IP Library › Granted Patent US 12,343,257
Granted Patent B2
US 12,343,257 · App. 18/436,319 · Granted Jul 1, 2025

Prolapse prevention device and methods of use thereof

Inventors: Niall Duffy (Galway, IE); David Farascioni (Bethel, CT); Adam Fitzgerald (St. Louis Park, MN); Nathan Knutson (Long Lake, MN); Ana Menk (Shoreview, MN); Aran Murray (Galway, IE); Jay Rassat (Buffalo, MN)
Assignee: Medtronic Vascular, Inc.
A61F2/2454A61F2/2466A61F2210/0014A61F2220/0008A61F2220/0091A61F2250/001
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Quick Facts
Patent No.
US 12,343,257
App. No.
18/436,319
Granted
Jul 1, 2025
Kind
B2
Abstract

A prolapse prevention device formed by a continuous wire-like structure having a first end and a second end disconnected from each other. The continuous wire-like structure is substantially straight in a delivery configuration. The prolapse prevention device in a deployed configuration includes a centering ring of the continuous wire-like structure configured to seat adjacent to and upstream of an annulus of a heart valve in situ, a vertical support of the continuous wire-like structure which extends from the centering ring and includes an apex configured to seat against a roof of an atrium in situ, and a leaflet backstop of the continuous wire-like structure extending radially inward from the centering ring and configured to contact at least at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.

Claims (37)

1. A prolapse prevention device for treating valvular regurgitation in a heart valve, the prolapse prevention device comprising:

a continuous wire-like structure having a first end and a second end that opposes the first end, the first end and the second end being disconnected from each other,

wherein the continuous wire-like structure of the prolapse prevention device in a deployed configuration includes

a centering ring configured to seat adjacent to and upstream of an annulus of the heart valve to circumferentially center the prolapse prevention device in situ,

a vertical support extending from the centering ring in an upstream direction such that an apex thereof is configured to seat against the atrium and above the annulus of the mitral valve in situ, wherein the vertical support extends longitudinally and non-circumferentially from the centering ring to the roof of the atrium to minimize obstruction within the atrium and wherein the vertical support is curved and configured to abut against a sidewall of the atrium, and

a leaflet backstop extending radially inward from the centering ring and configured to contact at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium, and

wherein the continuous wire-like structure from the first end to the second end is substantially straight in a delivery configuration.

2. The prolapse prevention device of claim 1 , wherein the heart valve is a mitral heart valve and the first leaflet is a posterior leaflet of the mitral heart valve.

3. The prolapse prevention device of claim 1 , wherein the prolapse prevention device is a unitary structure formed from a single piece of material.

4. The prolapse prevention device of claim 1 , wherein the continuous wire-like structure is formed from a self-expanding material and is pre-set in the deployed configuration.

5. The prolapse prevention device of claim 1 , wherein the centering ring is an open ring and the continuous wire-like structure further includes an inner tail that conforms to an inner surface of the centering ring.

6. The prolapse prevention device of claim 5 , wherein the inner tail is configured to permit the open ring to self-adjust to a size of the annulus of the heart valve.

7. The prolapse prevention device of claim 6 , wherein the first end and the inner tail lie within the same plane as the centering ring when the prolapse prevention device is in the deployed configuration.

8. The prolapse prevention device of claim 1 , wherein the centering ring lies within a first plane and the leaflet backstop lies within a second plane when the prolapse prevention device is in the deployed configuration, the second plane being at an angle between fifteen degrees and seventy-five degrees from the first plane.

9. The prolapse prevention device of claim 1 , wherein the leaflet backstop has one of a cross configuration, a circular configuration, and a sinusoidal configuration.

10. The prolapse prevention device of claim 1 , wherein the centering ring lies within a first plane and the vertical support lies within a third plane when the prolapse prevention device is in the deployed configuration, the third plane being at an angle between forty-five degrees and eighty degrees from the first plane.

11. The prolapse prevention device of claim 10 , wherein the first plane is configured to be substantially parallel to a plane of the annulus of the heart valve.

