IP Library › Granted Patent US 12,377,206
Granted Patent B2
US 12,377,206 · App. 18/666,217 · Granted Aug 5, 2025

Fluidics control system for multi catheter stack

Inventors: Kyle Bartholomew (Campbell, CA); Tabish Mustufa (Sunnyvale, CA); Vedant Chhaya (Campbell, CA)
Assignee: Imperative Care, Inc.
A61M5/007A61M5/1408A61M5/1411A61M5/14212A61M5/16827A61M5/16831A61M2205/3393
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Quick Facts
Patent No.
US 12,377,206
App. No.
18/666,217
Granted
Aug 5, 2025
Kind
B2
Abstract

A fluidics system includes a cassette having a saline subsystem, a contrast subsystem, and a vacuum subsystem. The fluidics system further includes a splitter and a first tubing set coupled to the cassette and splitter, the first tubing set having a single saline channel, a single contrast channel, and a single vacuum channel. The fluidics system further includes two or more hub assemblies, at least one of the two or more hub assemblies configured to have a third saline flow-path, a third contrast flow-path, and a third vacuum flow-path to provide saline, contrast and vacuum to the lumen of a catheter coupled to the at least one of the two or more hub assemblies. The fluidics system further includes a second tubing set having a plurality of tube groups, each tube group coupled to the splitter and to one of the two or more hub assemblies.

Claims (39)

1. A fluidics system, comprising:

a cassette configured to be releasably coupled to a pump station, and configured to receive saline from a saline source, receive contrast from a contrast source, and receive vacuum from a vacuum source, the cassette comprising:

a housing;

a saline subsystem supported by the housing, the saline subsystem having a first saline flow-path and one or more robotically actuated saline control valves arranged for directing saline through the first saline flow-path, the one or more robotically actuated saline control valves configured to operatively couple to one or more saline actuators located in the pump station such that each saline valve is coupled to a unique saline actuator when the cassette is coupled to the pump station,

a contrast subsystem supported by the housing, the contrast subsystem having a first contrast flow-path and one or more robotically actuated contrast control valves arranged for directing contrast through the first contrast flow-path, the one or more robotically actuated contrast control valves configured to operatively couple to one or more contrast actuators located in the pump station such that each contrast valve is coupled to a unique contrast actuator when the cassette is coupled to the pump station, and

a vacuum subsystem supported by the housing, the vacuum subsystem having a first vacuum flow-path and one or more robotically actuated vacuum control valves arranged for directing vacuum through the first vacuum flow-path, the one or more robotically actuated vacuum control valves configured to operatively couple to one or more vacuum actuators located in the pump station such that each vacuum valve is coupled to a unique vacuum actuator when the cassette is coupled to the pump station;

a splitter having a second saline flow-path, a second contrast flow-path, and a second vacuum flow-path, each of the second saline flow-path, second contrast flow-path, and second vacuum flow-path having a single proximal end and a plurality of distal ends;

a first tubing set having a first length and coupled to the cassette and the splitter, the first tubing set including:

a single saline channel coupled to the first saline flow-path and the proximal end of the second saline flow-path,

a single contrast channel coupled to the first contrast flow-path and the proximal end of the second contrast flow-path, and

a single vacuum channel coupled to the first vacuum flow-path and the proximal end of the second vacuum flow-path;

two or more hub assemblies, the two or more hub assemblies comprising a first hub assembly configured to have a third saline flow-path, a third contrast flow-path, and a third vacuum flow-path for providing saline, contrast, and vacuum to a lumen of a first catheter coupled to the first hub assembly; and

a second tubing set having a second length that is shorter than the first length, the second tubing set comprising a plurality of tube groups, a proximal end of each tube group of the plurality of tube groups coupled to the splitter and a distal end of each tube group of the plurality of tube groups coupled to one of the two or more hub assemblies, at least one of the plurality of tube groups including:

a saline subchannel coupled to the distal end of the second saline flow-path of the splitter,

a contrast subchannel coupled to the distal end of the second contrast flow-path of the splitter, and

a vacuum subchannel coupled to the distal end of the second vacuum flow-path of the splitter.

2. The fluidics system of claim 1 , wherein the first hub assembly comprises a mount, and wherein the mount comprises the third saline flow-path, the third contrast flow-path, and the third vacuum flow-path.

3. The fluidics system of claim 2 , wherein the mount further comprises a connector, wherein the mount is configured to provide saline, contrast, and vacuum through the connector to the lumen of the first catheter.

4. The fluidics system of claim 3 , wherein the first hub assembly comprises one or more robotically actuated control valves controlled by a control system to selectively align the third saline flow-path, the third contrast flow-path, and the third vacuum flow-path to be in fluid communication with the lumen of the first catheter via the connector.

5. The fluidics system of claim 1 , wherein the first length of the first tubing set is at least twice as long as the second length of the second tubing set.

