Gut microbes against infectious diseases and its use
Gut microbes to provide a preventive or therapeutic effect on infectious diseases caused by pathogenic microorganisms and uses thereof are discussed. The gut microbes resistant are characterized in that they are selected from the group consisting of Oribacterium species JBO3-101 (accession number KACC 81250BP) and Ruminococcus species JBR5-501 (accession number KACC 81249BP). The gut microbes according to the present disclosure have the effect of rendering the host resistant to infectious diseases caused by pathogenic microorganisms when the microbes are ingested.
1. A gut microbe resistant against infectious diseases, consisting of Oribacterium species JBO3-101 strain (accession number KACC 81250BP) and Ruminococcus species JBR5-501 strain (accession number KACC 81249BP).
2. The gut microbe of claim 1 , wherein the gut microbe has a preventive or therapeutic effect on an infectious disease caused by a pathogenic microorganism.
3. A composition for preventing or treating an infectious disease, wherein the composition comprises, as an active ingredient, a gut microbe resistant against infectious diseases consisting of Oribacterium species JBO3-101 strain (accession number KACC 81250BP) and Ruminococcus species JBR5-501 strain (accession number KACC 81249BP) or cultures thereof.
4. The composition of claim 3 , wherein the infectious disease is a disease caused by infection with a pathogenic virus, a pathogenic bacterium, or a pathogenic fungus.
5. The composition of claim 3 , wherein the Oribacterium species JBO3-101 strain is at a concentration of 10 3 to 10 12 CFU/g and the Ruminococcus species JBR5-501 strain is at a concentration of 10 3 to 10 12 CFU/g.
6. The composition of claim 3 , wherein the Oribacterium species JBO3-101 strain is administered at a dose of 1×10 9 CFU/100 μL PBS/day and the Ruminococcus species JBR5-501 strain is administered at a dose of 1×10 9 CFU/100 μL PBS/day.