IP Library Granted Patent US 12,380,976
Granted Patent B2
US 12,380,976 · App. 18/439,707 · Granted Aug 5, 2025

Clinical laboratory-based disease management program, with automated patient-specific treatment advice

Inventors: Fredric L Coe (Chicago, IL); Brian J. Coe (Chicago, IL); John R. Asplin (Chicago, IL); Enno de Vries (Tower Lakes, IL); Elaine Worcester (Chicago, IL)
Assignee: Laboratory Corporation of America Holdings
G16H15/00G16H10/20G16H40/20G16H70/20G16H10/40G16H50/20
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Quick Facts
Patent No.
US 12,380,976
App. No.
18/439,707
Granted
Aug 5, 2025
Kind
B2
Abstract

A method is provided, the method including receiving a test result data, wherein said test result data represents a result of a test on a physical specimen, associating said test result data with a standard-of-care data, wherein said standard-of-care data represents a recommended course of action for the condition represented by the test result data, and transforming said specimen data and said standard-of-care data into a human-readable form. A system including a processor is provided, a software adapted to be executed on said processor, said software comprising instructions for receiving a test result data, wherein said test result data represents a result of a test on a physical specimen, associating said test result data with a standard-of-care data, wherein said standard-of-care data represents a recommended course of action for the condition represented by the test result data, and transforming said specimen data and said standard-of-care data into a human-readable form.

Claims (43)

1. A method for providing information related to test results, the method comprising:

receiving, by a processor executing software code, test result data;

querying, by the processor, standard-of-care data for the test result data using a matrix associated with medical information logic, wherein the medical information logic is extensible apart from compilation of the software code;

associating, by the processor, in response to the querying, the test result data with the standard-of-care data;

condensing, by the processor, using medical practice guideline data and the medical information logic, a medical treatment content tag for a specific patient condition;

accessing, by the processor, the medical treatment content tag for the specific patient condition and a recommended course of action corresponding to the test result data as determined at least in part by the medical treatment content tag;

building, by the processor, using an embedded language protocol, a patient-specific treatment recommendation using the medical treatment content tag and the recommended course of action; and

providing, by the processor, a report including the patient-specific treatment recommendation.

2. The method of claim 1 , wherein the report comprises a graphical representation of the test result data.

3. The method of claim 1 , wherein condensing the medical treatment content tag further comprises determining whether medication is being used.

4. The method of claim 1 , wherein the medical information logic comprises linked matrix trees to associate the test result data with standard-of-care data corresponding to the test result data.

5. The method of claim 4 , further comprising determining information regarding any change in the test result data from prior test results.

6. The method of claim 4 , wherein condensing the medical treatment content tag includes simultaneously interrogating grids of logic within the linked matrix trees for a plurality of diseases.

7. The method of claim 1 , wherein condensing the medical treatment content tag further comprises associating at least one of demographic data, medication data, or prior test results with standard-of-care data.

8. The method of claim 1 wherein the test result data is associated with at least one of chronic kidney disease, osteoporosis, or thyroid disease.

9. The method of claim 8 further comprising:

performing quality control on the test result data; and

evaluating the test result data in order to identify when at least a portion of the test result data fits into an acceptable range and when at least the portion of the test result data is above or below the acceptable range;

wherein the report includes information regarding the test result data compared to the acceptable range.

10. The method of claim 1 wherein the condensing the medical treatment content tag further comprises condensing the medical treatment content tag from narrative advice in a set of medical practice guidelines.

11. A system for providing information related to test results, comprising:

a processor configured to execute software code; and

a stored data structure communicatively coupled to the processor, the stored data structure defining medical information logic;

wherein, the processor is further configured to:

receive test result data;

query standard-of-care data for the test result data using a matrix associated with medical information logic, wherein the medical information logic is extensible apart from compilation of the software code;

associate the test result data with standard-of-care data using the medical information logic;

condense, using medical practice guideline data and the medical information logic, a medical treatment content tag for a specific patient condition;

access the medical treatment content tag for the specific patient condition and a recommended course of action corresponding to the test result data as determined at least in part by the medical treatment content tag;

build, using an embedded language protocol, a patient-specific treatment recommendation using the medical treatment content tag and the recommended course of action; and

provide a report including the patient-specific treatment recommendation.

12. The system of claim 11 , wherein the report comprises a graphical representation of the test result data.

13. The system of claim 11 , wherein the processor is further configured to determine whether medication is being used to associate the test result data with standard-of-care data to condense the medical treatment content tag.

14. The system of claim 11 , wherein the processor is further configured to determine whether the test result data has changed from prior test results.

15. The system of claim 14 , wherein the processor is further configured to determine information regarding any change in the test result data from prior test results.

16. The system of claim 11 , wherein the processor is further configured to associate at least one of demographic data, medication data, or prior test results with standard-of-care data to condense the medical treatment content tag.

17. The system of claim 11 , wherein the test result data are associated with at least one of chronic kidney disease, osteoporosis, or thyroid disease.

18. The system of claim 17 , wherein the processor is further configured to:

perform quality control on the test result data; and

evaluate the test result data in order to identify when at least a portion of the test result data fits into an acceptable range and when at least the portion of the test result data is above or below the acceptable range;

wherein the report includes information regarding the test result data compared to the acceptable range.

