IP Library Granted Patent US 12,303,301
Granted Patent B2
US 12,303,301 · App. 17/878,705 · Granted May 20, 2025

Intraoperative neural monitoring system and method

Inventors: Christopher Wybo (Brighton, MI); Darren Scarfe (LaSalle, CA); Aashish Shah (Ann Arbor, MI); Jacob A. Marks (Mansfield, MA); James G. Lee (South Weymouth, MA)
Assignee: DePuy Synthes Products, Inc.
A61B5/743A61B5/1104A61B5/1107A61B5/4893G06T11/206A61B2562/0219
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Quick Facts
Patent No.
US 12,303,301
App. No.
17/878,705
Granted
May 20, 2025
Kind
B2
Abstract

A neuromuscular sensing method includes transmitting an electrical stimulus from a distal end portion of an elongate stimulator extending within an intracorporeal treatment area of a subject and detecting an artificially induced response of at least two muscles of the subject in response to the transmitted electrical stimulus, each response being detected by a respective sensor in mechanical communication with the muscle. A graphical user interface (GUI) is transitioned from a first state to a second state; the first state indicating to the transmission of a stimulus with no artificially induced response detected, and the second state indicating the detection of the artificially induced response of the at least two muscles, and further identifying one of the at least two muscles as a primary muscle response.

Claims (45)

1. A method comprising:

applying a plurality of mechanical sensors to a patient to detect muscle movement;

detecting, using at least one of the plurality of mechanical sensors, an artificially induced response of a muscle of the patient; and

displaying, on a display having a graphical user interface (GUI):

if the response is a result of an electrical stimulus, at least one of:

an amplitude of the response; or

an identity of a nerve associated with the muscle; or

if the response is a spontaneous response:

a warning.

2. The method of claim 1 , further comprising determining that two muscles have responded to the electrical stimulus and displaying an indication of a primary response and an ancillary response.

3. The method of claim 2 , further comprising displaying a relative difference in magnitude between an amplitude of the primary response and an amplitude of the ancillary response.

4. The method of claim 2 , further comprising displaying an indication on the GUI for the primary response that has visually more weight than an indication for the ancillary response.

5. The method of claim 1 , further comprising displaying an indicator indicating a status.

6. The method of claim 5 , wherein the status is standby, stimulating, spontaneous, or nerve identified.

7. The method of claim 5 , wherein the indicator is a textual status indicator.

8. The method of claim 5 , wherein the indicator is a non-textual status indicator.

9. The method of claim 8 , wherein the indicator is a color.

10. An intraoperative neural monitoring system comprising:

a plurality of mechanical sensors to detect muscle movement; and

a processor configured to:

detect, using at least one of the plurality of mechanical sensors, an artificially induced response of a muscle of the patient; and

display, on a display having a graphical user interface (GUI):

if the response is a result of an electrical stimulus, at least one of:

an amplitude of the response; or

an identity of a nerve associated with the muscle; or

if the response is a spontaneous response:

a warning.

11. The system of claim 10 , wherein the processor is further configured to determine that two muscles have responded to the electrical stimulus and display an indication of a primary response and an ancillary response.

12. The system of claim 11 , wherein the processor is further configured to display a relative difference in magnitude between an amplitude of the primary response and an amplitude of the ancillary response.

13. The system of claim 11 , wherein the processor is further configured to display an indication on the GUI for the primary response that has visually more weight than an indication for the ancillary response.

14. The system of claim 10 , wherein the processor is further configured to display an indicator indicating a status.

15. The system of claim 14 , wherein the status is standby, stimulating, spontaneous, or nerve identified.

16. The system of claim 14 , wherein the indicator is a textual status indicator.

17. The system of claim 14 , wherein the indicator is a non-textual status indicator.

18. The system of claim 17 , wherein the indicator is a color.

19. A method comprising:

applying a plurality of mechanical sensors to a patient to detect muscle movement;

detecting, using at least one of the plurality of mechanical sensors, an artificially induced response of at least two muscles of the patient; and

displaying, on a display having a graphical user interface (GUI):

at least one of:

an amplitude of the response; or

an identity of a nerve associated with each muscle; and

an indication of a primary response; and

an indication of an ancillary response, wherein the indication for the primary response has visually more weight than an indication for the ancillary response.

20. The method of claim 19 , further comprising displaying a relative difference in magnitude between an amplitude of the primary response and an amplitude of the ancillary response.

