IP Library › Granted Patent US 12,387,852
Granted Patent B2
US 12,387,852 · App. 18/785,860 · Granted Aug 12, 2025

Apparatus and method for generating clinical decision support

Inventors: Leon Ptaszek (Milton, MA); Rohit Jain (Danville, CA); Anand Ramani (Fresno, CA); Animesh Agarwal (San Mateo, CA); Yogisha Heggadahalli Jayendra (Bengaluru, IN); Sanjeev Shrinivas Nadapurohit (Bengaluru, IN); Karthik K. Bharadwaj (Bengaluru, IN); Shashi Kant (Bengaluru, IN); Shiva Verma (Bangalore, IN)
Assignee: Anumana, Inc.
G16H70/20G16H20/40G16H50/30
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Quick Facts
Patent No.
US 12,387,852
App. No.
18/785,860
Granted
Aug 12, 2025
Kind
B2
Abstract

An apparatus and method for generating clinical decision support is disclosed. The apparatus includes at least a processor and a computer-readable storage medium communicatively connected to the at least a processor, wherein the computer-readable storage medium contains instructions configuring the at least processor to receive user data, generate a fused feature vector correlating the user data to a plurality of clinical outcomes by training a plurality of deep neural networks (DNNs) to output a first set of feature vectors, a second set of feature vectors and a third set of feature vectors, fusing the first, second, and third set of features vectors to form the fused feature vector, generate a procedural output using the fused feature vector, and display the procedural output through a user interface.

Claims (43)

1. An apparatus for generating clinical decision support, wherein

the apparatus comprises:

at least a processor;

a computer-readable storage medium communicatively connected to the at least a processor, wherein the computer-readable storage medium contains instructions configuring the at least processor to:

receive user data associated with a subject, the user data comprising:

electrocardiogram (ECG) data comprising a plurality of signals representative of an electrical activity of a heart of the subject;

image data comprising a plurality of images associated with the heart of the subject; and

user historical data comprising a plurality of records;

generating, using a first deep neural network (DNN), a first set of feature vectors representative of the ECG data;

generating, using a second DNN, a second set of feature vectors representative of the image data;

generating, using a third DNN, a third set of feature vectors representative of the user historical data; and

generate a set of dimensionally reduced feature vectors for each of the first set, the second set, and the third set of feature vectors; fusing the first, second, and third set of dimensionally reduced features vectors to form the fused feature vector;

generate a procedural output using the fused feature vector; and

display the procedural output through a user interface.

2. The apparatus of claim 1 , wherein the first DNN is trained with time series data of exemplary user data correlated to clinical outcomes to output the first set of feature vectors.

3. The apparatus of claim 1 , wherein the second DNN is trained with image data of exemplary user data correlated to clinical outcomes to output the second set of feature vectors.

4. The apparatus of claim 1 , wherein the third DNN is trained with natural language data of exemplary user data correlated to clinical outcomes to output the third set of feature vectors.

5. The apparatus of claim 1 , wherein the procedural output comprises a pre-procedure output, a during-procedure output, and a post-procedure output.

6. The apparatus of claim 5 , wherein the pre-procedure output comprises an ablation strategy outlining focus on key aspects of cardiac ablation prior to an ablation procedure.

7. The apparatus of claim 5 , wherein the during-procedure output comprises an integrative assessment data assessing lesion quality and contiguity implemented in an intraprocedural visualization stage of an ablation procedure.

8. The apparatus of claim 5 , wherein the post-procedure output comprises a post-ablation summative assessment of durability of ablation estimating a likelihood of atrial fibrillation recurrence after an ablation procedure.

9. The apparatus of claim 1 , wherein generating the procedural output comprises training a fused feature classifier based on the fused feature vector to output a pre-procedure output and a post-procedure output.

10. The apparatus of claim 1 , wherein generating the procedural output comprises training a fused object detection model based on the fused feature vector to output a during-procedure output.

