IP Library › Granted Patent US 12,379,382
Granted Patent B2
US 12,379,382 · App. 17/280,302 · Granted Aug 5, 2025

Analysis method, analytical method and microorganism identification method

Inventors: Miyuki Morozumi (Tokyo, JP); Megumi Sakuma (Tokyo, JP); Koretsugu Ogata (Kyoto, JP); Keisuke Shima (Kyoto, JP); Shinji Funatsu (Kyoto, JP)
Assignees: KEIO UNIVERSITY; SHIMADZU CORPORATION
G01N33/6848C12Q1/14
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Quick Facts
Patent No.
US 12,379,382
App. No.
17/280,302
Granted
Aug 5, 2025
Kind
B2
Abstract

An analysis method includes: acquiring data corresponding to a mass spectrum obtained by subjecting a sample containing a microorganism to mass spectrometry; and acquiring information on Group A Streptococcus of emm type 1, based on the presence or absence, or magnitude of a peak in a first range of m/z of 10930 or more to 10945 or less in the mass spectrum.

Claims (13)

1. An analysis method comprising:

generating data corresponding to a mass spectrum obtained by subjecting a sample containing a microorganism to mass spectrometry;

generating information on Group A Streptococcus of emm type 1, based on a presence or or magnitude of a peak in a first range of m/z of 10934 or more to 10945 or less in the mass spectrum; and

identifying whether or not the microorganism is Group A Streptococcus of emm type 1, based on the presence or magnitude of the peak in the first range.

2. The analysis method according to claim 1 , wherein

in the mass spectrometry, the sample is ionized by matrix-assisted laser desorption/ionization, using sinapic acid or CHCA as a matrix.

3. An analysis method comprising:

generating data corresponding to a mass spectrum obtained by subjecting a sample containing a microorganism to mass spectrometry;

generating information on Group A Streptococcus of emm type 12 based on a presence or absence, or magnitude of a peak in a second range of m/z of 6908 or more to 6918 or less in the mass spectrum;

and

identifying whether or not the microorganism is Group A Streptococcus of emm type 12, based on the presence or absence, or magnitude of a peak in the second range.

4. The analysis method according to claim 3 , wherein

in the mass spectrometry, the sample is ionized by matrix-assisted laser desorption/ionization, using sinapic acid or CHCA as a matrix.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 26, 2021
From: MOROZUMI, MIYUKI; SAKUMA, MEGUMI; OGATA, KORETSUGU; SHIMA, KEISUKE; FUNATSU, SHINJI
To: KEIO UNIVERSITY; SHIMADZU CORPORATION
Reel/Frame 055731/0090 →
Priority Claims (1)
JP 2018-185630 · Sep 28, 2018 · national
Continuity (1)
Related Publication 20220034900A1 · Feb 3, 2022
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