IP Library Granted Patent US 12,437,862
Granted Patent B2
US 12,437,862 · App. 17/763,622 · Granted Oct 7, 2025

Rare instance analytics for diversion detection

Inventors: Cynthia Yamaga (Oceanside, CA); Hien-Hoa Vu (Pearland, TX); Abhikesh Nag (San Diego, CA); Satya Varaprasad Allumallu (San Diego, CA); Dennis Tribble (Ormond Beach, FL)
Assignee: CareFusion 303, Inc.
G16H40/20G16H20/10
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Quick Facts
Patent No.
US 12,437,862
App. No.
17/763,622
Granted
Oct 7, 2025
Kind
B2
Abstract

A method for detecting diversion may include identifying an activity pattern associated with a clinician as being an infrequent activity pattern that occurs below a threshold frequency. Whether the infrequent activity pattern corresponds to an anomalous behavior may be determined based at least on one or more data models. The infrequent activity pattern may include a series of transaction records, which may be matched to the reference transaction values included in each of the one or more data models. An investigative workflow may be triggered in response to the infrequent activity pattern being determined to correspond to the anomalous behavior. Related methods and articles of manufacture are also disclosed.

Claims (34)

1. A system, comprising:

at least one data processor; and

at least one memory storing instructions which, when executed by the at least one data processor, result in operations comprising:

identifying an activity pattern associated with a first clinician as being an infrequent activity pattern that occurs below a threshold frequency, wherein the infrequent activity pattern is identified based at least on a signal-to-noise ratio associated with the infrequent activity pattern being below a threshold value;

determining, based at least on one or more data models, whether the infrequent activity pattern corresponds to an anomalous behavior;

triggering an investigative workflow in response to the infrequent activity pattern being determined to correspond to the anomalous behavior; and

causing a wasting station to provide a separate receptacle for unused medication from the first clinician, wherein the separate receptacle isolates the unused medication that the first clinician disposes of at the wasting station from a shared receptacle that comingles unused medication disposed by multiple clinicians.

2. The system of claim 1 , wherein the activity pattern includes a plurality of transaction records generated in response to the first clinician interacting with one or more data systems, and wherein the one or more data systems include an access control system, a dispensing system, an infusion system, a compounding system, and/or an electronic medical record system.

3. The system of claim 2 , wherein the plurality of transaction records include one or more transaction values corresponding to a timestamp, a patient identifier, a device identifier, a clinician identifier, a medication identifier, a prescription order identifier, an inventory information, a patient status, a shift identifier, a location tracking identifier, an infusion information, a compounding information, an administration information, a working off clock indicator, and/or an electronic health record identifier.

4. The system of claim 1 , wherein the one or more data models are generated based on a series of transaction records known to be associated with one or more types of anomalous behavior that are indicative of diversion.

5. The system of claim 4 , wherein each of the one or more data models include a combination of reference transaction values representative of a corresponding type of anomalous behavior, and wherein the combination of reference transaction values include one or more reference transaction values for the timestamp, the patient identifier, the device identifier, the clinician identifier, the medication identifier, the prescription order identifier, the inventory information, the patient status, the shift identifier, the location tracking identifier, the infusion information, the compounding information, the administration information, the working off clock indicator, and/or the electronic health record identifier.

6. The system of claim 1 , wherein the anomalous behavior includes the first clinician routinely selecting a second clinician to witness a wasting of medication while the second clinician also serves as a witness for a third clinician wasting medication.

7. The system of claim 1 , wherein the anomalous behavior includes the first clinician routinely selecting a second clinician to witness a wasting of medication and the second clinician routinely selecting the first clinician to witness the wasting of medication.

8. The system of claim 1 , wherein the anomalous behavior includes the first clinician withdrawing a medication for a deceased patient and/or a discharged patient.

9. The system of claim 1 , wherein the anomalous behavior includes the first clinician routinely accessing a medical management device within a threshold quantity of time after another clinician.

10. The system of claim 1 , wherein the anomalous behavior includes a paired cancellation of transactions, an unexpected forced opening of a medication management device, a clinician interacting with the medication management device when the clinician not scheduled to work, the clinician interacting with the medication management device when the clinician is not clocked in to for work, and/or the clinician interacting with the medication management device at an abnormal time.

11. The system of claim 1 , wherein the investigative workflow includes sending, to a client device, an alert indicating the first clinician as exhibiting the anomalous behavior.

12. The system of claim 1 , wherein the investigative workflow includes activating one or more surveillance devices in response to the first clinician interacting with a medical management device and/or isolating a medication accessed by the first clinician.

13. The system of claim 1 , wherein the infrequent activity pattern is determined to correspond to the anomalous behavior in response to a match between a first plurality of transaction values forming the infrequent activity pattern and a second plurality of reference transaction values included in a data model of the anomalous behavior being above a threshold value.