12. The prolapse prevention device of claim 1 , wherein the centering ring lies within a first plane and the vertical support lies within a third plane when the prolapse prevention device is in the deployed configuration, the third plane being at an angle between eighty degrees and one hundred degrees from the first plane.

13. The prolapse prevention device of claim 1 , wherein the continuous wire-like structure further includes a retrieval arm extending from the apex of the vertical support in a downstream direction, away from the roof of the atrium.

14. A method of treating heart valvular regurgitation with a system including a delivery catheter and a prolapse prevention device, the method comprising:

percutaneously introducing the system into a vasculature;

delivering the system through the vasculature to a heart valve with the prolapse prevention device in a delivery configuration, wherein the prolapse prevention device is formed by a continuous wire-like structure having a first end and a second end that opposes the first end, the first end and the second end being disconnected from each other, wherein the continuous wire-like structure from the first end to the second end is substantially straight in the delivery configuration;

positioning a distal end of the delivery catheter adjacent to an annulus of the heart valve; and

deploying the prolapse prevention device such that a centering ring of the continuous wire-like structure is seated adjacent to and upstream of the annulus of the heart valve, a vertical support of the continuous wire-like structure extends from the centering ring in an upstream direction such that an apex thereof is seated against a roof of the atrium, the vertical support extending longitudinally and non-circumferentially from the centering ring to the roof of the atrium to minimize obstruction within the atrium, and a leaflet backstop of the continuous wire-like structure is extending radially inward from the centering ring and contacts at least a first leaflet of the heart valve to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.

15. The method of claim 14 , wherein the vertical support is substantially straight and only the apex thereof abuts against a sidewall of the atrium after the step of deploying the prolapse prevention device.

16. The method of claim 14 , wherein the vertical support is curved and abuts against a sidewall of the atrium after the step of deploying the prolapse prevention device.

17. A method of treating heart valvular regurgitation with a system including a delivery catheter and a prolapse prevention device, the method comprising:

percutaneously introducing the system into a vasculature;

delivering the system through the vasculature to a heart valve with the prolapse prevention device in a delivery configuration, wherein the prolapse prevention device is formed by a continuous wire-like structure having a first end and a second end that opposes the first end, the first end and the second end being disconnected from each other;

positioning a distal end of the delivery catheter adjacent to an annulus of the heart valve;

deploying the prolapse prevention device such that a centering ring of the continuous wire-like structure is seated adjacent to and upstream of the annulus of the heart valve, a vertical support of the continuous wire-like structure extends from the centering ring in an upstream direction such that an apex thereof is seated against a roof of the atrium, the vertical support extending longitudinally and non-circumferentially from the centering ring to the roof of the atrium to minimize obstruction within the atrium, and a leaflet backstop of the continuous wire-like structure is extending radially inward from the centering ring and contacts at least a first leaflet of the heart valve to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium;

percutaneously introducing a valve delivery device into a vasculature, the valve delivery device including a valve prosthesis disposed at a distal end thereof, wherein the valve prosthesis is in a compressed configuration and the step of percutaneously introducing the valve delivery device into the vasculature is performed after the step of deploying the prolapse prevention device;

delivering the valve delivery device through the vasculature to the heart valve;

positioning the valve prosthesis in the compressed configuration within the deployed prolapse prevention device; and

deploying the valve prosthesis within the deployed prolapse prevention device.

18. The method of claim 17 , wherein the valve prosthesis is deployed within the leaflet backstop of the prolapse prevention device.

19. The method of claim 17 , wherein the valve prosthesis is deployed within the centering ring of the prolapse prevention device.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 8, 2024
From: DUFFY, NIALL; FARASCIONI, DAVID; FITZGERALD, ADAM; KNUTSON, NATHAN; MENK, ANA; MURRAY, ARAN; RASSAT, JAY
To: MEDTRONIC VASCULAR, INC.
Reel/Frame 066419/0290 →
Continuity (4)
Division 17674341 · Feb 17, 2022
Continuation 16352976 · Mar 14, 2019
Provisional Application 62645307 · Mar 20, 2018
Related Publication 20240238091A1 · Jul 18, 2024
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