IP Library › Granted Patent US 12,383,713
Granted Patent B2
US 12,383,713 · App. 16/824,823 · Granted Aug 12, 2025

Devices and methods for alleviating lymphatic system congestion

Inventors: Maxim Itkin (Bala Cynwyd, PA); Yoav Dori (Wynnewood, PA)
Assignees: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; THE CHILDREN'S HOSPITAL OF PHILADELPHIA
A61M27/002A61M39/24A61M2202/0405A61M2205/50
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Quick Facts
Patent No.
US 12,383,713
App. No.
16/824,823
Granted
Aug 12, 2025
Kind
B2
Abstract

The presently disclosed subject matter relates to methods and devices for decompressing the lymphatic system. In particular, the present disclosure provides devices for actively or passively decompressing the lymphatic system and methods of their use and deployment within a subject. In certain non-limiting embodiments, a device of the present disclosure can include a pump for actively transferring lymph fluid from the lymphatic fluid into the venous system.

Claims (13)

1. A device for reducing the congestion of the lymphatic system comprising:

a. an inlet tubular member;

b. a pump coupled to the inlet tubular member;

c. an outlet tubular member coupled to the pump;

d. a covered stent directly connected to the outlet tubular member;

e. a valve coupled to the covered stent,

wherein the inlet tubular member is configured to transfer lymph fluid from the lymphatic system through the outlet tubular member, and wherein the valve is configured to prevent reflux of blood from the venous system into the thoracic duct; and

f. a controller directly connected to the pump.

2. The device of claim 1 , wherein the covered stent is a self-expanding stent.

3. The device of claim 1 , wherein the covered stent is comprised of a polymer-based coating.

4. The device of claim 1 further comprising:

a. a sensor coupled to the controller,

wherein an increase in pressure detected by the sensor results in the activation of the pump by the controller to transfer lymph fluid from the lymphatic system.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 1, 2020
From: DORI, YOAV
To: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
Reel/Frame 052797/0106 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 1, 2020
From: ITKIN, MAXIM
To: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Reel/Frame 052797/0140 →
Continuity (3)
Division 15321284
Provisional Application 62017613 · Jun 26, 2014
Related Publication 20200215313A1 · Jul 9, 2020
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