IP Library › Granted Patent US 12,303,625
Granted Patent B2
US 12,303,625 · App. 17/369,127 · Granted May 20, 2025

Method for extracorporeal blood purification and dialysate disposal

Inventor: Alexander Rohde (Melsungen, DE)
Assignee: B. Braun Avitum AG
A61M1/14A61J1/10A61J1/1475A61M1/1668A61J1/2003A61M1/287A61M1/3621
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Quick Facts
Patent No.
US 12,303,625
App. No.
17/369,127
Granted
May 20, 2025
Kind
B2
Abstract

A method for extracorporeal blood purification and dialysate disposal includes the steps of: passing a patient's blood through a dialyzer through a first line, passing dialysate through the dialyzer through a second line so that the dialysate exits the dialyzer as used dialysate, and collecting the used dialysate in a container. The container can include an inlet and an outlet connector, the inlet being fluidly connected to the dialyzer to receive the used dialysate, and the outlet connector being fluidly connected to a sewer line of a sewage system in a sealed manner to discharge the used dialysate directly into the sewage system.

Claims (19)

1. A method for extracorporeal blood purification and dialysate disposal, the method comprising the steps of:

passing a patient's blood through a dialyzer through a first line;

passing dialysate through the dialyzer through a second line so that the dialysate exits the dialyzer as used dialysate;

collecting the used dialysate in a container, the container comprising an inlet and an outlet connector, the inlet being fluidly connected to the dialyzer to receive the used dialysate, and the outlet connector being fluidly connected to a sewer line of a sewage system in a sealed manner to discharge the used dialysate directly into the sewage system; and

discharging the used dialysate through the outlet connector and into the sewage system,

wherein the step of discharging the used dialysate through the outlet connector and into the sewage system comprises the step of inducing a pressure gradient between the container and the outlet connector to remove the used dialysate from the container,

wherein the step of inducing a pressure gradient between the container and the outlet connector to remove the used dialysate from the container comprises inducing a pressure drop in the outlet connector to remove the used dialysate from the container by suction, and

wherein the outlet connector is attached to an auxiliary line that delivers a water jet into the outlet connector.

2. The method of claim 1 , wherein the sewer line is located in a hospital, and the dialyzer is connected to a mobile dialysis machine that is movable to different treatment locations in the hospital.

3. The method of claim 1 , wherein the container comprises a flexible bag.

4. The method of claim 1 , wherein the outlet connector comprises a connection that connects the outlet connector to the container.

5. The method of claim 4 , wherein the connection comprises an inserting pin, the inserting pin having a tip configured to pierce the container.

6. The method of claim 4 , wherein the connection comprises a Luer lock or Walther coupling.

7. The method of claim 4 , wherein the connection is integrally formed with the container as one piece.

8. The method of claim 1 , wherein the auxiliary line comprises a tapered section, and wherein the step of inducing a pressure drop in the outlet connector comprises delivering water through the tapered section to create the pressure drop and remove the used dialysate from the container by suction.

9. The method of claim 1 , wherein the outlet connector comprises a Venturi nozzle, and wherein the step of inducing a pressure drop in the outlet connector comprises delivering water through the Venturi nozzle to create the pressure drop and remove the used dialysate from the container by suction.

10. The method of claim 1 , wherein the step of discharging the used dialysate through the outlet connector and into the sewage system is carried out until the container is empty.

11. The method of claim 10 , further comprising the step of disposing of the container after the container is empty.

12. The method of claim 11 , wherein the step of disposing of the container after the container is empty comprises removing the container from an outer packaging that acts as a sterile barrier around the container while the container collects the used dialysate.

