020 [cited by applicant]
CN 111816308 · 2020 [cited by examiner]
CN 113284613 · 2021 [cited by examiner]
KR 20170001106A · 2017 [cited by applicant]
KR 20200005986A · 2020 [cited by applicant]
WO 2021214346A1 · 2021 [cited by applicant]
“Eyes Reveal Early Alzheimer's Disease,” by Northwestern University, 2019, pp. 1-2, Science Daily. [cited by applicant]
Abuzaghleh, et al., “Skincure: an Innovative Smart Phone-Based Application to Assist in Melanoma Early Detection and Prevention,” Connecticut, 2015, https://arxiv.org/ftp/arxiv/papers/1501/1501.01075.pdf. [cited by applicant]
Cerquera-Jaramillo et al., “Visual Features in Alzheimer's Disease: From Basic Mechanisms to Clinical Overview,” 2018, Columbia, Hindawi, Neural Plasticity, vol. 2018, pp. 1-21. [cited by applicant]
Chupin, et al., “Fully Automatic Hippocampus Segmentation and Classification in Alzheimer's Disease and Mild Cognitive Impairment Applied on Data from ADNI,” pp. 579-587, 2009, https://www.ncbi.nlm.nih.gov/pmc/articles/… [cited by applicant]
Friston, et al., “A Multivariate Analysis of PET Activation Studies,” 1996, Human Brain Mapping, Open Access Research, vol. 4, Issue 2, pp. 140-151. [cited by applicant]
International Preliminary Report on Patentability for PCT Application No. PCT/IB2021/054394 dated Nov. 17, 2022. The International Bureau of WIPO. [cited by applicant]
International Search Report and Written Opinion of International Searching Authority for PCT/IB2021/054394, ISA/IL, Jerusalem, Israel. Dated: Aug. 17, 2021. [cited by applicant]
Investigacion, et al., “Detecting Eye Diseases Using a Smartphone,” 2015, Science Daily, pp. 1-2. [cited by applicant]
Lim, et al., “The Eye As a Biomarker for Alzheimer's Disease,” Frontiers in Neuroscience, Australia, 2016, pp. 1-14. [cited by applicant]
Martinez-Murcia et al., “Functional Activity Maps Based on Significance Measures and Independent Component Analysis,” 2013, Published in final edited form as: Comput Methods Programs Biomed. Jul. 2013; 111(1): 255-268. … [cited by applicant]
Murcia-Martinez et al., “A Spherical Brain Mapping of MR Images for the Detection of Alzheimer's Disease,” Current Alzheimer Research, vol. 13, Issue 5, 2016, pp. 575-588. [cited by applicant]
Padma, et al., “Segmentation and Classification of Brain CT Images Using Combined Wavelet Statistical Texture Features,” Arab J Sci Eng 39, 767-776 (2014). https://doi.org/10.1007/s13369-013-0649-3. [cited by applicant]
Zhang, et al., “3D Texture Analysis on MRI images of Alzheimer's Disease,” Brain Imaging and Behavior 6, 61-69 (2012). https://doi.org/10.1007/s11682-011-9142-3. [cited by applicant]
Zhang, et al., “Classification of Alzheimer Disease Based on Structural Magnetic Resonance Imaging by Kernel Support Vector Machine Decision Tree,” Progress in Electromagnetics Research, vol. 144, pp. 171-184, 2014, Chi… [cited by applicant]
Zhang, et al., “Detection of Subjects and Brain Regions Related to Alzheimer's Disease Using 3D MRI Scans Based on Eigenbrain and Machine Learning,” 2015, China, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451357/. [cited by applicant]