Continuity (2)
Continuation 16586121 · Sep 27, 2019
Related Publication 20220370020A1 · Nov 24, 2022
References Cited (385)
US 3200814A · Taylor et al. · 1965 [cited by applicant]
US 3565080A · Walter et al. · 1971 [cited by applicant]
US 3797010A · Adler et al. · 1974 [cited by applicant]
US 4155353A · Rea et al. · 1979 [cited by applicant]
US 4493327A · Bergelson et al. · 1985 [cited by applicant]
US 4807642A · Brown · 1989 [cited by applicant]
US 4817628A · Zealear et al. · 1989 [cited by applicant]
US 4940453A · Cadwell · 1990 [cited by applicant]
US 4994015A · Cadwell · 1991 [cited by applicant]
US 5047005A · Cadwell · 1991 [cited by applicant]
US 5078674A · Cadwell · 1992 [cited by applicant]
US 5116304A · Cadwell · 1992 [cited by applicant]
US 5178145A · Rea · 1993 [cited by applicant]
US 5284153A · Raymond et al. · 1994 [cited by applicant]
US 5284154A · Raymond et al. · 1994 [cited by applicant]
US 5482038A · Ruff · 1996 [cited by applicant]
US 5566678A · Cadwell · 1996 [cited by applicant]
US 5593429A · Ruff · 1997 [cited by applicant]
US 5631667A · Cadwell · 1997 [cited by applicant]
US 5775331A · Raymond et al. · 1998 [cited by applicant]
US 5860939A · Wofford et al. · 1999 [cited by applicant]
US 5888370A · Becker et al. · 1999 [cited by applicant]
US 5993630A · Becker et al. · 1999 [cited by applicant]
US 5993632A · Becker et al. · 1999 [cited by applicant]
US 6030401A · Marino · 2000 [cited by applicant]
US 6093205A · McLeod et al. · 2000 [cited by applicant]
US 6181961B1 · Prass · 2001 [cited by applicant]
US 6183518B1 · Ross et al. · 2001 [cited by applicant]
US 6206921B1 · Guagliano et al. · 2001 [cited by applicant]
US 6221082B1 · Marino et al. · 2001 [cited by applicant]
US 6224603B1 · Marino · 2001 [cited by applicant]
US 6251140B1 · Marino et al. · 2001 [cited by applicant]
US 6264659B1 · Ross et al. · 2001 [cited by applicant]
US 6266394B1 · Marino · 2001 [cited by applicant]
US 6266558B1 · Gozani et al. · 2001 [cited by applicant]
US 6280447B1 · Marino et al. · 2001 [cited by applicant]
US 6287832B1 · Becker et al. · 2001 [cited by applicant]
US 6290724B1 · Marino · 2001 [cited by applicant]
US D450059S · Itou · 2001 [cited by applicant]
US 6312443B1 · Stone · 2001 [cited by applicant]
US 6324432B1 · Rigaux et al. · 2001 [cited by applicant]
US 6361508B1 · Johnson et al. · 2002 [cited by applicant]
US 6368325B1 · McKinley et al. · 2002 [cited by applicant]
US 6387070B1 · Marino et al. · 2002 [cited by applicant]
US 6387130B1 · Stone et al. · 2002 [cited by applicant]
US 6436143B1 · Ross et al. · 2002 [cited by applicant]
US 6466817B1 · Kaula et al. · 2002 [cited by applicant]
US 6478805B1 · Marino et al. · 2002 [cited by applicant]
US 6485518B1 · Cornwall et al. · 2002 [cited by applicant]
US 6491626B1 · Stone et al. · 2002 [cited by applicant]
US 6500128B2 · Marino · 2002 [cited by applicant]
US 6519319B1 · Marino et al. · 2003 [cited by applicant]
US 6530930B1 · Marino et al. · 2003 [cited by applicant]
US 6533797B1 · Stone et al. · 2003 [cited by applicant]
US 6540747B1 · Marino · 2003 [cited by applicant]
US 6564078B1 · Marino et al. · 2003 [cited by applicant]
US 6638281B2 · Gorek · 2003 [cited by applicant]
US 6641708B1 · Becker et al. · 2003 [cited by applicant]
US 6654634B1 · Prass · 2003 [cited by applicant]
US 6739112B1 · Marino · 2004 [cited by applicant]
US 6760616B2 · Hoey et al. · 2004 [cited by applicant]
US 6764452B1 · Gillespie et al. · 2004 [cited by applicant]
US 6764489B2 · Ferree · 2004 [cited by applicant]
US 6802844B2 · Ferree · 2004 [cited by applicant]
US 6805668B1 · Cadwell · 2004 [cited by applicant]
US 6807438B1 · Brun Del Re et al. · 2004 [cited by applicant]
US 6843790B2 · Ferree · 2005 [cited by applicant]