Priority Claims (1)
DE 10 2017 116 394.8 · Jul 20, 2017 · national
Continuity (2)
Continuation 16039971 · Jul 19, 2018
Related Publication 20210330551A1 · Oct 28, 2021
References Cited (106)
US 3515275A · Bowman · 1970 [cited by applicant]
US 3528550A · Cappelen, Jr. · 1970 [cited by applicant]
US 4316466A · Babb · 1982 [cited by applicant]
US 4326526A · Buck et al. · 1982 [cited by applicant]
US 4991743A · Walker · 1991 [cited by applicant]
US 5281202A · Weber et al. · 1994 [cited by applicant]
US 5685385A · Sanuga · 1997 [cited by applicant]
US 5685835A · Brugger · 1997 [cited by examiner]
US 5713850A · Heilmann et al. · 1998 [cited by applicant]
US 5722947A · Jeppsson et al. · 1998 [cited by applicant]
US 5954951A · Nuccio · 1999 [cited by applicant]
US 6039060A · Rower · 2000 [cited by applicant]
US 6039718A · Niedospial, Jr. · 2000 [cited by examiner]
US 6310151B1 · Windisch et al. · 2001 [cited by applicant]
US 6558340B1 · Traeger · 2003 [cited by applicant]
US 8025173B2 · Michaels · 2011 [cited by applicant]
US 8226595B2 · Childers et al. · 2012 [cited by applicant]
US 8460544B2 · Völker · 2013 [cited by applicant]
US 9033948B2 · Payrat · 2015 [cited by examiner]
US 9717837B2 · Vincent · 2017 [cited by applicant]
US 10238855B2 · Weber et al. · 2019 [cited by applicant]
US 10252856B2 · Michaels et al. · 2019 [cited by applicant]
US 20030230340A1 · Anderson et al. · 2003 [cited by applicant]
US 20040036185A1 · Garcia · 2004 [cited by applicant]
US 20040267183A1 · Chevallet · 2004 [cited by applicant]
US 20050001110A1 · Simon · 2005 [cited by applicant]
US 20090182263A1 · Burbank et al. · 2009 [cited by applicant]
US 20090204080A1 · Balteau · 2009 [cited by examiner]
US 20100006048A1 · Minty et al. · 2010 [cited by applicant]
US 20130006171A1 · Griessmann · 2013 [cited by examiner]
US 20140232020A1 · Sabadicci et al. · 2014 [cited by applicant]
US 20140238912A1 · Vincent · 2014 [cited by applicant]
US 20140378915A1 · Wesseler · 2014 [cited by applicant]
US 20150224245A1 · Payrat et al. · 2015 [cited by applicant]
US 20160008224A1 · Rahimy et al. · 2016 [cited by applicant]
US 20160129173A1 · Ahrens et al. · 2016 [cited by applicant]
US 20210330551A1 · Rohde · 2021 [cited by applicant]
AU 2004248985A1 · 2006 [cited by examiner]
CN 1141006A · 1997 [cited by applicant]
CN 1309572A · 2001 [cited by applicant]
CN 1423576A · 2003 [cited by applicant]
CN 101437604A · 2009 [cited by applicant]
CN 101535129A · 2009 [cited by applicant]
CN 202699702U · 2013 [cited by applicant]
CN 104225781A · 2014 [cited by applicant]
CN 209900233U · 2020 [cited by applicant]
DE 3211895A1 · 1983 [cited by applicant]
DE 3320416A1 · 1984 [cited by applicant]
DE 8505923U1 · 1985 [cited by applicant]
DE 3409457A1 · 1985 [cited by applicant]
DE 3911587A1 · 1990 [cited by applicant]
DE 19528160A1 · 1997 [cited by applicant]
DE 19537271A1 · 1997 [cited by applicant]
DE 202004016882U1 · 2005 [cited by applicant]
DE 60310935 · 2007 [cited by applicant]
DE 102009038574A1 · 2011 [cited by applicant]
DE 102009038571 · 2011 [cited by applicant]
DE 102009038571B · 2011 [cited by applicant]
DE 102013106550A1 · 2014 [cited by applicant]
DE 202016000643U1 · 2016 [cited by applicant]
EP 0303765A1 · 1989 [cited by applicant]
EP 0530667A1 · 1993 [cited by applicant]
EP 0593102A1 · 1994 [cited by applicant]
EP 0715860A1 · 1996 [cited by applicant]
EP 2353629A1 · 2011 [cited by applicant]
EP 2818152A1 · 2014 [cited by applicant]
EP 3017832A1 · 2017 [cited by applicant]
EP 3017832B1 · 2017 [cited by applicant]
FR 2539034A1 · 1984 [cited by applicant]
JP H09313597A · 1997 [cited by applicant]
JP H09323597A · 1997 [cited by applicant]
JP 2010502373A · 2010 [cited by applicant]
JP 2010522061A · 2010 [cited by applicant]
JP 2012179432A · 2012 [cited by applicant]
WO 8810124A1 · 1988 [cited by applicant]
WO 9520985A1 · 1995 [cited by applicant]
WO 0164262A2 · 2001 [cited by applicant]
