IP Library › Granted Patent US 12,285,616
Granted Patent B2
US 12,285,616 · App. 17/863,735 · Granted Apr 29, 2025

Systems, devices, and methods for electromechanical sensing and mapping

Inventor: N. Parker Willis (Atherton, CA)
Assignee: EBR SYSTEMS, INC.
A61N1/36578A61N1/025A61N1/37217A61B5/1102A61B5/1126A61B5/35A61B5/7278
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Quick Facts
Patent No.
US 12,285,616
App. No.
17/863,735
Granted
Apr 29, 2025
Kind
B2
Abstract

Systems, devices, and methods for tracking and determining the motion of a cardiac implant is disclosed. The motion of the implant is determined by transmitting acoustic energy to a tissue location using an acoustic controller-transmitter comprising an array of acoustic transducers; wherein the implant is configured to convert the transmitted acoustic energy to electrical energy; and the tracking is achieved by determining the electrical energy delivered to the tissue throughout one or more cardiac cycles in order to create a motion profile of the cardiac implant.

Claims (76)

1. A method for tracking and/or determining cardiac motion, comprising:

tracking a location of an acoustic receiver-converter throughout a cardiac cycle relative to cardiac tissue;

creating a motion profile of the receiver-converter based on the tracked location;

using the motion profile in one or more of the following steps—

(a) normalizing the motion profile with electrocardiogram (EKG) data,

(b) mapping a cardiac motion of the cardiac tissue based on the motion profile, and/or

(c) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the motion profile and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction; and

delivering, via the receiver-converter electrical energy to the cardiac tissue based at least in part on (a), (b), and/or (c).

2. The method of claim 1 , further comprising determining a position of the receiver-converter at the end of diastole of the cardiac tissue.

3. The method of claim 2 wherein the electrical energy comprises pacing stimulation, and further comprising delivering acoustic energy to the receiver-converter sufficient to trigger the pacing stimulation of the cardiac tissue based on the determination that the receiver-converter is at the position at the end of diastole.

4. The method of claim 1 wherein tracking the location of the receiver-converter comprises detecting the electrical energy delivered by the receiver-converter to the cardiac tissue.

5. The method of claim 1 wherein the method comprises normalizing the motion profile with the EKG data.

6. The method of claim 1 wherein the method comprises mapping the cardiac motion of the cardiac tissue based on the motion profile.

7. The method of claim 1 wherein the method comprises determining the magnitude of the motion of the receiver-converter through the cardiac cycle based on the motion profile and correlating the magnitude of the motion of the receiver-converter to the changes in ejection fraction.

8. A method for tracking and/or determining cardiac motion, comprising:

detecting electrical energy delivered by an acoustic receiver-converter to cardiac tissue throughout a cardiac cycle to dynamically track three-dimensional (3D) motion data of the receiver-converter; and

(a) normalizing the 3D motion data with electrocardiogram (EKG) data,

(b) mapping a location of the cardiac tissue based on the 3D motion data,

(c) mapping the location of the cardiac tissue electromechanically by combining the 3D motion data with electrogram (EGM) data, and/or

(d) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the 3D motion data and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction;

wherein the electrical energy delivered by the receiver-converter to the cardiac tissue is based at least in part on (a), (b), (c), and/or (d).

9. The method of claim 8 , further comprising determining a position of the receiver-converter at the end of diastole of the cardiac tissue.

10. The method of claim 8 , wherein the electrical energy comprises pacing stimulation, and further comprising delivering acoustic energy to the receiver-converter sufficient to trigger the pacing stimulation of the cardiac tissue based on the determination that the receiver-converter is at the position at the end of diastole.

11. The method of claim 8 wherein detecting the electrical energy comprises detecting the electrical energy delivered by the receiver-stimulator to the location of the cardiac tissue.

12. The method of claim 11 , further comprising:

mapping the location of the cardiac tissue electromechanically by combining the 3D motion data with the EGM data; and

collecting the EGM data at the location of the cardiac tissue.

13. The method of claim 12 wherein collecting the EGM data comprises collecting the EGM data with the receiver-converter.

14. The method of claim 8 wherein the method comprises normalizing the 3D motion data with the EKG data.

15. The method of claim 8 wherein the method comprises mapping the location of the cardiac tissue based on the 3D motion data.

16. The method of claim 8 wherein the method comprises mapping the location of the cardiac tissue electromechanically by combining the 3D motion data with the EGM data.

