IP Library › Granted Patent US 12,427,524
Granted Patent B2
US 12,427,524 · App. 17/626,178 · Granted Sep 30, 2025

Reagent storage container comprising a sampling passage with improved sealing

Inventors: Nikhil Vazirani (Maharashtra, IN); Valentin Ghoris (Montpellier, FR); Martin Hackl (Graz, AT); Stephan Köstler (Kainbach, AT); Petra Theisl (Tillmitsch, AT)
Assignee: ERBA DIAGNOSTICS LIMITED
B01L3/523B01L2200/0689B01L2200/16B01L2300/04B01L2300/123B01L2300/168
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Quick Facts
Patent No.
US 12,427,524
App. No.
17/626,178
Granted
Sep 30, 2025
Kind
B2
Abstract

The present invention relates to a container for storing a reagent, the container comprising: a storage space for reagent (R) comprising a flexible pouch; a passage having a first end ( 4 ) that opens onto the outside of the container and a second end that opens into the storage space, the passage being designed to allow a sampling device ( 20 ) to access the storage space; a deformable partition ( 7 ) that closes off the passage when said partition is not mechanically loaded and which can be loaded by the sampling device to a position in which the passage is open; a seal ( 6 ) that is positioned in the passage and comprises an elastically deformable rim ( 64 ) defining an orifice ( 61 ) that is designed to receive part of the sampling device ( 20 ), said rim ( 64 ) being designed to establish a seal together with the outer walls of the sampling device when said device is introduced into the passage.

Claims (30)

1. An assembly for storing and sampling a reagent, comprising:

a container for storing a reagent, the container comprising:

a reagent storage space, said reagent storage space comprising a flexible bag,

a passage having a first end opening out outside the container and a second end opening out in the reagent storage space,

a chimney traversed by the passage, said chimney extending inside the reagent storage space between an upper part and a lower end, the upper part of the chimney being secured to the reagent storage space,

a sampling device configured to be inserted at least partly into the passage the first end to access the reagent storage space,

the container further comprising:

a deformable partition having a closed position wherein the deformable partition closes off the passage when said partition is not mechanically stressed, and which is able to be stressed by the sampling device towards an open position wherein the passage is open, wherein the deformable partition returns to the closed position when the deformable partition is no longer mechanically stressed,

a seal disposed in the passage, said seal comprising an elastically deformable rim defining an orifice adapted to receive part of the sampling device, said elastically deformable rim being adapted to

pass from a relaxed state to a deformed state when the sampling device is inserted in the orifice,

adhere to outer walls of the sampling device to seal the orifice when the sampling device is in the orifice,

pass from the deformed state to the relaxed state when the sampling device is withdrawn from the orifice,

wherein the seal and the deformable partition are positioned on the lower end of the chimney.

2. The assembly according to claim 1 , wherein the elastically deformable rim is configured so that the orifice is circular and has a diameter of between 0.5 millimeters and 5 millimeters, in the absence of a sampling device in the passage.

3. The assembly according to claim 1 , wherein the elastically deformable rim is configured to pass from the deformed state to the relaxed state by tilting towards the reagent storage space upon insertion of the sampling device.

4. The assembly according to claim 1 , wherein the seal includes a truncated cone body ending with the elastically deformable rim.

5. The assembly according to claim 1 , wherein the seal comprises an outer annular edge and further comprises an inner portion located radially between the outer annular edge and the elastically deformable rim,

a thickness of the inner portion tapering from the outer annular edge until reaching a minimum thickness at the elastically deformable rim.

6. The assembly according to claim 1 , wherein the deformable partition comprises a pre-slit membrane including a slot.

7. The assembly according to claim 1 , wherein the seal comprises an outer annular edge and further comprises an inner portion located radially between the outer annular edge and the elastically deformable rim,

a thickness of the inner portion tapering from the outer annular edge until reaching a minimum thickness at the elastically deformable rim,

and wherein the outer annular edge is fixed to the chimney.

8. The assembly according to claim 1 , wherein the chimney ends comprises an enlarged head for closing the container, the upper part of the chimney being secured to the reagent storage space at the enlarged head.

9. The assembly according to claim 8 , wherein the enlarged head includes a plurality of ridges on which the flexible bag is welded.

10. The assembly according to claim 1 , wherein the chimney comprises a cap inside which an inner cavity extends, the deformable partition and the seal being disposed in the inner cavity and fixed on the lower end of the chimney by the cap.

11. The assembly according to claim 10 , wherein the deformable partition has an outer annular partition edge and wherein the cap has a shoulder at an internal edge of the inner cavity, the shoulder being complementary with the outer annular partition edge.

12. The assembly according to claim 1 , wherein the container has an external surface which is at least partly covered with a film comprising a material adapted to filter electromagnetic radiation harmful to the liquid reagent and/or adapted to reduce the porosity of the surface external to gases.

13. The assembly according to claim 12 , wherein said material is aluminum.

14. The assembly according to claim 1 , wherein the flexible bag comprises a bottom wall, the bottom wall being conical.

15. The assembly according to claim 1 , wherein the elastically deformable rim is configured so that the orifice has, at rest, a surface strictly smaller than a sectional surface of the sampling device.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2022
From: VAZIRANI, NIKHIL; GHORIS, VALENTIN; HACKL, MARTIN; KÖSTLER, STEPHAN; THEISL, PETRA
To: ERBA DIAGNOSTICS LIMITED
Reel/Frame 060809/0038 →
Priority Claims (1)
FR 1908044 · Jul 17, 2019 · national
Continuity (1)
Related Publication 20220274114A1 · Sep 1, 2022
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