IP Library Granted Patent US 12,361,539
Granted Patent B2
US 12,361,539 · App. 17/462,020 · Granted Jul 15, 2025

Classification method and classification device for classifying level of AMD

Inventors: Meng-Che Cheng (New Taipei, TW); Ming-Tzuo Yin (New Taipei, TW); Yi-Ting Hsieh (Taipei, TW)
Assignee: Acer Medical Inc.
G06T7/0012A61B3/12A61B5/7267G06V40/193G06V40/197G16H30/40G16H50/20G06T2207/20084G06T2207/30041
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Quick Facts
Patent No.
US 12,361,539
App. No.
17/462,020
Granted
Jul 15, 2025
Kind
B2
Abstract

A classification method and a classification device for classifying a level of an age-related macular degeneration are provided. The classification method includes the following. An object detection model and a first classification model are pre-stored. A fundus image is obtained. A bounding box is generated in the fundus image according to a macula in the fundus image detected by the object detection model. An intersection over union between a predetermined area and the bounding box in the fundus image is calculated. A classification of the fundus image is generated according to the first classification model in response to the intersection over union being greater than a threshold.

Claims (23)

1. An eye examining device for classifying a level of age-related macular degeneration, the eye examining device comprising:

a transceiver;

a camera;

a storage medium, storing an object detection model, a first classification model, and a second classification model different from the first classification model; and

a processor, coupled to the camera, the storage medium and the transceiver, wherein the processor is configured to:

capture a fundus image through the camera;

generate a bounding box in the fundus image according to a macula in the fundus image detected by the object detection model;

calculate an intersection over union between a predetermined area and the bounding box in the fundus image, wherein the fundus image and the predetermined area are rectangles, a center point of the predetermined area is located at a geometric center of the fundus image, a first edge of the predetermined area is distanced from a first boundary of the fundus image by a first distance, and a second edge of the predetermined area is distanced from a second boundary of the fundus image by the first distance, wherein the second edge is an opposite edge of the first edge, and the second boundary is an opposite boundary of the first boundary;

input an image in the bounding box into the first classification model to generate a classification of the fundus image in response to the intersection over union being greater than a threshold, wherein the first classification model was trained by a portion of fundus image;

input the fundus image into the second classification model to generate the classification in response to the intersection over union being less than or equal to the threshold, wherein the second classification model was trained by an entire fundus image; and

output the classification through the transceiver, wherein the classification indicates one of a first stage, a second stage, a third stage, and a fourth stage of the age-related macular degeneration.

2. The eye examining device described in claim 1 , wherein the predetermined area is a first rectangle, and the processor is further configured to:

obtain an eyeball area in the fundus image; and

generate a length of a long edge and a length of a short edge of the first rectangle according to a diameter of the eyeball area.

3. The eye examining device described in claim 1 , wherein the first classification model and the second classification model have a same convolutional neural network architecture.

4. An eye examining method for classifying a level of age-related macular degeneration, the eye examining method comprising:

pre-storing an object detection model, a first classification model, and a second classification model different from the first classification model;

capturing a fundus image through a camera;

generating a bounding box in the fundus image according to a macula in the fundus image detected by the object detection model;

calculating an intersection over union between a predetermined area and the bounding box in the fundus image, wherein the fundus image and the predetermined area are rectangles, a center point of the predetermined area is located at a geometric center of the fundus image, a first edge of the predetermined area is distanced from a first boundary of the fundus image by a first distance, and a second edge of the predetermined area is distanced from a second boundary of the fundus image by the first distance, wherein the second edge is an opposite edge of the first edge, and the second boundary is an opposite boundary of the first boundary;

inputting an image in the bounding box into the first classification model to generate a classification of the fundus image in response to the intersection over union being greater than a threshold, wherein the first classification model was trained by a portion of fundus image;

inputting the fundus image into the second classification model to generate the classification in response to the intersection over union being less than or equal to the threshold, wherein the second classification model was trained by an entire fundus image; and

outputting the classification, wherein the classification indicates one of a first stage, a second stage, a third stage, and a fourth stage of the age-related macular degeneration.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2022
From: ACER INCORPORATED; NATIONAL TAIWAN UNIVERSITY HOSPITAL
To: ACER MEDICAL INC.
Reel/Frame 060360/0912 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2021
From: CHENG, MENG-CHE; YIN, MING-TZUO; HSIEH, YI-TING
To: ACER INCORPORATED; NATIONAL TAIWAN UNIVERSITY HOSPITAL
Reel/Frame 057333/0819 →
Priority Claims (1)
TW 110117544 · May 14, 2021 · national
Continuity (1)
Related Publication 20220366559A1 · Nov 17, 2022
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