11. A method for generating clinical decision support, wherein the method comprises:

receiving, by a computing device, user data associated with a subject, the user data comprising:

electrocardiogram (ECG) data comprising a plurality of signals representative of an electrical activity of a heart of the subject;

image data comprising a plurality of images associated with the heart of the subject; and

user historical data comprising a plurality of records;

generating, using a first deep neural network (DNN), a first set of feature vectors representative of the ECG data;

generating, using a second DNN, a second set of feature vectors representative of the image data;

generating, using a third DNN, a third set of feature vectors representative of the user historical data; and

generate a set of dimensionally reduced feature vectors for each of the first set, the second set, and the third set of feature vectors; fusing the first, second, and third set of dimensionally reduced features vectors to form the fused feature vector;

generating, by the computing device, a procedural output using the fused feature vector; and

displaying, by the computing device, the procedural output through a user interface.

12. The method of claim 11 , wherein the first DNN is trained with time series data of exemplary user data correlated to clinical outcomes to output the first set of feature vectors.

13. The method of claim 11 , wherein the second DNN is trained with image data of exemplary user data correlated to clinical outcomes to output the second set of feature vectors.

14. The method of claim 11 , wherein the third DNN is trained with natural language data of exemplary user data correlated to clinical outcomes to output the third set of feature vectors.

15. The method of claim 11 , wherein the procedural output comprises a pre-procedure output, a during-procedure output, and a post-procedure output.

16. The method of claim 15 , wherein the pre-procedure output comprises an ablation strategy outlining focus on key aspects of cardiac ablation prior to an ablation procedure.

17. The method of claim 15 , wherein the during-procedure output comprises an integrative assessment data assessing lesion quality and contiguity implemented in an intraprocedural visualization stage of an ablation procedure.

18. The method of claim 15 , wherein the post-procedure output comprises a post-ablation summative assessment of durability of ablation estimating a likelihood of atrial fibrillation recurrence after an ablation procedure.

19. The method of claim 11 , wherein generating the procedural output comprises training a fused feature classifier based on the fused feature vector to output a pre-procedure output and a post-procedure output.

20. The method of claim 11 , wherein generating the procedural output comprises training a fused object detection model based on the fused feature vector to output a during-procedure output.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2024
From: PTASZEK, LEON; JAIN, ROHIT; RAMANI, ANAND; AGARWAL, ANIMESH; JAYENDRA, YOGISHA HEGGADAHALLI; NADAPUROHIT, SANJEEV SHRINIVAS; BHARADWAJ, KARTHIK K.; KANT, SHASHI; VERMA, SHIVA
To: ANUMANA, INC.
Reel/Frame 068285/0597 →
Continuity (2)
Provisional Application 63614858 · Dec 26, 2023
Related Publication 20250210206A1 · Jun 26, 2025
References Cited (10)
US 20080154132A1 · Hall · 2008 [cited by examiner]
US 20130282005A1 · Koch · 2013 [cited by examiner]
US 20140022250A1 · Mansi · 2014 [cited by examiner]
US 20150366500A1 · Aoyagi · 2015 [cited by examiner]
CN 116646013A · 2023 [cited by applicant]
CN 116646078A · 2023 [cited by applicant]
WO WO2022060948A1 · 2022 [cited by examiner]
WO 2022079623A1 · 2022 [cited by applicant]
S. Bozyel et al; Artificial Intelligence-Based Clinical Decision Support Systems in Cardiovascular Diseases; “The Anatolian Journal Of CardiologyAvailable Online Date: Jan. 1, 2024”. [cited by applicant]
S. Tang et al; Machine Learning-Enabled Multimodal Fusion of Intra-Atrial and Body Surface Signals in Prediction of Atrial Fibrillation Ablation Outcomes; Circ Arrhythm Electrophysiol. Aug. 2022; 15(8). [cited by applicant]