US 6852126B2 · Ahlgren · 2005 [cited by applicant]
US 6870109B1 · Villarreal · 2005 [cited by applicant]
US 6887248B2 · McKinley et al. · 2005 [cited by applicant]
US 6923814B1 · Hildebrand et al. · 2005 [cited by applicant]
US 6945973B2 · Bray · 2005 [cited by applicant]
US 6964674B1 · Matsuura et al. · 2005 [cited by applicant]
US 6972199B2 · Lebouitz et al. · 2005 [cited by applicant]
US 6981990B2 · Keller · 2006 [cited by applicant]
US 7001432B2 · Keller et al. · 2006 [cited by applicant]
US 7025769B1 · Ferree · 2006 [cited by applicant]
US 7050848B2 · Hoey et al. · 2006 [cited by applicant]
US 7072521B1 · Cadwell · 2006 [cited by applicant]
US 7079883B2 · Marino et al. · 2006 [cited by applicant]
US 7160303B2 · Keller · 2007 [cited by applicant]
US 7162850B2 · Marino et al. · 2007 [cited by applicant]
US 7166113B2 · Arambula et al. · 2007 [cited by applicant]
US 7175662B2 · Link et al. · 2007 [cited by applicant]
US 7177677B2 · Kaula et al. · 2007 [cited by applicant]
US 7207949B2 · Miles et al. · 2007 [cited by applicant]
US 7214197B2 · Prass · 2007 [cited by applicant]
US 7214225B2 · Ellis et al. · 2007 [cited by applicant]
US 7216001B2 · Rupp et al. · 2007 [cited by applicant]
US 7230688B1 · Villarreal · 2007 [cited by applicant]
US 7236832B2 · Hemmerling et al. · 2007 [cited by applicant]
US 7267691B2 · Keller et al. · 2007 [cited by applicant]
US 7296500B1 · Martinelli · 2007 [cited by applicant]
US 7320689B2 · Keller · 2008 [cited by applicant]
US 7338531B2 · Ellis et al. · 2008 [cited by applicant]
US 7341590B2 · Ferree · 2008 [cited by applicant]
US D565581S · Gunn et al. · 2008 [cited by applicant]
US D565584S · Gunn et al. · 2008 [cited by applicant]
US 7367958B2 · McBean et al. · 2008 [cited by applicant]
US 7374448B2 · Jepsen et al. · 2008 [cited by applicant]
US 7379767B2 · Rea · 2008 [cited by applicant]
US 7470236B1 · Kelleher et al. · 2008 [cited by applicant]
US 7485146B1 · Crook et al. · 2009 [cited by applicant]
US 7522953B2 · Kaula et al. · 2009 [cited by applicant]
US 7527629B2 · Link et al. · 2009 [cited by applicant]
US 7527649B1 · Blain · 2009 [cited by applicant]
US 7553307B2 · Bleich et al. · 2009 [cited by applicant]
US 7555343B2 · Bleich · 2009 [cited by applicant]
US 7569067B2 · Keller · 2009 [cited by applicant]
US 7578819B2 · Bleich et al. · 2009 [cited by applicant]
US 7582058B1 · Miles et al. · 2009 [cited by applicant]
US 7583991B2 · Rea · 2009 [cited by applicant]
US 7611522B2 · Gorek · 2009 [cited by applicant]
US 7618423B1 · Valentine et al. · 2009 [cited by applicant]
US 7628813B2 · Link · 2009 [cited by applicant]
US 7634315B2 · Cholette · 2009 [cited by applicant]
US 7657308B2 · Miles et al. · 2010 [cited by applicant]
US 7664544B2 · Miles et al. · 2010 [cited by applicant]
US 7666195B2 · Kelleher et al. · 2010 [cited by applicant]
US 7668588B2 · Kovacs · 2010 [cited by applicant]
US 7691057B2 · Miles et al. · 2010 [cited by applicant]
US 7693562B2 · Marino et al. · 2010 [cited by applicant]
US 7708776B1 · Blain et al. · 2010 [cited by applicant]
US 7713463B1 · Reah et al. · 2010 [cited by applicant]
US 7722613B2 · Sutterlin et al. · 2010 [cited by applicant]
US 7722673B2 · Keller · 2010 [cited by applicant]
US 7738968B2 · Bleich · 2010 [cited by applicant]
US 7738969B2 · Bleich · 2010 [cited by applicant]
US 7740631B2 · Bleich et al. · 2010 [cited by applicant]
US 7766816B2 · Chin et al. · 2010 [cited by applicant]
US 7776049B1 · Curran et al. · 2010 [cited by applicant]
US 7776094B2 · McKinley et al. · 2010 [cited by applicant]
US 7785248B2 · Annest et al. · 2010 [cited by applicant]
US 7785253B1 · Arambula et al. · 2010 [cited by applicant]
US D623193S · Cameron et al. · 2010 [cited by applicant]
US 7815682B1 · Peterson et al. · 2010 [cited by applicant]
