IP Library › Granted Patent US 12,295,832
Granted Patent B2
US 12,295,832 · App. 17/486,361 · Granted May 13, 2025

Prosthetic heart valve having improved commissure supports

Inventors: Ziv Yohanan (Kfar Hahoresh, IL); Tamir S. Levi (Zikhron Yaakov, IL); Netanel Benichou (D.n. Hof Hacarmel, IL); Michael Bukin (Pardes Hanna, IL); Nikolai Gurovich (Hadera, IL); Elena Sherman (Pardes Hana, IL)
Assignee: EDWARDS LIFESCIENCES CORPORATION
A61F2/2409A61F2/2412A61F2/2418A61F2/2433A61F2220/0075A61F2230/0013A61F2230/0054A61F2250/0036A61F2250/0039
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Quick Facts
Patent No.
US 12,295,832
App. No.
17/486,361
Granted
May 13, 2025
Kind
B2
Abstract

A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.

Claims (28)

1. A prosthetic heart valve comprising:

a radially-collapsible annular frame having an inflow end and an outflow end and defining an axial direction between the inflow and outflow ends, the frame comprising three circumferentially spaced apart commissure attachment portions, wherein each commissure attachment portion comprises a first outer strut, a second outer strut, and an inner strut between the first and second outer struts, wherein the first outer strut, the second outer strut, and the inner strut extend in the axial direction; and

a valve structure positioned within the frame comprising three leaflets, with each leaflet having two opposing leaflet tabs, wherein adjacent pairs of the leaflet tabs join to form three commissures of the valve structure, and the three commissures are secured to the three commissure attachment portions of the frame such that the valve structure is configured to open during systole and close during diastole when the prosthetic heart valve is implanted in a patient,

wherein at each commissure, a first leaflet tab of one of the leaflets and a second leaflet tab of another one of the leaflets are both secured to one of the commissure attachment portions of the frame via the first outer strut, the second outer strut, and the inner strut, and

wherein at each commissure, the first leaflet tab extends radially between the first outer strut and the inner strut, and the second leaflet tab extends radially between the second outer strut and the inner strut.

2. The prosthetic heart valve of claim 1 , wherein at each commissure the first outer strut, the second outer strut, and the inner strut are parallel to each other.

3. The prosthetic heart valve of claim 1 , wherein at each commissure the first outer strut, the second outer strut, and the inner strut all extend axially from a common base portion of the commissure attachment portion.

4. The prosthetic heart valve of claim 1 , wherein at each commissure the first leaflet tab is secured to the first outer strut and the second leaflet tab is secured to the second outer strut.

5. The prosthetic heart valve of claim 1 , wherein at each commissure the first leaflet tab is secured to the inner strut.

6. The prosthetic heart valve of claim 1 , wherein at each commissure the first leaflet tab and the second leaflet tab extend radially outwardly through the commissure attachment portion between the first and second outer struts.

7. The prosthetic heart valve of claim 1 , wherein at each commissure the first and second leaflet tabs extend circumferentially apart from each other at a location radially outside of the commissure attachment portion.

8. The prosthetic heart valve of claim 1 , wherein at each commissure the first and second leaflet tabs extend radially outwardly through the commissure attachment portion and then are folded back radially inwardly through the frame.

9. The prosthetic heart valve of claim 1 , wherein the frame comprises two apices at the outflow end between each two of the commissure attachment portions.

10. The prosthetic heart valve of claim 1 , further comprising an annular outer skirt positioned around the frame adjacent the inflow end of the frame.

11. The prosthetic heart valve of claim 1 , further comprising an annular inner skirt positioned inside the frame adjacent the inflow end of the frame.

12. A prosthetic heart valve comprising:

a radially-collapsible annular frame having an inflow end and an outflow end and defining an axial direction between the inflow and outflow ends, the frame comprising three circumferentially spaced apart commissure attachment portions, wherein each commissure attachment portion comprises a common base portion, a first outer strut, a second outer strut, and an inner strut between the first and second outer struts, and wherein the first outer strut, the second outer strut, and the inner strut all extend in parallel toward the outflow end from the common base portion; and

a valve structure positioned within the frame comprising three leaflets, with each leaflet having two opposing leaflet tabs, wherein adjacent pairs of the leaflet tabs join to form three commissures of the valve structure, and the three commissures are secured to the three commissure attachment portions of the frame such that the valve structure is configured to open during systole and close during diastole when the prosthetic heart valve is implanted in a patient.

13. The prosthetic heart valve of claim 1 , wherein at each commissure the first leaflet tab and the second leaflet tab extend radially outwardly through the commissure attachment portion between the first and second outer struts.

14. The prosthetic heart valve of claim 13 , wherein at each commissure the first and second leaflet tabs extend circumferentially apart from each other at a location radially outside of the commissure attachment portion.

15. The prosthetic heart valve of claim 14 , wherein at each commissure the first and second leaflet tabs extend radially outwardly through the commissure attachment portion and then are folded back radially inwardly through the frame.

16. A frame for a prosthetic heart valve, comprising:

a radially-collapsible and radially expandable annular network of struts,

wherein the frame has an inflow end and an outflow end and defining an axial direction between the inflow and outflow ends, and

wherein the network of struts comprises three circumferentially spaced apart commissure attachment portions configured to be secured to commissures of a valve structure, wherein each commissure attachment portion comprises a common base portion, a first outer strut, a second outer strut, and an inner strut between the first and second outer struts, and wherein the first outer strut, the second outer strut, and the inner strut all extend in parallel toward the outflow end from the common base portion.

17. The frame of claim 16 , wherein the network of struts further comprises two apices at the outflow end between each two of the commissure attachment portions.

18. The frame of claim 16 , wherein for each of the commissure attachment portions, the common base portion, the first outer strut, the second outer strut, and the inner strut together define boundaries of two separated commissure windows configured to receive portions of the valve structure extending therethrough.

19. The frame of claim 16 , wherein for each of the commissure attachment portions, the network of struts further comprises two additional struts extending from the common base portion toward the inflow end.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 30, 2023
From: YOHANAN, ZIV; LEVI, TAMIR S.; BENICHOU, NETANEL; BUKIN, MICHAEL; GUROVICH, NIKOLAI; SHERMAN, ELENA
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 063800/0774 →
Continuity (7)
Continuation 17088919 · Nov 4, 2020
Continuation 16525439 · Jul 29, 2019
Continuation 15697740 · Sep 7, 2017
Continuation 14922057 · Oct 23, 2015
Continuation 13708598 · Dec 7, 2012
Provisional Application 61569022 · Dec 9, 2011
Related Publication 20220008196A1 · Jan 13, 2022
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