IP Library Granted Patent US 12,419,929
Granted Patent B2
US 12,419,929 · App. 18/659,701 · Granted Sep 23, 2025

Compositions of herbal formulations and uses thereof

Inventors: Tomy Yesudas (Kollam Kerala, IN); Philip Alex (Abingdon, MD); Michael Centola (Oklahoma City, OK); Adam Joshua Payne (Edmond, OK)
Assignee: Haus Bioceuticals, Inc.
A61K36/90A61K36/185A61K36/22A61K36/23A61K36/24A61K36/27A61K36/28A61K36/29A61K36/31A61K36/35A61K36/48A61K36/66A61K36/68A61K36/71A61K36/76A61K36/77A61K36/808A61K36/899
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,419,929
App. No.
18/659,701
Granted
Sep 23, 2025
Kind
B2
Abstract

Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive pharmaceutical ingredient, and/or a pharmaceutically acceptable excipient.

Claims (16)

1. A method of reducing symptoms associated with a skin condition in a subject, wherein the skin condition is associated with acne vulgaris, psoriasis, eczema, atopic dermatitis, pruritis, erythema, or excoriations, the method comprising the steps of:

identifying the subject in need thereof; and

applying an effective amount of a topical composition to a skin of the subject, wherein the topical composition is in the form of a cream, gel, lotion, ointment, or salve for application to the skin of the subject, and wherein the topical composition comprises:

a mixture of at least seven different plant extracts, wherein each of the at least seven plant extracts is selected from the group consisting of Achillea millefolium; Aesculus hippocastanum; Althaea officinalis; Avena sativa; Berberis vulgaris; Capsella bursa - pastoris; Cochlearia officinalis; Conium maculatum; Ervum lens; Hamamelis virginiana; Hydrastis canadensis; Malva sylvestris; Matricaria chamomilla; Nasturtium officinale; Phytolacca decandra; Pimpinella saxifraga; Populus alba; Populus tremuloides; Rhus toxicodendron; Sambucus nigra; Sanguinaria canadensis; Scrophularia nodosa; Smilax medica; Tussilago farfara; Veronica officinalis; Vincetoxicum officinale ; and combinations thereof; and wherein each of the at least seven different plant extracts is extracted in an extraction composition that comprises at least one solvent other than water, and wherein each of the at least seven different plant extracts is extracted by a process selected from the group consisting of steam distillation, oil separation, fermentation, hygroscopic salt extraction, and cohobation; and

at least one pharmaceutically acceptable carrier, diluent, or excipient.

2. The method of claim 1 , wherein the mixture of the topical composition comprises at least eight different plant extracts.

3. The method of claim 1 , wherein the mixture of the topical composition comprises at least ten different plant extracts.

4. The method of claim 1 , wherein the mixture of the topical composition comprises at least twelve different plant extracts.

5. The method of claim 1 , wherein the mixture of the topical composition comprises at least fourteen different plant extracts.

6. The method of claim 1 , wherein the mixture of the topical composition comprises at least sixteen different plant extracts.

7. The method of claim 1 , wherein the mixture of the topical composition comprises at least eighteen different plant extracts.

8. The method of claim 1 , wherein the mixture comprises plant extracts obtained from Achillea millefolium; Aesculus hippocastanum; Althaea officinalis; Avena sativa; Berberis vulgaris; Capsella Bursa Pastoris; Cochlearia officinalis; Ervum lens; Hamamelis virginiana; Malva sylvestris; Matricaria chamomilla; Nasturtium officinale; Phytolacca decandra; Pimpinella saxifraga; Populas alba; Populus tremuloides; Sambucus nigra; Sanguinaria Canadensis; Scrophularia nodosa; Smilax medica; Tussilago farfara; Veronica officinalis ; and Vincetoxicum officinale.

9. The method of claim 1 , wherein the at least one solvent present in the extraction composition utilized with at least one of the plant extracts is selected from the group consisting of an alcohol, a polyhydric alcohol, an ether, an ester, a carboxylic acid, an amide, a carbonate, supercritical fluid carbon dioxide, an ionic liquid, an alkane, a petroleum-derived oil, a plant oil, and combinations thereof.

10. The method of claim 9 , wherein the at least one solvent comprises ethanol.

11. The method of claim 1 , wherein the extraction composition further comprises water.

12. The method of claim 1 , wherein the topical composition is formulated as a sustained release dosage form.

Continuity (7)
Continuation 17684811 · Mar 2, 2022
Continuation 16842528 · Apr 7, 2020
Continuation 15889921 · Feb 6, 2018
Continuation 14733771 · Jun 8, 2015
Continuation 13471913 · May 15, 2012
Provisional Application 61486724 · May 16, 2011
Related Publication 20240285721A1 · Aug 29, 2024
References Cited (1)
JP 2002047132A · 2002 [cited by examiner]