Hemostat reconstitution methods and devices
View Patent ↗A kit and system for use in establishing local hemostasis includes a first and a second syringe. The first syringe is co-loaded with at least one substrate material and at least one hemostatic agent including a membrane separating the substrate material and the hemostatic agent. The second syringe is loaded with a diluent. In an embodiment, the kit or system includes crosslinked gelatin particles and thrombin, and the diluent is saline.
1. A system for administering a hemostatic material to a patient, the system comprising;
a first syringe co-loaded with at least one substrate material and at least one hemostatic agent including a membrane separating said substrate material and said hemostatic agent; and
a second syringe loaded with a diluent.
2. The system of claim 1 , wherein said at least one substrate material comprises a gelatin.
3. The system of claim 2 , wherein said gelatin comprises a cross-linked gelatin.
4. The system of claim 3 , wherein said cross-linked gelatin comprises gelatin granules.
5. The system of claim 1 , wherein said at least one hemostatic agent comprises thrombin.
6. The system of claim 1 , wherein said diluent comprises sterile water.
7. The system of claim 1 , wherein said diluent comprises saline.
8. The system of claim 7 , wherein said saline comprises 0.9% (w/v) NaCl.
9. The system of claim 1 , wherein said substrate material is pre-swollen.
10. The system of claim 1 , wherein said membrane comprises a dissolvable, fragmentable, or friable material.
11. The system of claim 10 , wherein said dissolvable, fragmentable, or friable material comprises a gelatin.
12. A kit for use in establishing local hemostasis, comprising;
a first syringe co-loaded with at least one substrate material and at least one hemostatic agent including a membrane separating said substrate material and said hemostatic agent; and
a second syringe loaded with a diluent.
13. The kit of claim 12 , wherein said at least one substrate material comprises a gelatin.
14. The kit of claim 13 , wherein said gelatin comprises a cross-linked gelatin.
15. The kit of claim 14 , wherein said cross-linked gelatin comprises gelatin granules.
16. The kit of claim 12 , wherein said at least one hemostatic agent comprises thrombin.
17. The kit of claim 12 , wherein said diluent comprises sterile water.
18. The kit of claim 12 , wherein said diluent comprises saline.
19. The kit of claim 18 , wherein said saline comprises 0.9% (w/v) NaCl.
20. The kit of claim 12 , wherein said substrate material is pre-swollen.