14. The system of claim 13 , wherein the threshold value is adjusted in response to a misidentification of more than a threshold quantity of infrequent activity patterns.

15. A computer-implemented method, comprising:

identifying an activity pattern associated with a first clinician as being an infrequent activity pattern that occurs below a threshold frequency, wherein the infrequent activity pattern is identified based at least on a signal-to-noise ratio associated with the infrequent activity pattern being below a threshold value;

determining, based at least on one or more data models, whether the infrequent activity pattern corresponds to an anomalous behavior;

triggering an investigative workflow in response to the infrequent activity pattern being determined to correspond to the anomalous behavior; and

causing a wasting station to provide a separate receptacle for unused medication from the first clinician, wherein the separate receptacle isolates the unused medication that the first clinician disposes of at the wasting station from a shared receptacle that comingles unused medication disposed by multiple clinicians.

16. The method of claim 15 , wherein the activity pattern includes a plurality of transaction records generated in response to the first clinician interacting with one or more data systems, and wherein the one or more data systems include an access control system, a dispensing system, an infusion system, a compounding system, and/or an electronic medical record system.

17. The method of claim 16 , wherein the plurality of transaction records include one or more transaction values corresponding to a timestamp, a patient identifier, a device identifier, a clinician identifier, a medication identifier, a prescription order identifier, an inventory information, a patient status, a shift identifier, a location tracking identifier, an infusion information, a compounding information, an administration information, a working off clock indicator, and/or an electronic health record identifier.

18. The method of claim 15 , wherein the one or more data models are generated based on a series of transaction records known to be associated with one or more types of anomalous behavior that are indicative of diversion.

19. The method of claim 18 , wherein each of the one or more data models include a combination of reference transaction values representative of a corresponding type of anomalous behavior, and wherein the combination of reference transaction values include one or more reference transaction values for the timestamp, the patient identifier, the device identifier, the clinician identifier, the medication identifier, the prescription order identifier, the inventory information, the patient status, the shift identifier, the location tracking identifier, the infusion information, the compounding information, the administration information, the working off clock indicator, and/or the electronic health record identifier.

20. A non-transitory computer readable medium storing instructions, which when executed by at least one data processor, result in operations comprising:

identifying an activity pattern associated with a clinician as being an infrequent activity pattern that occurs below a threshold frequency, wherein the infrequent activity pattern is identified based at least on a signal-to-noise ratio associated with the infrequent activity pattern being below a threshold value;

determining, based at least on one or more data models, whether the infrequent activity pattern corresponds to an anomalous behavior;

triggering an investigative workflow in response to the infrequent activity pattern being determined to correspond to the anomalous behavior; and