17. The method of claim 8 wherein the method comprises determining the magnitude of the motion of the receiver-converter through the cardiac cycle based on the 3D motion data and correlating the magnitude of the motion of the receiver-converter to the changes in ejection fraction.

18. A method for tracking and/or determining cardiac motion, comprising:

tracking a location of an acoustic receiver-converter throughout a cardiac cycle relative to cardiac tissue;

creating a motion profile of the receiver-converter based on the tracked location;

using the motion profile in one or more of the following steps—

(a) normalizing the motion profile with electrocardiogram (EKG) data,

(b) mapping a cardiac motion of the cardiac tissue based on the motion profile,

(c) correlating the motion profile with electrogram (EGM) data to create an electromechanical motion profile, and/or

(d) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the motion profile and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction; and

determining a position of the receiver-converter at the end of diastole of the cardiac tissue;

and

delivering acoustic energy to the receiver-converter sufficient to trigger pacing stimulation of the cardiac tissue based on the determination that the receiver-converter is at the position at the end of diastole.

19. The method of claim 18 wherein the method further comprises:

correlating the motion profile with the EGM data to create the electromechanical motion profile; and

collecting the EGM data with the receiver-converter at the location of the cardiac tissue.

20. The method of claim 18 wherein the method comprises correlating the motion profile with the EGM data to create the electromechanical motion profile.

21. A system for tracking and/or determining cardiac motion, comprising:

a processing element; and

a non-transitory computer-readable storage element storing instructions that, when executed by the processing element, cause a tissue stimulation system to perform operations comprising—

tracking a location of an acoustic receiver-converter throughout a cardiac cycle relative to cardiac tissue;

creating a motion profile of the receiver-converter based on the tracked location; and

using the motion profile in one or more of the following steps—

(a) normalizing the motion profile with electrocardiogram (EKG) data,

(b) mapping a cardiac motion of the cardiac tissue based on the motion profile, and/or

(c) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the motion profile and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction; and

delivering, via the receiver-converter, electrical energy to the cardiac tissue based at least in part on (a), (b), and/or (c).

22. A system for tracking and/or determining cardiac motion, comprising:

a processing element; and

a non-transitory computer-readable storage element storing instructions that, when executed by the processing element, cause a tissue stimulation system to perform operations comprising—

detecting electrical energy delivered by an acoustic receiver-converter to cardiac tissue throughout a cardiac cycle to dynamically track three-dimensional (3D) motion data of the receiver-converter; and

using the 3D motion data in one or more of the following steps—

(a) normalizing the 3D motion data with electrocardiogram (EKG) data,

(b) mapping a location of the cardiac tissue based on the 3D motion data,

(c) mapping the location of the cardiac tissue electromechanically by combining the 3D motion data with electrogram (EGM) data, and/or

(d) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the 3D motion data and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction;

wherein the electrical energy delivered by the receive-converter to the cardiac tissue is based at least in part on (a), (b), (c), and/or (d).

23. A method for tracking and/or determining cardiac motion, comprising:

tracking a location of an acoustic receiver-converter throughout a cardiac cycle relative to cardiac tissue by detecting electrical energy delivered by the receiver-converter to the cardiac tissue;

creating a motion profile of the receiver-converter based on the tracked location; and

using the motion profile in one or more of the following steps—

(a) normalizing the motion profile with electrocardiogram (EKG) data,

(b) mapping a cardiac motion of the cardiac tissue based on the motion profile,

(c) correlating the motion profile with electrogram (EGM) data to create an electromechanical motion profile, and/or

(d) determining a magnitude of a motion of the receiver-converter through the cardiac cycle based on the motion profile and correlating the magnitude of the motion of the receiver-converter to changes in ejection fraction;

wherein the electrical energy delivered by the receiver-converter to the cardiac tissue is based at least in part on (a), (b), (c), and/or (d).

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF INVENTOR N. PARKER WILLIS PREVIOUSLY RECORDED ON REEL 60494 FRAME 860. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 19, 2024
From: WILLIS, NATHANIEL PARKER
To: EBR SYSTEMS, INC.
Reel/Frame 069746/0279 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2022
From: WILLIS, N. PARKER
To: EBR SYSTEMS, INC.
Reel/Frame 060494/0860 →
Continuity (4)
Continuation 16637130
Provisional Application 62542741 · Aug 8, 2017
Related Publication 20220347482A1 · Nov 3, 2022
Related Publication 20240139523A9 · May 2, 2024
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