IP Library › Granted Patent US 12,419,529
Granted Patent B2
US 12,419,529 · App. 17/353,194 · Granted Sep 23, 2025

Noninvasive blood pressure monitoring system and method

Inventor: Rene Coffeng (Helsinki, FI)
Assignee: GE Precision Healthcare LLC
A61B5/02255A61B5/0205A61B5/02405A61B5/025A61B5/0531A61B5/352A61B2562/0247
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Quick Facts
Patent No.
US 12,419,529
App. No.
17/353,194
Granted
Sep 23, 2025
Kind
B2
Abstract

A method of measuring noninvasive blood pressure includes determining a window for pulse detection for a patient, receiving a pressure signal measured from a measure sensor in a blood pressure cuff, and setting a pulse detection period for each heart beat based on the window and a heart beat indicator indicating at least one heart beat time for the patient. The pressure signal is then examined within each pulse detection period to identify a pressure peak therein. A blood pressure for the patient is determined based on the pressure peaks detected in the pressure signal.

Claims (58)

1. A method of measuring non-invasive blood pressure, the method comprising:

determining, at a controller, a window for pulse detection for a patient;

receiving, at the controller, a pressure signal measured from a pressure sensor in a blood pressure cuff;

setting, with the controller, a pulse detection period for each heart beat based on the window, a heart beat indicator indicating at least one heart beat time, and an RR interval variability;

examining, at the controller, the pressure signal within each pulse detection period to identify a pressure peak therein;

controlling, with the controller, a pressure of the blood pressure cuff to maintain each of a series of cuff pressures until at least two pressure peaks are identified having an amplitude within a threshold amplitude range within each of the series of cuff pressures; and

determining, at the controller, a blood pressure for the patient based on the pressure peaks.

2. The method of claim 1 , further comprising:

calculating the window for pulse detection based on an average heart rate and/or the RR interval variability for the patient; and

determining the heart beat indicator based on at least one of an ECG waveform for the patient, photoplethysmogram waveform for the patient, or a chest impedance waveform for the patient.

3. The method of claim 2 , wherein the heart beat indicator is determined based on detected R-peaks in the ECG waveform for the patient.

4. The method of claim 1 , further comprising determining the threshold amplitude range based on an amplitude of at least one previous pressure peak for the patient.

5. The method of claim 1 , further comprising:

calculating a time out maximum period based on an average heart rate and/or the RR interval variability; and

controlling the pressure of the blood pressure cuff to maintain each of the series of cuff pressures until either the at least two pressure peaks within the threshold amplitude range are identified or the time out maximum period has expired.

6. A method of measuring non-invasive blood pressure using a blood pressure cuff, the method comprising:

receiving an average heart rate and an RR interval variability for a patient;

calculating a window for pulse detection based on the average heart rate and the RR interval variability;

receiving a pressure signal measured from a pressure sensor in the blood pressure cuff;

receiving a heart beat indicator indicating heart beat times for the patient;

deflating the blood pressure cuff in a series of pressure steps and at each pressure step:

(a) setting a first pulse detection period based on the window and a first heart beat time indicated by the heart beat indicator;

(b) detecting a first pressure peak in the pressure signal within the first pulse detection period;

(c) setting a second pulse detection period based on the window and a second heart beat time indicated by the heart beat indicator;

(d) detecting a second pressure peak in the pressure signal within the second pulse detection period;

(e) continuing to set pulse detection periods and detect pressure peaks until at least two pressure peaks are detected having an amplitude within a threshold amplitude range prior to a time out maximum period;

(f) controlling deflation of the cuff to a next pressure step in the series of pressure steps; and

determining a blood pressure for the patient based on the at least two pressure peaks at each pressure step.

7. The method of claim 6 , wherein when the at least two pressure peaks having the amplitude within the threshold amplitude range are not detected prior to the time out maximum period at any one or more pressure steps in the series of pressure steps, then adjusting the threshold amplitude range and reperforming steps (a) through (f) using the pressure signal and the heart beat indicator recorded during the series of pressure steps and then redetermining the blood pressure for the patient based on the at least two pressure peaks at each pressure step.

