IP Library › Granted Patent US 12,343,211
Granted Patent B2
US 12,343,211 · App. 17/305,893 · Granted Jul 1, 2025

Ultrasound image analyzing apparatus for quantifying contrast agent stagnation

Inventors: Yuko Takada (Utsunomiya, JP); Masaki Watanabe (Utsunomiya, JP); Yasunori Honjo (Utsunomiya, JP); Yu Igarashi (Utsunomiya, JP)
Assignee: CANON MEDICAL SYSTEMS CORPORATION
A61B8/5207A61B8/06A61B8/463A61B8/481A61B8/5253
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Quick Facts
Patent No.
US 12,343,211
App. No.
17/305,893
Granted
Jul 1, 2025
Kind
B2
Abstract

An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to generate contrast image data on the basis of a contrast signal acquired from an examined subject to whom a contrast agent is administered. The processing circuitry is configured to generate blood flow image data on the basis of a blood flow signal estimated by performing a filtering process on the contrast signal. The processing circuitry is configured to output information indicating a region where the contrast agent is stagnant within a region of interest, on the basis of the contrast image data and the blood flow image data.

Claims (44)

1. An image analyzing apparatus, comprising:

processing circuitry configured to

generate contrast image data based on a contrast signal acquired from an examined subject to whom a contrast agent is administered;

generate blood flow image data based on a blood flow signal estimated by performing a filtering process on the contrast signal;

identify a stagnant region of the contrast agent where the contrast agent is present and the blood flow is absent in a region of interest, by subtracting the blood flow image data from the contrast image data; and

output information indicating the identified region.

2. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to identify, as the region, a region having the contrast signal but not having the blood flow signal within the region of interest.

3. The image analyzing apparatus according to claim 1 , wherein

the region is a first region having the contrast signals but not having the blood flow signals, and

the processing circuitry is further configured to identify a second region having both the contrast signal and the blood flow signal, based on the contrast image data and the blood flow image data.

4. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to perform a contrast-purpose ultrasound scan to acquire the contrast signal from a first scan region of the examined subject and to perform a blood-flow-purpose ultrasound scan to acquire the blood flow signal from a second scan region overlapping with the first scan region at least partially.

5. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to

generate tracking image data based on a vector expressing a chronological movement of a contrast agent bubble, and

display the tracking image data.

6. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to cause, as the information, the region to be displayed by at least one of the contrast image data and the blood flow image data.

7. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to display, as the information, a graph indicating a chronological change of a pixel value in the region.

8. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to display, as the information, an area ratio of the region to the region of interest.

9. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to display, as the information, an area ratio of a second region having the contrast signal and the blood flow signal to a region having the contrast signal.

10. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to display, as the information, an area ratio of a third region having a blood flow speed higher than a threshold value, to a second region having the contrast signal and the blood flow signal.

11. The image analyzing apparatus according to claim 1 , wherein the processing circuitry is further configured to display, as the information, an area ratio of a fourth region having a blood flow speed lower than a threshold value, to a second region having the contrast signal and the blood flow signal.

12. The image analyzing apparatus according to claim 1 , wherein

the region is a first region, and

the processing circuitry is further configured to simultaneously display two or more graphs selected from among the following, as the information:

a graph indicating a chronological change of a pixel value in a region having a contrast signal of the contrast image data;

a graph indicating a chronological change of a pixel value in a region having a blood flow signal of the blood flow image data;

a graph indicating a chronological change of a pixel value in a third region having a blood flow speed higher than a threshold value;

a graph indicating a chronological change of a pixel value in a fourth region having a blood flow speed lower than a threshold value;

a graph indicating a chronological change of an area ratio of a region having the contrast signal to the region of interest;

a graph indicating a chronological change of an area ratio of a region having the blood flow signal to the region of interest;

a graph indicating a chronological change of an area ratio of the first region to the region of interest;

a graph indicating a chronological change of an area ratio of a second region having the contrast signal and the blood flow signal, to a region having the contrast signal;

a graph indicating a chronological change of an area ratio of a region having a blood flow speed higher than a threshold value, to a second region having the contrast signal and the blood flow signal;

a graph indicating a chronological change of an area ratio of a region having a blood flow speed lower than a threshold value, to a second region having the contrast signal and the blood flow signal;

a graph indicating a chronological change of an average speed of contrast agent bubbles in the region of interest;

a graph indicating a chronological change of an average speed of contrast agent bubbles in the first region; and

a graph indicating a chronological change of an average speed of contrast agent bubbles in a region having the blood flow signal.

13. The image analyzing apparatus according to claim 1 , the image analyzing apparatus being an ultrasound diagnosis apparatus.

14. The image analyzing apparatus according to claim 1 , wherein the contrast signal is a signal of a harmonic component acquired from the examined subject to whom the contrast agent is administered.

15. The image analyzing apparatus according to claim 1 , wherein the filtering process is a filtering process to eliminate a principal component of a signal change in a frame direction.

16. An image analyzing apparatus, comprising:

processing circuitry configured to

generate contrast image data based on a contrast signal acquired from an examined subject to whom a contrast agent is administered;

generate tracking image data indicating a chronological movement of individual contrast agent bubbles; and

output, based on the contrast image data and the tracking image data, information indicating a region which has the contrast signal and in which an average speed of the contrast agent bubbles is smaller than a threshold value, within a region of interest.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2021
From: TAKADA, YUKO; WATANABE, MASAKI; HONJO, YASUNORI; IGARASHI, YU
To: CANON MEDICAL SYSTEMS CORPORATION
Reel/Frame 056882/0014 →
Priority Claims (1)
JP 2019-006215 · Jan 17, 2019 · national
Continuity (2)
Continuation PCTJP2020000286 · Jan 8, 2020
Related Publication 20210338207A1 · Nov 4, 2021
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