US 7819801B2 · Miles et al. · 2010 [cited by applicant]
US 7828855B2 · Ellis et al. · 2010 [cited by applicant]
US 7833251B1 · Ahlgren et al. · 2010 [cited by applicant]
US 7857813B2 · Schmitz et al. · 2010 [cited by applicant]
US 7862592B2 · Peterson et al. · 2011 [cited by applicant]
US 7862614B2 · Keller et al. · 2011 [cited by applicant]
US 7867277B1 · Tohmeh · 2011 [cited by applicant]
US D632698S · Judy et al. · 2011 [cited by applicant]
US 7883527B2 · Matsuura et al. · 2011 [cited by applicant]
US 7887538B2 · Bleich et al. · 2011 [cited by applicant]
US 7887568B2 · Ahlgren · 2011 [cited by applicant]
US 7887595B1 · Pimenta · 2011 [cited by applicant]
US 7892173B2 · Miles et al. · 2011 [cited by applicant]
US 7901430B2 · Matsuura et al. · 2011 [cited by applicant]
US 7905840B2 · Pimenta et al. · 2011 [cited by applicant]
US 7905886B1 · Curran et al. · 2011 [cited by applicant]
US 7914350B1 · Bozich et al. · 2011 [cited by applicant]
US 7918849B2 · Bleich et al. · 2011 [cited by applicant]
US 7918891B1 · Curran et al. · 2011 [cited by applicant]
US 7920922B2 · Gharib et al. · 2011 [cited by applicant]
US 7927337B2 · Keller · 2011 [cited by applicant]
US 7935051B2 · Miles et al. · 2011 [cited by applicant]
US 7938830B2 · Saadat et al. · 2011 [cited by applicant]
US 7942104B2 · Butcher et al. · 2011 [cited by applicant]
US 7942826B1 · Scholl et al. · 2011 [cited by applicant]
US 7946236B2 · Butcher · 2011 [cited by applicant]
US 7959577B2 · Schmitz et al. · 2011 [cited by applicant]
US 7962191B2 · Marino et al. · 2011 [cited by applicant]
US 7963915B2 · Bleich · 2011 [cited by applicant]
US 7963927B2 · Kelleher et al. · 2011 [cited by applicant]
US 7981058B2 · Akay · 2011 [cited by applicant]
US 7981144B2 · Walsh et al. · 2011 [cited by applicant]
US 7991463B2 · Kelleher et al. · 2011 [cited by applicant]
US 8000782B2 · Gharib et al. · 2011 [cited by applicant]
US 8005535B2 · Gharib et al. · 2011 [cited by applicant]
US 8012212B2 · Link et al. · 2011 [cited by applicant]
US 8016767B2 · Miles et al. · 2011 [cited by applicant]
US 8016776B2 · Bourget et al. · 2011 [cited by applicant]
US 8027716B2 · Gharib et al. · 2011 [cited by applicant]
US 8048080B2 · Bleich et al. · 2011 [cited by applicant]
US 8050769B2 · Gharib et al. · 2011 [cited by applicant]
US 8055349B2 · Gharib et al. · 2011 [cited by applicant]
US 8062298B2 · Schmitz et al. · 2011 [cited by applicant]
US 8062300B2 · Schmitz et al. · 2011 [cited by applicant]
US 8062369B2 · Link · 2011 [cited by applicant]
US 8062370B2 · Keller et al. · 2011 [cited by applicant]
US 8063770B2 · Costantino · 2011 [cited by applicant]
US 8068912B2 · Kaula et al. · 2011 [cited by applicant]
US 8070812B2 · Keller · 2011 [cited by applicant]
US 8074591B2 · Butcher et al. · 2011 [cited by applicant]
US 8075499B2 · Nathan et al. · 2011 [cited by applicant]
US 8075601B2 · Young · 2011 [cited by applicant]
US 8083685B2 · Fagin et al. · 2011 [cited by applicant]
US 8083796B1 · Raiszadeh et al. · 2011 [cited by applicant]
US 8088163B1 · Kleiner · 2012 [cited by applicant]
US 8088164B2 · Keller · 2012 [cited by applicant]
US 8090436B2 · Hoey et al. · 2012 [cited by applicant]
US 8092455B2 · Neubardt et al. · 2012 [cited by applicant]
US 8092456B2 · Bleich et al. · 2012 [cited by applicant]
US 8103339B2 · Rea · 2012 [cited by applicant]
US 8114019B2 · Miles et al. · 2012 [cited by applicant]
US 8114162B1 · Bradley · 2012 [cited by applicant]
US 8123668B2 · Annest et al. · 2012 [cited by applicant]
US 8133173B2 · Miles et al. · 2012 [cited by applicant]
US 8137284B2 · Miles et al. · 2012 [cited by applicant]
US 8147421B2 · Farquhar et al. · 2012 [cited by applicant]
US 8147551B2 · Link et al. · 2012 [cited by applicant]
US 8165653B2 · Marino et al. · 2012 [cited by applicant]
