IP Library Granted Patent US 12,433,548
Granted Patent B2
US 12,433,548 · App. 17/907,923 · Granted Oct 7, 2025

Medical image processing device, computer program, and nuclear medicine device

Inventors: Hideaki Tashima (Chiba, JP); Taiga Yamaya (Chiba, JP)
Assignee: NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
A61B6/037A61B6/4258G01N23/20066G06T7/0012G06T11/003G06T2207/10104
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,433,548
App. No.
17/907,923
Granted
Oct 7, 2025
Kind
B2
Abstract

An image is reconstituted by iterative approximation, a PET event updated image is produced by updating a current image using a PET event, a Compton event updated image is produced by updating the current image using a Compton event, the PET event updated image and the Compton event updated image that have been independently produced are weighted and added together, and the current image is updated using an image obtained by addition processing. In this way, PET events and Compton events, which have different properties, can be used in combination to efficiently and stably reconstitute images, improving image quality.

Claims (24)

1. A medical image processing device for reconstructing an image by iterative approximation using a PET event where a coincidence signal of a pair of annihilation radiations is obtained and a Compton event is obtained by Compton scattering, the medical image processing device comprising:

a computer configured to perform a set of functions, comprising:

produce a PET event updated image by updating a current image using a PET event;

produce a Compton event updated image by updating the current image using a Compton event;

weight and add the PET event updated image and the Compton event updated image produced independently of each other;

update the current image using an image obtained by the weighting and adding of the PET event updated image and the Compton event updated image; and

iterate processing of the PET event updated image, the Compton event updated image, the weighting and adding of the PET event updated image and the Compton event updated image, and the updating of the current image using the image obtained by the weighting and adding of the PET event updated image and the Compton event updated image.

2. The medical image processing device according to claim 1 , wherein the computer is further configured to set a number of subsets as an update parameter for either the production of the PET event updated image or the production of the Compton even updated image.

3. The medical image processing device according to claim 2 , wherein the computer is configured to make a sub iteration of image update using the subsets for either the production of the PET event updated image or the production of the Compton event updated image.

4. The medical image processing device according to claim 2 , wherein the number of subsets that is the update parameter, a number of times of sub iterations, and timing of weighted addition can be set for the PET event and the Compton event independently.

5. The medical image processing device according to claim 1 , wherein the Compton event includes an annihilation radiation Compton event and a single gamma-ray Compton event.

6. A nuclear medicine device comprising:

a PET-Compton simultaneous measurement device including scatterer detectors and absorber detectors; and

the medical image processing device according to claim 5 .

7. The nuclear medicine device according to claim 6 , wherein at least either the scatterer detectors or the absorber detectors are arranged in a ring shape, a partial ring shape, or an opposed shape.

8. The nuclear medicine device according to claim 6 , wherein the scatterer detectors are arranged in a multi-ring shape.

9. The nuclear medicine device according to claim 6 , wherein the scatterer detectors are located inside a measurement field of view of the absorber detectors.

10. The nuclear medicine device according to claim 6 , wherein the scatterer detectors are located outside a measurement field of view of the absorber detectors.

11. The nuclear medicine device according to claim 6 , wherein a measurement field of view of the Compton event is made greater than a measurement field of view of the PET event.

12. The nuclear medicine device according to claim 11 , wherein a pixel size of the measurement field of view of the Compton event is made greater than that of the measurement field of view including the PET event.

13. The medical image processing device according to claim 1 , wherein the PET event includes a PET event between absorber detectors, a PET event between a scatterer detector and an absorber detector, and a PET event between scatterer detectors.

14. The medical image processing device according to claim 1 , wherein the PET event includes a PET event with time of flight information and a PET event without time of flight information.

15. The medical image processing device according to claim 1 , wherein, if a nuclide is a 3-gamma-ray nuclide, a 3-gamma event is further included.

16. A non-transitory computer readable recording medium for recording a computer program for causing the computer to implement the set of functions of the medical image processing device according to claim 1 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2022
From: TASHIMA, HIDEAKI; YAMAYA, TAIGA
To: NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
Reel/Frame 060931/0656 →
Priority Claims (1)
JP 2020-044795 · Mar 13, 2020 · national
Continuity (1)
Related Publication 20230218243A1 · Jul 13, 2023
References Cited (20)
US 8847166B2 · Fukuchi et al. · 2014 [cited by applicant]
US 9031303B2 · Yamaguchi · 2015 [cited by applicant]
US 20130334429A1 · Fukuchi et al. · 2013 [cited by applicant]
US 20140072200A1 · Yamaguchi · 2014 [cited by applicant]
US 20180239037A1 · Yamaya · 2018 [cited by examiner]
US 20190066342A1 · Zhu · 2019 [cited by examiner]
US 20190353808A1 · Watanabe · 2019 [cited by examiner]
US 20220334268A1 · Lee · 2022 [cited by examiner]
JP 2000028732A · 2000 [cited by applicant]
JP 2014052353A · 2014 [cited by applicant]
JP 2018136152A · 2018 [cited by applicant]
WO 2012077468A1 · 2012 [cited by applicant]
Apr. 27, 2021 International Search Report issued in Patent Application No. PCT/JP2021/008383. [cited by applicant]
Chinn, G. et al., “A method to include single photon events in image reconstruction for a 1 mm resolution PET system built with advanced 3-D positioning detectors.”, IEEE Nuclear Science Symposium Conference Record, (20… [cited by applicant]
Presentation slide of the relevant invention used at the World Molecular Imaging Congress 2019, Canada. [cited by applicant]
Abstract of the relevant invention published in the website of Springer Nature; (https://link.springer.com/article/10.1007/s11307-019-01453-z). [cited by applicant]
Presentation slide of the relevant invention used at the IEEE Nuclear Science Symposium (NSS) and Medical Imaging Conference 2019, England. [cited by applicant]
Abstract of the relevant invention published in the website of IEEE;(https://www.eventclass.org/contxt_ieee2019/online-program/session?s=MIC-19). [cited by applicant]
Presentation slide of the relevant invention used at the PET Imaging Physics Research Society 2020, JAPAN. [cited by applicant]
Report which the relevant invention was published in the 2019 report on PET Imaging Physics Research, Japan. [cited by applicant]
Cited By (1)
US 12,638,604