Methods of making antimicrobial compositions and/or virucidal disinfectant compositions from vegetable oil, and related antimicrobial compositions and/or virucidal disinfectant compositions and uses
The present disclosure relates to methods and systems for making one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions. Said methods and systems include exposing a vegetable oil composition to ozone gas to cause ozonolysis of on one or more unsaturated fatty acids present in the vegetable oil composition, thereby forming an ozonated vegetable oil composition and exposing the ozonated vegetable oil composition to a temperature greater than 60° C. while in contact with water to decompose one or more ozonide compounds and form a heat-treated, ozonated vegetable oil composition. The present disclosure also relates to one or more uses of said one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions.
1. A method of making one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions, wherein the method comprises:
a) exposing a vegetable oil composition to ozone gas to cause ozonolysis of one or more unsaturated fatty acids present in the vegetable oil composition, thereby forming an ozonated vegetable oil composition, wherein the ozonated vegetable oil composition comprises one or more ozonide compounds;
b) exposing the ozonated vegetable oil composition to a temperature greater than 60° C. while in contact with water to decompose one or more ozonide compounds and form a heat-treated, ozonated vegetable oil composition comprising a carboxylic acid chosen from a C1 carboxylic acid, a C2 carboxylic acid, a C3 carboxylic acid, a C4 carboxylic acid, and mixtures thereof, wherein the heat-treated, ozonated vegetable oil composition comprises an aqueous phase and an oil phase; and
c) separating at least a portion of the aqueous phase from the heat-treated, ozonated vegetable oil composition, wherein the at least a portion of the aqueous phase from the heat-treated, ozonated vegetable oil composition is an antimicrobial composition and/or virucidal disinfectant composition comprising a carboxylic acid chosen from a C1 carboxylic acid, a C2 carboxylic acid, a C3 carboxylic acid, a C4 carboxylic acid, and mixtures thereof.
2. The method of claim 1 , wherein exposing a vegetable oil composition to ozone gas occurs while the vegetable oil composition is maintained at a temperature from greater than 0° C. to 60° C.
3. The method of claim 1 , wherein exposing a vegetable oil composition to ozone gas occurs for time period from 1 minute to 20 hours.
4. The method of claim 1 , wherein exposing a vegetable oil composition to ozone gas occurs via a batch and/or a continuous process.
5. The method of claim 1 , wherein exposing a vegetable oil composition to ozone gas is chosen from sparging ozone gas into the vegetable oil composition, mixing ozone gas from a headspace into the vegetable oil composition, contacting ozone gas with the vegetable oil composition in a counter-current manner, and combinations thereof.
6. The method of claim 1 , wherein exposing a vegetable oil composition to ozone gas occurs under a vacuum, at atmospheric pressure, or at a pressure greater than atmospheric pressure.
7. The method of claim 1 , wherein exposing the ozonated vegetable oil composition to a temperature greater than 60° C. comprises exposing the ozonated vegetable oil composition to temperature from 80° C. to 100° C.
8. The method of claim 1 , wherein exposing the ozonated vegetable oil composition to a temperature greater than 60° C. occurs for a time period from 1 minute to 48 hours.
9. The method of claim 1 , further comprising a time period between steps “a” and “b,” wherein the time period is less than 2 hours, and wherein ozone gas is not introduced into the ozonated vegetable oil composition during the time period.
10. The method of claim 1 , wherein ozone gas is not introduced into the ozonated vegetable oil composition while exposing the ozonated vegetable oil composition to a temperature greater than 60° C.
11. The method of claim 1 , wherein, after exposing the vegetable oil composition to ozone gas, washing the vegetable oil composition with an aqueous composition to form the ozonated vegetable oil composition comprising the aqueous phase and the oil phase.
12. The method of claim 1 , wherein the vegetable oil composition is exposed to ozone gas while in contact with water.
13. The method of claim 1 , further comprising adding an aqueous composition to the vegetable oil composition prior to exposing the vegetable oil composition to ozone gas, wherein, after adding an aqueous composition, the vegetable oil composition comprises a weight ratio of vegetable oil component to water in the range from 1:0.1 to 1:10.
14. The method of claim 1 , further comprising washing the heat-treated, ozonated vegetable oil composition with an aqueous composition.
15. The method of claim 1 , wherein the vegetable oil composition is derived from one or more process streams of a biorefinery, wherein the one or more process streams are chosen from whole stillage, thin stillage, syrup, oil emulsion, oil product, and combinations thereof.
16. The method of claim 1 , wherein at least a portion of the oil phase from the heat-treated, ozonated vegetable oil composition is an antimicrobial composition and/or a virucidal disinfectant composition.
17. The method of claim 1 , wherein the vegetable oil composition comprises a vegetable oil component chosen from corn oil, soybean oil, rape seed oil, sunflower oil, olive oil, castor bean oil, and combinations thereof.
18. The method of claim 1 , wherein the ozonated vegetable oil composition has a concentration of ozone gas of one percent or less by weight of the ozonated vegetable oil composition while exposing the ozonated vegetable oil composition to a temperature greater than 60° C.
19. The method of claim 1 , further comprising adding water to the vegetable oil composition prior to exposing the vegetable oil composition to ozone gas, wherein, after adding the water, the vegetable oil composition comprises a weight ratio of vegetable oil component to water in the range from 1:0.5 to 1:10.
20. A method of making one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions, wherein the method comprises:
a) exposing a vegetable oil composition to ozone gas to cause ozonolysis of one or more unsaturated fatty acids present in the vegetable oil composition, thereby forming an ozonated vegetable oil composition, wherein the ozonated vegetable oil composition comprises one or more ozonide compounds;
b) exposing the ozonated vegetable oil composition to a temperature of 60° C. or greater while in contact with water to decompose one or more ozonide compounds via a decomposition reaction and form a heat-treated, ozonated vegetable oil composition, wherein the heat-treated, ozonated vegetable oil composition comprises an aqueous phase and an oil phase, and wherein at least step “b” does not occur in the presence of an exogenous amount of organic solvent that is a product of the decomposition reaction; and
c) separating at least a portion of the aqueous phase from the heat-treated, ozonated vegetable oil composition, wherein the at least a portion of the aqueous phase from the heat-treated, ozonated vegetable oil composition is an antimicrobial composition and/or a virucidal disinfectant composition.