US 8167915B2 · Ferree et al. · 2012 [cited by applicant]
US 8172750B2 · Miles et al. · 2012 [cited by applicant]
US 8206312B2 · Farquhar · 2012 [cited by applicant]
US 8255044B2 · Miles et al. · 2012 [cited by applicant]
US 8255045B2 · Gharib et al. · 2012 [cited by applicant]
US 8255830B2 · Ording et al. · 2012 [cited by applicant]
US 8303515B2 · Miles et al. · 2012 [cited by applicant]
US 8337410B2 · Kelleher et al. · 2012 [cited by applicant]
US 8343065B2 · Bartol et al. · 2013 [cited by applicant]
US 8343079B2 · Bartol et al. · 2013 [cited by applicant]
US 8394129B2 · Morgenstern et al. · 2013 [cited by applicant]
US D681046S · Davis · 2013 [cited by applicant]
US 8500653B2 · Farquhar · 2013 [cited by applicant]
US 8500738B2 · Wolf, II · 2013 [cited by applicant]
US 8517954B2 · Bartol et al. · 2013 [cited by applicant]
US 8535224B2 · Reaston et al. · 2013 [cited by applicant]
US 8538539B2 · Pothier et al. · 2013 [cited by applicant]
US 8556808B2 · Miles et al. · 2013 [cited by applicant]
US 8562539B2 · Marino · 2013 [cited by applicant]
US 8562660B2 · Peyman · 2013 [cited by applicant]
US 8568317B1 · Gharib et al. · 2013 [cited by applicant]
US 8591431B2 · Calancie et al. · 2013 [cited by applicant]
US 8641638B2 · Kelleher et al. · 2014 [cited by applicant]
US 8731654B2 · Johnson et al. · 2014 [cited by applicant]
US 8784330B1 · Scholl et al. · 2014 [cited by applicant]
US 8792977B2 · Kakei et al. · 2014 [cited by applicant]
US 8855822B2 · Bartol et al. · 2014 [cited by applicant]
US 8864654B2 · Kleiner et al. · 2014 [cited by applicant]
US 8936626B1 · Tohmeh et al. · 2015 [cited by applicant]
US 8945004B2 · Miles et al. · 2015 [cited by applicant]
US 8958869B2 · Kelleher et al. · 2015 [cited by applicant]
US 8982593B2 · Nondahl et al. · 2015 [cited by applicant]
US 8989855B2 · Murphy et al. · 2015 [cited by applicant]
US 8989866B2 · Gharib et al. · 2015 [cited by applicant]
US 9014776B2 · Marino et al. · 2015 [cited by applicant]
US 9014797B2 · Shiffman et al. · 2015 [cited by applicant]
US 9037250B2 · Kaula et al. · 2015 [cited by applicant]
US 9039630B2 · Bartol et al. · 2015 [cited by applicant]
US 9066701B1 · Finley et al. · 2015 [cited by applicant]
US 9084550B1 · Bartol · 2015 [cited by examiner]
US 9084551B2 · Brunnett et al. · 2015 [cited by applicant]
US 9131947B2 · Ferree · 2015 [cited by applicant]
US 9192415B1 · Arnold et al. · 2015 [cited by applicant]
US 9295396B2 · Gharib et al. · 2016 [cited by applicant]
US 9295401B2 · Cadwell · 2016 [cited by applicant]
US 9301711B2 · Bartol et al. · 2016 [cited by applicant]
US 9392953B1 · Gharib · 2016 [cited by applicant]
US 9446259B2 · Phillips et al. · 2016 [cited by applicant]
US D799505S · Park et al. · 2017 [cited by applicant]
US D820288S · Howell et al. · 2018 [cited by applicant]
US D853422S · Zimmerman et al. · 2019 [cited by applicant]
US 10383714B2 · Cinquin et al. · 2019 [cited by applicant]
US 10420480B1 · Schermerhorn · 2019 [cited by examiner]
US D918241S · Sheridan et al. · 2021 [cited by applicant]
US D921030S · Shah et al. · 2021 [cited by applicant]
US 11789598B2 · Han et al. · 2023 [cited by applicant]
US 20010031916A1 · Bennett et al. · 2001 [cited by applicant]
US 20020038092A1 · Stanaland et al. · 2002 [cited by applicant]
US 20020165590A1 · Crowe et al. · 2002 [cited by applicant]
US 20030074037A1 · Karas et al. · 2003 [cited by applicant]
US 20040077969A1 · Onda et al. · 2004 [cited by applicant]
US 20040082877A1 · Kouou et al. · 2004 [cited by applicant]
US 20040186535A1 · Knowlton · 2004 [cited by applicant]
US 20040230138A1 · Inoue et al. · 2004 [cited by applicant]
US 20040243018A1 · Organ et al. · 2004 [cited by applicant]
US 20050075578A1 · Gharib et al. · 2005 [cited by applicant]
