IP Library › Granted Patent US 12,303,588
Granted Patent B2
US 12,303,588 · App. 17/831,558 · Granted May 20, 2025

Composition containing

Inventors: Min Kyung Kim (Seongnam-si, KR); Da Hee Son (Yongin-si, KR); Seoung Woo Shin (Seongnam-si, KR); Eun Sun Jung (Suwon-si, KR); Deok Hoon Park (Seongnam-si, KR)
Assignee: BIOSPECTRUM, INC.
A61K8/9789A61K36/28A61Q5/10A61Q19/04A61K2800/78
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Quick Facts
Patent No.
US 12,303,588
App. No.
17/831,558
Granted
May 20, 2025
Kind
B2
Abstract

The present invention relates to a composition for stimulating melanogenesis, comprising Cirsium japonicum extract as an effective ingredient. The composition has no skin irritation and cytotoxicity and is excellent in human stability and very effective in stimulating melanogenesis. Therefore, the composition can be safely used in cosmetic or pharmaceutical composition for preventing, improving or treating vitiligo, white hair or hypopigmentation.

Claims (6)

1. A method for stimulating melanogenesis, comprising administering a composition which comprises Cirsium japonicum flower extract as an effective ingredient to a patient in need thereof.

2. A method for preventing or reducing vitiligo, white hair or hypopigmentation, comprising administering a composition which comprises Cirsium japonicum flower extract as an effective ingredient to a patient in need thereof.

3. The method according to claim 2 , wherein the flower Cirsium japonicum extract is comprised in an amount of 0.0001 to 15% by weight, based on the total weight of the composition.

4. The method according to claim 2 , wherein the composition has a formulation selected form the group consisting of a solution, a suspension, an emulsion, a paste, a gel, a cream, a lotion, a powder, a soap, a surfactant-containing cleanser, an oil, a powder foundation, an emulsion foundation, a wax foundation, and a spray.

5. A method for preventing or treating vitiligo, white hair or hypopigmentation, comprising administering a composition which comprises Cirsium japonicum flower extract as an effective ingredient to a patient in need thereof.

6. The method according to claim 5 , wherein the Cirsium japonicum flower extract is comprised in an amount of 0.0001 to 15% by weight, based on the total weight of the composition.

Priority Claims (1)
KR 10-2017-0035571 · Mar 21, 2017 · national
Continuity (2)
Division 16496565
Related Publication 20220287956A1 · Sep 15, 2022
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