Granted Patent B2

US 12,350,029 · App. 17/930,253 · Granted Jul 8, 2025

Inventors: Eric Carlin Howie (Henderson, NV); Mark Bradford Flowers (Los Gatos, CA); Tandhoni Srinivasa Rao (Charlestown, MA); Orville Rey Rule, III (Los Altos Hills, CA); Darpan Dinesh Damani (Milpitas, CA); Guy McIlroy (Los Gatos, CA); John Robert Haggis (San Jose, CA); John Bertram Langley, II (Half Moon Bay, CA); Steven Sven Fastert (Chelmsford, MA); William Frederick Ellersick (Hampton, NH); Dwight David Birdsall (Fort Collins, CO)

Assignee: Life Detection Technologies, Inc.

A61B5/05A61B5/7278A61B5/742G01R29/0814A61B5/024A61B5/0816A61B5/1102A61B5/113A61B5/7225A61B5/725

Abstract

Claims (61)

1. A method of predicting a condition of a human body, comprising:

generating, with an electric field generator, an electric field at a nominal frequency;

measuring one or more properties of the generated electric field at multiple time points during a measuring period to produce a series of respective measurement values, the one or more properties of the electric field changing over time due to interactions with the human body in a reactive near-field region of the electric field;

determining one or more periodic behaviors from one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field;

determining one or more non-periodic behaviors from a disruption in at least one of the one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field;

computing, from at least one of the one or more periodic behaviors and at least one of the one or more non-periodic behaviors, one or more physiological parameters of the human body; and

detecting, from the one or more physiological parameters, one or more symptoms of a condition of the human body.

2. The method of claim 1 , wherein the measuring the one or more properties of the electric field comprises:

measuring changes in the one or more properties of the electric field as the one or more properties change due to the interactions with the human body.

3. The method of claim 1 , wherein the one or more properties comprise one or more of a phase, a frequency, and an amplitude.

4. The method of claim 1 , wherein the one or more non-periodic behaviors comprise at least one of sleep apnea or coughing.

5. The method of claim 1 , wherein the one or more non-periodic behaviors comprise movement of a limb of the human body.

6. The method of claim 1 , wherein the determining the one or more non-periodic behaviors comprises:

determining a disruption in at least one of the one or more periodic behaviors.

7. The method of claim 1 , wherein the determining the one or more periodic behaviors is based at least on one or more time points of the multiple time points that do not include one or more other time points of the multiple time points corresponding to the one or more non-periodic behaviors.

8. The method of claim 1 , wherein the one or more physiological parameters comprise a frequency of coughing, and

wherein the one or more symptoms of the condition comprise the frequency of coughing increasing over a period of days.

9. The method of claim 1 , wherein the one or more physiological parameters comprise a frequency of movement at night, and

wherein the one or more symptoms of the condition comprise the frequency of movement at night increasing over a period of days.

10. The method of claim 1 , wherein the one or more physiological parameters comprise a nighttime resting volume of respiration, and

wherein the one or more symptoms of the condition comprise the nighttime resting volume of respiration decreasing over a period of days.

11. The method of claim 1 , wherein the one or more physiological parameters comprise a nighttime resting heart rate and a nighttime resting respiration rate.

12. The method of claim 1 , wherein the one or more physiological parameters comprise a respiration waveform.

13. The method of claim 1 , wherein the one or more symptoms of the condition comprise heart rate variability changing over a period of days.

14. The method of claim 1 , further comprising:

from the one or more symptoms of the condition, predicting the condition of the human body.

15. The method of claim 14 , wherein the condition is onset of a Chronic Obstructive Pulmonary Disease (COPD) exacerbation.

16. The method of claim 14 , wherein the condition is one of Congestive Heart Failure (CHF) or sleep apnea.

17. A system of predicting a condition of a human body, comprising:

an electric field generator configured to generate an electric field at a nominal frequency;

a detector configured to measure one or more properties of the generated electric field at multiple time points during a measuring period to produce a series of respective measurement values, the one or more properties of the electric field changing over time due to interactions with the human body in a reactive near-field region of the electric field; and

a computation unit configured to:

determine one or more periodic behaviors from one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field,

determine one or more non-periodic behaviors from a disruption in at least one of the one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field,

compute, from at least one of the one or more periodic behaviors and at least one of the one or more non-periodic behaviors, one or more physiological parameters of the human body, and

detect, from the one or more physiological parameters, one or more symptoms of a condition of the human body.

18. The system of claim 17 , wherein the one or more properties comprise one or more of a phase, a frequency, and an amplitude.

19. The system of claim 17 , wherein the one or more periodic behaviors comprise at least one of respiration of the human body or a heartbeat of the human body.

20. The system of claim 17 , wherein the one or more non-periodic behaviors comprise at least one of sleep apnea or coughing.

21. The system of claim 17 , wherein the one or more non-periodic behaviors comprise movement of a limb of the human body.

22. The system of claim 17 , wherein the computation unit is further configured to determine the one or more periodic behaviors based at least on one or more time points of the multiple time points that do not include one or more other time points of the multiple time points corresponding to the one or more non-periodic behaviors.

23. The system of claim 17 , wherein the one or more physiological parameters comprise a frequency of coughing, and

wherein the one or more symptoms of the condition comprise the frequency of coughing increasing over a period of days.

24. The system of claim 17 , wherein the one or more physiological parameters comprise a frequency of movement at night, and

wherein the one or more symptoms of the condition comprise the frequency of movement at night increasing over a period of days.

25. The system of claim 17 , wherein the one or more physiological parameters comprise a nighttime resting volume of respiration, and

wherein the one or more symptoms of the condition comprise the nighttime resting volume of respiration decreasing over a period of days.

26. The system of claim 17 , wherein the one or more physiological parameters comprise a nighttime resting heart rate and a nighttime resting respiration rate.

27. The system of claim 17 , wherein the one or more physiological parameters comprise a respiration waveform.

28. The system of claim 17 , wherein the computation unit is further configured to predict the condition of the human body from the one or more symptoms of the condition.

29. The system of claim 28 , wherein the condition is onset of a Chronic Obstructive Pulmonary Disease (COPD) exacerbation.

30. The system of claim 28 , wherein the condition is one of Congestive Heart Failure (CHF) or sleep apnea.

31. The system of claim 17 , wherein a first portion of the computation unit is co-located with the detector, and a second portion of the computation unit is remotely located from the detector and connected to the first portion of the computation unit over a network;

wherein the first portion of the computation unit is configured to determine the one or more periodic behaviors and the one or more non-periodic behaviors; and

wherein the second portion of the computation unit is configured to detect, from the one or more physiological parameters, one or more symptoms of a condition of the human body.

32. A non-transitory computer-readable medium containing instructions which when executed by a processor perform steps of:

receiving a series of respective measurement values produced from measurements of one or more properties of an electric field at multiple time points during a measuring period, the one or more properties of the electric field changing over time due to interactions with a human body in a reactive near-field region of the electric field, wherein the electric field is generated by an electric field generator at a nominal frequency;

determining one or more periodic behaviors from one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field;

determining one or more non-periodic behaviors from a disruption in at least one of the one or more repeating patterns identified in the series of respective measurement values of the measured one or more properties of the generated electric field;

computing, from at least one of the one or more periodic behaviors and at least one of the one or more non-periodic behaviors, one or more physiological parameters of the human body; and

detecting, from the one or more physiological parameters, one or more symptoms of a condition of the human body.

Assignments (3)

Continuity (11)

References Cited (215)