US 20050085741A1 · Hoskonen et al. · 2005 [cited by applicant]
US 20050102007A1 · Ayal et al. · 2005 [cited by applicant]
US 20050240086A1 · Akay · 2005 [cited by applicant]
US 20050245839A1 · Stivoric et al. · 2005 [cited by applicant]
US 20050280531A1 · Fadem et al. · 2005 [cited by applicant]
US 20050283204A1 · Buhlmann et al. · 2005 [cited by applicant]
US 20060020177A1 · Seo et al. · 2006 [cited by applicant]
US 20060052726A1 · Weisz et al. · 2006 [cited by applicant]
US 20060135888A1 · Mimnagh-Kelleher et al. · 2006 [cited by applicant]
US 20060270949A1 · Mathie et al. · 2006 [cited by applicant]
US 20070038155A1 · Kelly et al. · 2007 [cited by applicant]
US 20070049826A1 · Willis · 2007 [cited by applicant]
US 20070232958A1 · Donofrio et al. · 2007 [cited by applicant]
US 20070265675A1 · Lund et al. · 2007 [cited by applicant]
US 20070276270A1 · Tran · 2007 [cited by applicant]
US 20080051643A1 · Park et al. · 2008 [cited by applicant]
US 20080058656A1 · Costello et al. · 2008 [cited by applicant]
US 20080167695A1 · Tehrani et al. · 2008 [cited by applicant]
US 20080234767A1 · Salmon et al. · 2008 [cited by applicant]
US 20080306363A1 · Chaiken et al. · 2008 [cited by applicant]
US 20080306397A1 · Bonmassar et al. · 2008 [cited by applicant]
US 20080312560A1 · Jamsen et al. · 2008 [cited by applicant]
US 20080312709A1 · Volpe et al. · 2008 [cited by applicant]
US 20090036747A1 · Hayter et al. · 2009 [cited by applicant]
US 20090062696A1 · Nathan et al. · 2009 [cited by applicant]
US 20090069709A1 · Schmitz et al. · 2009 [cited by applicant]
US 20090069722A1 · Flaction et al. · 2009 [cited by applicant]
US 20090076336A1 · Bly et al. · 2009 [cited by applicant]
US 20090105604A1 · Bertagnoli · 2009 [cited by examiner]
US 20090171381A1 · Schmitz et al. · 2009 [cited by applicant]
US 20090192413A1 · Sela et al. · 2009 [cited by applicant]
US 20090228068A1 · Buhlmann et al. · 2009 [cited by applicant]
US 20090247910A1 · Klapper · 2009 [cited by applicant]
US 20090306741A1 · Hogle et al. · 2009 [cited by applicant]
US 20090318779A1 · Tran · 2009 [cited by applicant]
US 20100137748A1 · Sone et al. · 2010 [cited by applicant]
US 20100152619A1 · Kalpaxis et al. · 2010 [cited by applicant]
US 20100152622A1 · Teulings · 2010 [cited by applicant]
US 20100152623A1 · Williams · 2010 [cited by applicant]
US 20100168559A1 · Tegg et al. · 2010 [cited by applicant]
US 20100262042A1 · Kirn · 2010 [cited by applicant]
US 20100292617A1 · Lei et al. · 2010 [cited by applicant]
US 20110004207A1 · Wallace et al. · 2011 [cited by applicant]
US 20110230782A1 · Bartol et al. · 2011 [cited by applicant]
US 20110237974A1 · Bartol et al. · 2011 [cited by applicant]
US 20110270121A1 · Johnson et al. · 2011 [cited by applicant]
US 20110301665A1 · Mercanzini et al. · 2011 [cited by applicant]
US 20120053491A1 · Nathan et al. · 2012 [cited by applicant]
US 20120191003A1 · Garabedian et al. · 2012 [cited by applicant]
US 20130197321A1 · Wilson · 2013 [cited by applicant]
US 20130204097A1 · Rondoni et al. · 2013 [cited by applicant]
US 20130213659A1 · Luyster et al. · 2013 [cited by applicant]
US 20130253533A1 · Bartol et al. · 2013 [cited by applicant]
US 20140020178A1 · Stashuk et al. · 2014 [cited by applicant]
US 20140066803A1 · Choi · 2014 [cited by applicant]
US 20140088029A1 · Sugimoto et al. · 2014 [cited by applicant]
US 20140121555A1 · Scott et al. · 2014 [cited by applicant]
US 20140148725A1 · Cadwell · 2014 [cited by applicant]
US 20140163411A1 · Rea · 2014 [cited by applicant]
US 20140275926A1 · Scott et al. · 2014 [cited by applicant]
US 20140276195A1 · Papay et al. · 2014 [cited by applicant]
US 20140358026A1 · Mashiach et al. · 2014 [cited by applicant]