WO 2009139878A1 · 2009 [cited by applicant]
WO 2013050689A1 · 2013 [cited by applicant]
WO 2013055283A1 · 2013 [cited by applicant]
WO 2013098779A1 · 2013 [cited by applicant]
WO 2015067359A1 · 2015 [cited by applicant]
Office Action received in Chinese Application No. 201810802122.0 dated Jun. 15, 2023, with translation, 12 pages. [cited by applicant]
Final Office Action received in U.S. Appl. No. 16/039,971 dated Mar. 30, 2022, 16 pages. [cited by applicant]
Office Acton received in Chinese Application No. 201810802122.0 dated May 7, 2022, with translation, 26 pages. [cited by applicant]
Office Action received in Chinese Application No. 201810802122.0 dated Jan. 28, 2023, with translation, 23 pages. [cited by applicant]
Haemodialysis, MSR Media Supply Rail, flyer of Fresenius Medical Care Deutschland GmbH, 2012, without reservation at the Industrial Exhibition of the 50th ERA-EDTA Congress, May 18-21, 2013, at the ICCC Istanbul Congres… [cited by applicant]
Photo of a package surrounding the bag shown in the D10-D13 and D19, multiFiltrate bag with year of manufacture 2015 from the rear side. [cited by applicant]
Photo of a package surrounding the bag shown in the D10-D13 and D19, multiFiltrate bag with year of manufacture 2015 from the frong side. [cited by applicant]
Popp, “Law, structure and behavior—experiences from Germany,” Presentation Malta, Mar. 13, 2014, 15 pages. [cited by applicant]
Ronco, et al., “Critical Care Nephrology,” Kluwer Academic Publishers, Critical Care Nephrology, published 1998, 53 pages. [cited by applicant]
Summons to Oral Proceedings received in European Application No. 18184208.9-1113 dated Dec. 20, 2021, with translation, 23 pages. [cited by applicant]
Acute Therapy Systems, multiFiltratePRO, A perfect fit for every team, Ci-Ca multiIntenseCare, Fresenius Medical Care, Germany, 2015, 20 pages. [cited by applicant]
Acute Therapy Systems, multiFiltratePRO, Supporting your clinical practice, Ci-Ca multiIntenseCare, Fresenius Medical Care, 2015, 12 pages. [cited by applicant]
Acute Therapy Systems, Product Range, Fresenius Medical Care, Jul. 2010, 26 pages. [cited by applicant]
Acute Therapy Systems, The multiFiltrate system: Your choice for optimal therapy, Fresenius Medical Care, 2015, 16 pages. [cited by applicant]
Baldwin, et al., “Clinical Nursing for the Application of Continuous Renal Replacement Therapy in the Intensive Care Unit,” The clinical Application of CRRT—Current Status, Department of Intensive Care, 2009, 5 pages. [cited by applicant]
Baldwin, et al., “Nursing for Renal Replacement Therapies in the Intensive Care Unit: Historical, Educational, and Protocol Review,” Blood Purification, Jan. 14, 2009, 8 pages. [cited by applicant]
Cruz, et al., “Machines for Continuous Renal Replacement Therapy,” The Clinical Application of CRRT—Current Status, Department of Nephrology, 2009, 10 pages. [cited by applicant]
Extended European Search Report for European Application No. 18 184 208.9, dated Dec. 12, 2018, with translation, 10 pages. [cited by applicant]
Fresenius Medical Care: Acute Therapy Systems—Multi Filtrate Ci-Ca Total Solution for Citrate Anticoagulation, Jun. 2014, Sydney, Australia (AP391/AT/AU/2014)—8 pages. [cited by applicant]
German Search Report for Application No. 10 2017 116 394.8, dated Mar. 5, 2018, with English translation—15 pages. [cited by applicant]
Office Action received in European Application No. 18184208.9-1113, dated Apr. 22, 2021, with translation, 94 pages. [cited by applicant]
Office Action received in Japanese Application No. 2018-136673 dated Feb. 3, 2021, with translation, 4 pages. [cited by applicant]
Ronco, et al., “Continuous Renal Replacement Therapy: Opinions and Evidence,” Advances in Renal Replacement Therapy, vol. 9, No. 4., Oct. 2002, 16 pages. [cited by applicant]
Office Action received in U.S. Appl. No. 16/039,971, filed Jan. 14, 2022, 10 pages. [cited by applicant]