Leave-on oral care compositions
Leave-on oral care compositions including a hyaluronic acid or a salt thereof good spreadability and improved retention period are provided for promoting Gum Health of a user. Kits and methods are also provided.
1. A leave-on oral care composition comprising:
from about 0.1% to about 5.0%, by weight of the composition, of a hyaluronic acid or a salt thereof,
wherein the composition has a Viscosity Consistency Coefficient K of from about 50 Pa·s to about 250 Pa·s as measured at 22°° C. at a shear rate range of 0.1-10s- −1 , and
wherein the oral care composition has a Mucoadhesion Index of no less than about 0.6 Fluorescent Intensity Percentage (“FI%”).
2. The leave-on oral care composition of claim 1 , wherein the Viscosity Consistency Coefficient K is from about 50 Pa·s to about 200 Pa·s.
3. The leave-on oral care composition of claim 1 , wherein the Mucoadhesion Index is no less than about 0.8 FI %.
4. The leave-on oral care composition of claim 1 , wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 5,000,000 Daltons.
5. The leave-on oral care composition of claim 1 , further comprising from about 0.1% to about 10%, by weight of the composition, of a polyacrylic acid.
6. The leave-on oral care composition of claim 1 , further comprising an additional polymer, wherein the additional polymer is selected from the group consisting of xanthan gum, carrageenan, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, polyvinyl pyrrolidine, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, and combinations thereof.
7. The leave-on oral care composition of claim 6 , wherein the additional polymer is present in an amount of from about 0.1% to about 10%, by weight of the composition.
8. The leave-on oral care composition of claim 1 , wherein a total water content is from about 30% to about 85%, by weight of the composition.
9. The leave-on oral care composition of claim 1 , wherein the oral care composition is substantially free of abrasives.
10. The leave-on oral care composition of claim 1 , further comprising a vitamin, wherein the vitamin is selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.
11. A kit comprising a toothpaste and the leave-on oral care composition of claim 1 .
12. A kit comprising the leave-on oral care composition of claim 1 and a delivery carrier.
13. The kit of claim 12 , wherein the delivery carrier comprises a strip, a film of material, a dental tray, an aligner, a sponge material, an applicator, or mixtures thereof.
14. A method of improving gum health of a subject, the method comprising the steps of applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue without removal for a duration of time from about 1 minute to about 1000 minutes.
15. The method of claim 14 , wherein the applying step is the last step of an oral hygiene regimen.
16. The method of claim 14 , wherein the oral care composition is applied to intraoral tissue with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.
17. A method of improving gum health of a subject, the method comprising:
(a) brushing teeth of the subject with an antibacterial toothpaste; and
(b) subsequently, applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue without removal for a duration of time of at least about 2 minutes.
18. The method of claim 17 , wherein the oral care composition is applied to intraoral tissue with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.
19. The leave-on oral care composition of claim 1 , wherein the Viscosity Consistency Coefficient K is from about 50 Pa·s to about 100 Pa·s, and the Mucoadhesion Index is less than about 20 FI %.