US 20150032022A1 · Stone et al. · 2015 [cited by applicant]
US 20150040007A1 · Schubert et al. · 2015 [cited by applicant]
US 20150045783A1 · Edidin · 2015 [cited by applicant]
US 20150051506A1 · Wybo et al. · 2015 [cited by applicant]
US 20150112325A1 · Whitman · 2015 [cited by applicant]
US 20150230749A1 · Gharib et al. · 2015 [cited by applicant]
US 20150342521A1 · Narita et al. · 2015 [cited by applicant]
US 20150342621A1 · Jackson, III · 2015 [cited by applicant]
US 20160051812A1 · Montgomery, Jr. et al. · 2016 [cited by applicant]
US 20220370020A1 · Wybo et al. · 2022 [cited by applicant]
EP 1417000A2 · 2004 [cited by applicant]
EP 1575010A1 · 2005 [cited by applicant]
EP 2231003A1 · 2010 [cited by applicant]
EP 2535082A1 · 2012 [cited by applicant]
FR 2920087A1 · 2009 [cited by applicant]
WO 0078209A2 · 2000 [cited by applicant]
WO 2007024147A1 · 2007 [cited by applicant]
WO 2014160832A2 · 2014 [cited by applicant]
WO 2015171619A1 · 2015 [cited by applicant]
WO 2016100340A1 · 2016 [cited by applicant]
Bartol et al., “Arthroscopic Microscopic Discectomy in Awake Patients: The Effectiveness of Local/Neurolept Anaesthetic”, Canadian Spine Society Meeting, Vernon, BC, Canada, 2002. [cited by applicant]
Bartol, “Use of Nerve Stimulator to Localize the Spinal Nerve Root During Arthroscopic Discectomy Procedures”, Canadian Spine Society Meeting, Vernon, BC, Canada, Mar. 2002. [cited by applicant]
Beck et al., “Intraoperative Facial Nerve Monitoring Technical Aspects”, Official Journal of the American Academy of Otolaryngology—Head and Neck Surgery Foundation, Apr. 27, 1989. [cited by applicant]
Begg et al., “Computational Intelligence for Movement Sciences: Neural Networks and other Emerging Techniques”, 2006. [cited by applicant]
Boston et al., “Sensory Evoked Potentials: A System for Clinical Testing and Patient Monitoring”, International Journal of Clinical Monitoring and Computing, Mar. 1984, pp. 13-19. [cited by applicant]
Bourke et al., “A Threshold-Based Fall-Detection Algorithm Using a Bi-Axial Gyroscope Sensor”, Medical Engineering & Physics, vol. 30, No. 1, 2008, pp. 84-90. [cited by applicant]
Dulguerov et al., “Postparotidectomy Facial Nerve Paralysis: Possible Etiologic Factors and Results with Routine Facial Nerve Monitoring”, The Laryngoscope, Lippincott Williams & Wilkins, Inc. Philadelphia, Pennsylvania… [cited by applicant]
Fee Jr. et al., “EMG Reaction in Muscles About the Knee to Passive Velocity, Acceleration, and Jerk Manipulations”, Journal of Electromyography and Kinesiology, vol. 19, No. 3, Jun. 1, 2009, pp. 467-475. [cited by applicant]
Friedman et al., “Somatosensory Evoked Potentials After Sequential Extremity Stimulation: A New Method for Improved Monitoring Accuracy”, Neurosurgery, vol. 21, No. 5, Nov. 1, 1987, pp. 755-758. [cited by applicant]
Gopalan, “Microprocessor-Based System for Monitoring Spinal Evoked Potentials During Surgery”, IEEE Transactions on Biomedical Engineering, vol. BME-22, No. 10, Oct. 1986, pp. 982-985. [cited by applicant]
Harper et al., “Facial Nerve Electromyography and other Cranial Nerve Monitoring”, Journal of Clinical Neurophysiology, vol. 15, No. 3, 1998, pp. 206-216. [cited by applicant]
Herdmann et al., “Spinal Cord and Nerve Root Monitoring in Spine Surgery and Related Procedures”, Spine, vol. 21, No. 7, 1996, pp. 879-885. [cited by applicant]
Holland, “Continuous Electromyographic Monitoring to Detect Nerve Root Injury During Thoracolumbar Scoliosis Surgery”, Spine, vol. 22, No. 21, 1997, pp. 2547-2550. [cited by applicant]
Imai, “Automated Spinal Cord Monitoring for Spinal Surgery”, Paraplegia, vol. 27, No. 3, 1989, pp. 204-211. [cited by applicant]