8. The method of claim 6 , wherein when the at least two pressure peaks having the amplitude within the threshold amplitude range are not detected prior to the time out maximum period at any one or more pressure steps in the series of pressure steps, then adjusting the window and reperforming steps (a) through (f) using the pressure signal and the heart beat indicator recorded during the series of pressure steps and then redetermining the blood pressure for the patient based on the at least two pressure peaks at each pressure step.

9. The method of claim 6 , wherein when the at least two pressure peaks having the amplitude within the threshold amplitude range are not detected prior to the time out maximum period at any one or more pressure steps in the series of pressure steps, then adjusting the threshold amplitude range and adjusting the window and reperforming steps (a) through (e) using the pressure signal and the heart beat indicator recorded during the series of pressure steps and then redetermining the blood pressure for the patient based on the at least two pressure peaks at each pressure step.

10. The method of claim 6 , wherein when the at least two pressure peaks having the amplitude within the threshold amplitude range are not detected prior to the time out maximum period at any one or more pressure steps in the series of pressure steps, then:

reinflating the blood pressure cuff;

deflating the blood pressure cuff in the series of pressure steps and at each pressure step performing steps (a) through (f).

11. The method of claim 6 , further comprising calculating the time out maximum period based on the average heart rate and the RR interval variability.

12. The method of claim 6 , further comprising determining the threshold amplitude range based on an amplitude of at least one previous pressure peak for the patient.

13. The method of claim 6 , further comprising determining the heart beat indicator based on at least one of an ECG waveform for the patient, photoplethysmogram waveform for the patient, or a chest impedance waveform for the patient.

14. A non-invasive blood pressure measurement system comprising:

a blood pressure cuff comprising a pressure sensor configured to measure a pressure signal from a patient;

a controller configured to:

receive an RR interval variability for a patient;

calculate a window for pulse detection based on the RR interval variability;

set a pulse detection period for each heart beat based on the window and a heart beat indicator indicating at least one heart beat time;

examine the pressure signal to identify a pressure peak within each pulse detection period;

controlling a pressure of the blood pressure cuff to maintain each of a series of cuff pressures until at least two pressure peaks are identified having an amplitude within a threshold amplitude range within each of the series of cuff pressures; and

determine a blood pressure for the patient based on the pressure peaks.

15. The system of claim 14 , wherein the controller is further configured to control deflation of the pressure cuff in a series of pressure steps based on the pressure peaks.

16. The system of claim 15 , wherein the controller is further configured to:

calculate a time out maximum period based on an average heart rate for the patient and the RR interval variability; and

control the deflation of the blood pressure cuff to maintain each of the series of cuff pressures until either the at least two pressure peaks within the threshold amplitude range are identified or the time out maximum period has expired.

17. The system of claim 14 , wherein the heart beat indicator is determined based on detected R-peaks in an ECG waveform for the patient.

18. The system of claim 14 , wherein the controller is further configured to:

determine the threshold amplitude range based on an amplitude of at least one previous pressure peak for

the patient.

19. The system of claim 18 , wherein the controller is further configured to:

determine whether the at least two pressure peaks are detected having the amplitude within the threshold amplitude range prior to a time out maximum period;

if the at least two pressure peaks having the amplitude within the threshold amplitude range are not detected prior to the time out maximum period at any one or more pressure steps in a series of pressure steps, then adjust the threshold amplitude range and/or adjust the window and re-examine the pressure signal within each of the pulse detection periods to identify a new pressure peak within each pulse detection period and determine the blood pressure for the patient based on the new pressure peaks; and

if the at least two pressure peaks having the amplitude within the threshold amplitude range are detected prior to the time out maximum period at any one or more pressure steps in a series of pressure steps, then determine the blood pressure for the patient based on the at least two pressure peaks.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2022
From: COFFENG, RENE
To: GE PRECISION HEALTHCARE LLC
Reel/Frame 059045/0878 →
Continuity (1)
Related Publication 20220400967A1 · Dec 22, 2022
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