19. The system of claim 11 , wherein the stored data structure further comprises linked matrix trees to simultaneously interrogate grids of logic for a plurality of diseases.

20. The system of claim 11 , wherein the processor is further configured to condense the medical treatment content tag from narrative advice in a set of medical practice guidelines.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 1, 2025
From: COE, FREDRIC L.; COE, BRIAN J.; ASPLIN, JOHN R.; DE VRIES, ENNO; WORCESTER, ELAINE R.
To: LABORATORY CORPORATION OF AMERICA HOLDINGS
Reel/Frame 070694/0688 →
Continuity (6)
Continuation 17516928 · Nov 2, 2021
Continuation 16403915 · May 6, 2019
Continuation 13755361 · Jan 31, 2013
Continuation 12535287 · Aug 4, 2009
Provisional Application 61086023 · Aug 4, 2008
Related Publication 20240347155A1 · Oct 17, 2024
References Cited (42)
US 6208974B1 · Campbell et al. · 2001 [cited by applicant]
US 7306562B1 · Baykal · 2007 [cited by applicant]
US 7493264B1 · Kelly · 2009 [cited by examiner]
US 10290369B2 · Coe et al. · 2019 [cited by applicant]
US 11195603B2 · Coe et al. · 2021 [cited by applicant]
US 11901054B2 · Coe et al. · 2024 [cited by applicant]
US 20010013006A1 · Brown · 2001 [cited by applicant]
US 20030135393A1 · Burgess · 2003 [cited by applicant]
US 20040030586A1 · Cucchiara et al. · 2004 [cited by applicant]
US 20040034288A1 · Hennessy et al. · 2004 [cited by applicant]
US 20040078222A1 · Khan et al. · 2004 [cited by applicant]
US 20040103001A1 · Mazar et al. · 2004 [cited by applicant]
US 20050010444A1 · Iliff · 2005 [cited by applicant]
US 20050261558A1 · Eaton et al. · 2005 [cited by applicant]
US 20060064250A1 · Goldstein · 2006 [cited by applicant]
US 20070033075A1 · Hoffman et al. · 2007 [cited by applicant]
US 20070034213A1 · Poisner · 2007 [cited by applicant]
US 20070122824A1 · Tucker et al. · 2007 [cited by applicant]
US 20070168373A1 · Dettinger et al. · 2007 [cited by applicant]
US 20070192134A1 · Littenberg · 2007 [cited by examiner]
US 20080065422A1 · Weber · 2008 [cited by applicant]
US 20090119130A1 · Kimmel et al. · 2009 [cited by applicant]
US 20100076787A1 · Naylor et al. · 2010 [cited by applicant]
US 20100280395A1 · Lin · 2010 [cited by applicant]
US 20140039909A1 · Coe et al. · 2014 [cited by applicant]
U.S. Appl. No. 12/535,287, “Final Office Action”, dated Jul. 31, 2012, 12 pages. [cited by applicant]
U.S. Appl. No. 12/535,287, “Non-Final Office Action”, dated Nov. 29, 2011, 13 pages. [cited by applicant]
U.S. Appl. No. 13/755,361 , “Final Office Action”, Apr. 28, 2016, 25 pages. [cited by applicant]
U.S. Appl. No. 13/755,361, “Final Office Action”, dated Dec. 3, 2014, 17 pages. [cited by applicant]
U.S. Appl. No. 13/755,361, “Final Office Action”, dated Jun. 7, 2018, 16 pages. [cited by applicant]
U.S. Appl. No. 13/755,361, “Non Final Office Action”, dated Aug. 13, 2015, 19 pages. [cited by applicant]
U.S. Appl. No. 13/755,361, “Non-Final Office Action”, dated Aug. 11, 2017, 16 pages. [cited by applicant]
U.S. Appl. No. 13/755,361, “Non-Final Office Action”, dated Aug. 12, 2014, 11 pages. [cited by applicant]
U.S. Appl. No. 13/755,361 , “Notice of Allowance”, dated Dec. 18, 2018, 8 pages. [cited by applicant]
U.S. Appl. No. 16/403,915 , “Advisory Action”, dated Apr. 12, 2021, 5 pages. [cited by applicant]
U.S. Appl. No. 16/403,915, “Final Office Action”, dated Feb. 17, 2021, 16 pages. [cited by applicant]
U.S. Appl. No. 16/403,915, “Non-Final Office Action”, dated May 12, 2021, 8 pages. [cited by applicant]
U.S. Appl. No. 16/403,915, “Non-Final Office Action”, dated Oct. 6, 2020, 15 pages. [cited by applicant]
U.S. Appl. No. 16/403,915, “Notice of Allowance”, dated Aug. 5, 2021, 5 pages. [cited by applicant]
U.S. Appl. No. 17/516,928, “Non-Final Office Action”, dated Apr. 13, 2023, 15 pages. [cited by applicant]
U.S. Appl. No. 17/516,928, “Notice of Allowance”, dated Oct. 4, 2023, 11 pages. [cited by applicant]
PCT/US09/52692, “International Search Report and Written Opinion”, dated Sep. 24, 2009, 9 pages. [cited by applicant]