IP Library › Granted Patent US 12,325,849
Granted Patent B2
US 12,325,849 · App. 16/972,178 · Granted Jun 10, 2025

Apparatus and a method for the use of pulsed electromagnetic field to change the condition of a product and/or the generation of said product

Inventors: William John Henry (St. Andrews, GB); Christopher Taylor (Maidenhead, GB)
Assignee: St. Andrews Pharmceutical Technology Ltd.
C12M35/04C12H1/165C12M35/02
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Quick Facts
Patent No.
US 12,325,849
App. No.
16/972,178
Granted
Jun 10, 2025
Kind
B2
Abstract

The invention relates to apparatus and a method to allow the application of an electromagnetic field to a product for a period of time to alter a condition of the product. The condition change may be to speed up an occurring process and/or change quality of the experience of subsequent use of the product. The apparatus includes a support and a container in which the said product is located. The support includes one or more modules for generation of a pulsed electromagnetic field (PEMF) and the support and hence modules are connected to control means to control the generation of the PEMF and are positionable with respect to the said product so as to allow the product to be exposed to the generated PEMF.

Claims (20)

1. A system to allow application of a pulsed electromagnetic wave to a cell culture for a period of time, to alter a condition of the cell culture, said system comprising:

a signal generator configured to generate the pulsed electromagnetic wave;

a controller comprising a control circuit or processor configured to control generation of the pulsed electromagnetic wave;

a container in which the cell culture is located; and

at least one support that includes one or more modules, wherein each module of the one or more modules comprises a transmitter and an antenna arranged for transmission of the pulsed electromagnetic wave towards the container, and said at least one support includes or is connected to said controller, and the at least one support is positioned in proximity to the container so as to allow the cell culture to be exposed to the pulsed electromagnetic wave which is generated; and

wherein the altered condition of the cell culture is a change of metabolic productivity and/or production rate of the cell culture.

2. The system according to claim 1 , wherein the controller is configured to control frequency and pulse sequence of the pulsed electromagnetic wave.

3. The system according to claim 1 , wherein the one or more modules comprise a plurality of the modules provided in a fixed array or configuration on the at least one support.

4. The system according to claim 1 , wherein the container has walls and the at least one support is located externally of the container and the pulsed electromagnetic wave is applied to the cell culture through one or more of the walls of the container in which the cell culture is located.

5. The system according to claim 1 , wherein at least a part of the at least one support is located inside the container or the container has walls and the one or more modules is located within the walls of the container.

6. The system according to claim 1 , wherein the at least one support comprises a plurality of supports that each include the one or more modules, wherein each of the plurality of supports is located at a different locations in proximity to the container, in order to provide the cell culture with a uniform exposure to the pulsed electromagnetic wave.

7. The system according to claim 1 , wherein the transmitter is configured to transmit pulsed electromagnetic waves within an industrial, scientific, and medical (ISM) short-range radio frequency band.

8. The system according to claim 1 , wherein the transmitter is configured to transmit pulsed electromagnetic waves with a frequency of 2.4 GHz.

9. The system according to claim 1 , wherein the transmitter is configured to transmit the pulsed electromagnetic wave up to a distance of 15 metres.

10. The system according to claim 1 , wherein the controller is configured to provide the pulsed electromagnetic wave in pulses which are in a range of 0.5-1.5 ms in duration.

11. The system according to claim 1 , wherein the controller is configured to provide the pulsed electromagnetic wave in pulses that are each spaced apart by a rest period in a range of 40-66 ms.

12. The system according to claim 1 , wherein the controller is configured to provide pulsed electromagnetic wave pulses within a range of 12-20 pulses per second.

13. The system according to claim 1 , wherein the one or more modules are omnidirectional in terms of direction of emission of the pulsed electromagnetic wave in an omnidirectional manner to the cell culture.

14. The system according to claim 1 , wherein the pulsed electromagnetic wave comprises pulses in which transmission power is in the order of microwatts.

15. The system according to claim 1 , wherein the at least one support includes a housing that is transmissive to radio frequency electromagnetic waves, wherein the housing comprises the one or more modules, and wherein the transmitter is configured to transmit electromagnetic waves in a radio frequency band.

Assignments (2)
CHANGE OF NAME Recorded Feb 16, 2021
From: ZENOTOP LIMITED
To: ST ANDREWS PHARMACEUTICAL TECHNOLOGY LTD
Reel/Frame 055274/0708 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER PREVIOUSLY RECORDED AT REEL: 055001 FRAME: 0591. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 25, 2021
From: HENRY, WILLIAM JOHN; TAYLOR, CHRISTOPHER
To: ZENOTOP LIMITED
Reel/Frame 055092/0897 →
Priority Claims (3)
GB 1809355 · Jun 7, 2018 · national
GB 1813537 · Aug 20, 2018 · national
GB 1819886 · Dec 6, 2018 · national
Continuity (1)
Related Publication 20210189317A1 · Jun 24, 2021
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