Koceja et al., “Methodology for the Quantitative Assessment of Human Crossed-Spinal Reflex Pathways”, Medical and Biological Engineering and Computing, vol. 29, No. 6, Nov. 1991, pp. 603-606. [cited by applicant]
Maurer, “Intraoperatives Monitoring motorischer Hirnnerven bei Operationen an Hals und Schädelbasis”, Laryngo-Rhino-Otologie, vol. 73, No. 11, 1994, pp. 561-567. [cited by applicant]
Moed, “Intraoperative Monitoring with Stimulus-Evoked Electromyography During Placement of Iliosacral Screws. An Initial Clinical Study”, The Journal of Bone and Joint Surgery, vol. 80, No. 4, 1998, pp. 537-546. [cited by applicant]
Moller, Aage R., “Neuromonitoring in Operations in the Skull Base”, The Keio Journal of Medicine, vol. 40, No. 3, 1991, pp. 151-159. [cited by applicant]
Murphy et al., “Micro Electro Mechanical Systems Based Sensor for Mechanomyography”, 19th International Conference Biosignal, 2008, 10 pages. [cited by applicant]
Nijsen et al., “Model for Arm Movements During Myoclonic Seizures”, Proceedings of the 29th Annual International Conference of the IEEE EMBS, Lyon, France, Aug. 23-26, 2007, pp. 1582-1585. [cited by applicant]
Ohta et al., “Superimposed Mechanomyographic Response at Different Contraction Intensity in Medial Gastrocnemius and Soleus Muscles”, International Journal of Sport and Health Science, vol. 5, 2007, pp. 63-70. [cited by applicant]
Sugita et al., “Technical and Instrumental Improvements in the Surgical Treatment of Acoustic Neurinomas”, Journal of Neurosurgery, vol. 57, No. 6, 1982, pp. 747-752. [cited by applicant]
Tarata et al., “The Accelerometer MMG Measurement Approach, in Monitoring the Muscular Fatigue”, Measurement Science Review, vol. 1, No. 1, 2001, pp. 47-50. [cited by applicant]
Welch et al., “Evaluation with Evoked and Spontaneous Electromyography During Lumbar Instrumentation: A Prospective Study”, Journal of Neurosurgery, vol. 87, No. 3, 1997, pp. 397-402. [cited by applicant]
Witt, Robert L., “Facial Nerve Monitoring in Parotid Surgery: The Standard of Care?”, Otolaryngology—Head and Neck Surgery, vol. 119, No. 5, Nov. 1998, pp. 468-470. [cited by applicant]
Yingling et al., “Intraoperative Monitoring of Facial and Cochlear Nerves During Acoustic Neuroma Surgery”, Otolaryngologic Clinics of North America, vol. 25, No. 2, 1992, pp. 413-448. [cited by applicant]
Young et al., “Intraoperative Stimulation of Pedicle Screws: A New Method for Verification of Screw Placement”, Surgical Neurology, vol. 44, No. 6, Dec. 1, 1995, pp. 544-547. [cited by applicant]
Bron Elektronik AG, “bronControl”, Retrieved Dec. 26, 2023, from “https://broncontrol.en.aptoide.com/app”, Aug. 7, 2021, 10 pages. [cited by applicant]
Steris Healthcare, Knowledge Center, “COVID-19 Changed the Operating Room”, Retrieved Mar. 25, 2024, from: “https://www.steris.com/healthcare/knowledge-center/surgical-equipment/or-integration-for-modern-operating-room”… [cited by applicant]
DePuy Synthes, “Sentio MMG Global IFU—English: Version A”, Retrieved Jan. 5, 2024, from: “https://www.e-ifu.com/franchise-landing/V0G000000000208/product-family/V0F000000000292/00P000000000N57”, Feb. 7, 2020, 13 pages. [cited by applicant]
DePuy Synthes, “Sentio MMG: Version B”, Retrieved Jan. 5, 2024, from: “https://www.e-ifu.com/franchise landing/V0G000000000208/product-family/V0F000000000292/00P000000000N57”, Mar. 27, 2019, 10 pages. [cited by applicant]
DePuy Synthes, “Defining the Line between Noise and Nerve Status”, Retrieved Jan. 5, 2024, from: “https://www.jnjmedtech.com/sites/default/files/user_uploaded_assets/pdf_assets/2021-07/140014-200512%20DSUS.EMEA%20Sentio… [cited by applicant]
DePuy Synthes Companies, “DePuy Synthes Spine SENTIO MMG Redefining Nerve Status”, Retrieved Dec. 22, 2023, from https://www.youtube.com/watch?v=5l8wlvJEdcs, Oct. 14, 2020, 2 pages. [cited by applicant]