6. The fluidics system of claim 1 , wherein a ratio of the first length to the second length is greater than 1:4.

7. The fluidics system of claim 1 , wherein the saline source comprises a first saline source, wherein the saline subsystem is configured to receive saline from the first saline source and a second saline source, wherein the one or more robotically actuated saline control valves includes a first robotically actuated valve controlled by a control system to place the first saline flow-path in fluid communication with the first saline source or the second saline source.

8. The fluidics system of claim 7 , wherein the control system controls the first robotically actuated valve to switch to receiving saline from a different one of the first and second saline sources based on receiving a signal from a sensor.

9. The fluidics system of claim 8 , wherein the sensor is a weight sensor configured to sense the weight of the first saline source and the second saline source.

10. The fluidics system of claim 8 , wherein the sensor is an air sensor configured to detect air in the first saline flow-path.

11. The fluidics system of claim 1 , wherein the contrast subsystem comprises a contrast pump actuatable by a control system to provide contrast to the first hub assembly.

12. The fluidics system of claim 1 , wherein the vacuum subsystem comprises a clot pod.

13. The fluidics system of claim 12 , wherein the clot pod includes at least one transparent surface positioned such that contents of the clot pod are visible from outside of the cassette.

14. The fluidics system of claim 1 , wherein the vacuum subsystem comprises a drip chamber in fluid communication with the first vacuum flow-path, wherein the one or more robotically actuated vacuum valves are configured to be controlled by a control system such that fluid aspirated by the vacuum subsystem is collected in the drip chamber.

15. The fluidics system of claim 14 , wherein the drip chamber includes at least one transparent surface positioned such that contents of the drip chamber are visible from outside of the cassette.

16. The fluidics system of claim 14 , wherein the vacuum subsystem further comprises a clot pod, and wherein the drip chamber is positioned in the first vacuum flow-path between the clot pod and the first tubing set.

17. The fluidics system of claim 14 , wherein the one or more robotically actuated vacuum valves are configured to be controlled by the control system for controlling the first vacuum flow-path through the drip chamber and a clot pod.

18. The fluidics system of claim 17 , wherein the one or more robotically actuated vacuum valves include a first valve positioned in the first vacuum flow-path between the drip chamber and the clot pod and a second valve positioned on an opposite side of the drip chamber in the first vacuum flow-path between the drip chamber and the first tubing set, wherein the first valve and the second valve are selectively controlled to control the flow of fluid and material from the two or more hub assemblies to the drip chamber and the clot pod.

19. The fluidics system of claim 1 , further comprising a plurality of catheters, wherein the plurality of catheters includes the first catheter and a second catheter, the second catheter connected to a second hub assembly of the two or more hub assemblies.

20. The fluidics system of claim 1 , wherein the first hub assembly includes a saline air sensor positioned to detect air in the third saline flow-path, and a contrast air sensor positioned to detect air in the third contrast flow-path.

21. The fluidics system of claim 20 , wherein the first hub assembly comprises one or more robotically actuated control valves controlled by a control system to selectively align the third saline flow-path and the third contrast flow-path of the first hub assembly to be in fluid communication with the lumen of the first catheter, and wherein the saline and contrast air sensors are positioned in the third saline and contrast flow-paths of the first hub assembly, respectively, between the one or more robotically actuated control valves and the second tubing set for detecting air in the third saline and contrast flow-paths before the air reaches the one or more robotically actuated control valves.

22. The fluidics system of claim 21 , wherein the first hub assembly further comprises a connector to provide saline, contrast, and vacuum through the connector to the lumen of the catheter, wherein one or more of the one or more robotically actuated control valves of the first hub assembly are controlled by a control system to block the saline and contrast flow-paths to the connector based on a signal from one of the saline and contrast air sensors.

23. The fluidics system of claim 1 , wherein each of the two or more hub assemblies includes a plurality of sensors, and wherein the first tubing set, the splitter, and each tube group of the second tubing set further comprises an electrical channel coupled to the plurality of sensors in the two or more hub assemblies, the electrical channel configured to communicate electrical signals from the plurality of sensors to an electrical interface on the cassette that is configured to electrically connect to a corresponding electrical interface on the pump station to provide the signals from the plurality of sensors in the hub assemblies to a control system.

24. The fluidics system of claim 23 , wherein the plurality of sensors includes a saline air sensor positioned to detect air in the third saline flow-path, a contrast air sensor positioned to detect air in the third contrast flow-path, and a pressure sensor.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 15, 2025
From: BARTHOLOMEW, KYLE; MUSTUFA, TABISH; CHHAYA, VEDANT
To: IMPERATIVE CARE, INC.
Reel/Frame 071132/0587 →
Continuity (4)
Provisional Application 63550926 · Feb 7, 2024
Provisional Application 63528038 · Jul 20, 2023
Provisional Application 63467251 · May 17, 2023
Related Publication 20240382668A1 · Nov 21, 2024
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