causing a wasting station to provide a separate receptacle for unused medication from the first clinician, wherein the separate receptacle isolates the unused medication that the first clinician disposes of at the wasting station from a shared receptacle that comingles unused medication disposed by multiple clinicians.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2022
From: YAMAGA, CYNTHIA; VU, HIEN-HOA; NAG, ABHIKESH; ALLUMALLU, SATYA VARAPRASAD; TRIBBLE, DENNIS
To: CAREFUSION 303, INC.
Reel/Frame 059405/0061 →
Continuity (2)
Provisional Application 62907295 · Sep 27, 2019
Related Publication 20220375581A1 · Nov 24, 2022
References Cited (206)
US 4551133A · Zegers de Beyl et al. · 1985 [cited by applicant]
US 4693804A · Serwer · 1987 [cited by applicant]
US 5945651A · Chorosinski et al. · 1999 [cited by applicant]
US 5961036A · Michael et al. · 1999 [cited by applicant]
US 5991731A · Colon et al. · 1999 [cited by applicant]
US 6113578A · Brown · 2000 [cited by applicant]
US 6650964B2 · Spano, Jr. et al. · 2003 [cited by applicant]
US 6671579B2 · Spano, Jr. et al. · 2003 [cited by applicant]
US 6842736B1 · Brzozowski · 2005 [cited by applicant]
US 6868344B1 · Nelson · 2005 [cited by applicant]
US 7119689B2 · Mallett et al. · 2006 [cited by applicant]
US 7184897B2 · Nelson · 2007 [cited by applicant]
US 7275645B2 · Mallett et al. · 2007 [cited by applicant]
US 7303081B2 · Mallett et al. · 2007 [cited by applicant]
US 7311207B2 · Mallett et al. · 2007 [cited by applicant]
US 7318529B2 · Mallett et al. · 2008 [cited by applicant]
US 7562025B2 · Mallett et al. · 2009 [cited by applicant]
US 7693603B2 · Higham · 2010 [cited by applicant]
US 8147479B1 · Wach et al. · 2012 [cited by applicant]
US 8195328B2 · Mallett et al. · 2012 [cited by applicant]
US 8280550B2 · Levy et al. · 2012 [cited by applicant]
US 8319669B2 · Weller · 2012 [cited by applicant]
US 8357114B2 · Poutiatine et al. · 2013 [cited by applicant]
US 8595021B2 · Mallett et al. · 2013 [cited by applicant]
US 8606596B1 · Bochenko et al. · 2013 [cited by applicant]
US 8725532B1 · Ringold · 2014 [cited by applicant]
US 8738177B2 · van Ooyen et al. · 2014 [cited by applicant]
US 8768724B2 · Whiddon et al. · 2014 [cited by applicant]
US 8905964B2 · Poutiatine et al. · 2014 [cited by applicant]
US 9056165B2 · Steil et al. · 2015 [cited by applicant]
US 9158892B2 · Levy et al. · 2015 [cited by applicant]
US 9202052B1 · Fang et al. · 2015 [cited by applicant]
US 9227025B2 · Butterfield et al. · 2016 [cited by applicant]
US 9354178B2 · Lee · 2016 [cited by applicant]
US 9427520B2 · Batch et al. · 2016 [cited by applicant]
US 9456958B2 · Reddy et al. · 2016 [cited by applicant]
US 9523635B2 · Tilden · 2016 [cited by applicant]
US 9636273B1 · Harris · 2017 [cited by applicant]
US 9752935B2 · Marquardt et al. · 2017 [cited by applicant]
US 9785744B2 · Johnson et al. · 2017 [cited by applicant]
US 9796526B2 · Smith et al. · 2017 [cited by applicant]
US 9817850B2 · Dubbels et al. · 2017 [cited by applicant]
US 9836485B2 · Dubbels et al. · 2017 [cited by applicant]
US 9842196B2 · Utech et al. · 2017 [cited by applicant]
US 9881129B1 · Cave · 2018 [cited by applicant]
US 9958324B1 · Marquardt et al. · 2018 [cited by applicant]
US 10032344B2 · Nelson et al. · 2018 [cited by applicant]
US 10101269B2 · Judge et al. · 2018 [cited by applicant]
US 10187288B2 · Parker et al. · 2019 [cited by applicant]
US 10209176B2 · Proskurowski et al. · 2019 [cited by applicant]
US 10241038B2 · Nishimura et al. · 2019 [cited by applicant]
US 10249153B2 · Nelson et al. · 2019 [cited by applicant]
US 10309832B2 · Marquardt et al. · 2019 [cited by applicant]
US 10345242B2 · Zhao et al. · 2019 [cited by applicant]
US 10569015B2 · Estes · 2020 [cited by applicant]
US 10580525B2 · Adams et al. · 2020 [cited by applicant]
US 10832207B2 · Vahlberg et al. · 2020 [cited by applicant]
US 11037666B1 · Benoit et al. · 2021 [cited by applicant]
US 11116892B2 · Brady et al. · 2021 [cited by applicant]
US 11147914B2 · Estes · 2021 [cited by applicant]
US 11222721B2 · Nag et al. · 2022 [cited by applicant]
US 11481739B1 · McKinzie · 2022 [cited by applicant]
US 20030158751A1 · Suresh et al. · 2003 [cited by applicant]
US 20030167190A1 · Rincavage et al. · 2003 [cited by applicant]
US 20050277873A1 · Stewart et al. · 2005 [cited by applicant]
US 20060064053A1 · Bollish et al. · 2006 [cited by applicant]
US 20070260487A1 · Bartfeld et al. · 2007 [cited by applicant]
US 20080059226A1 · Melker et al. · 2008 [cited by applicant]
US 20080082360A1 · Bailey et al. · 2008 [cited by applicant]
US 20080140715A1 · Hakos · 2008 [cited by applicant]
US 20080243055A1 · Fathallah et al. · 2008 [cited by applicant]
US 20080288430A1 · Friedlander et al. · 2008 [cited by applicant]
US 20080306796A1 · Zimmerman et al. · 2008 [cited by applicant]
US 20080319795A1 · Poteet et al. · 2008 [cited by applicant]
US 20090083231A1 · Eberholst et al. · 2009 [cited by applicant]
US 20090160646A1 · Mackenzie et al. · 2009 [cited by applicant]
US 20100169063A1 · Yudkovitch et al. · 2010 [cited by applicant]
US 20100213250A1 · Mallett et al. · 2010 [cited by applicant]
US 20100271218A1 · Hoag et al. · 2010 [cited by applicant]
US 20110016110A1 · Egi et al. · 2011 [cited by applicant]
US 20110082440A1 · Kimmo et al. · 2011 [cited by applicant]
US 20110161108A1 · Miller et al. · 2011 [cited by applicant]
US 20120173440A1 · Dehlinger et al. · 2012 [cited by applicant]
US 20120226447A1 · Nelson et al. · 2012 [cited by applicant]
US 20120265336A1 · Mallett et al. · 2012 [cited by applicant]
US 20120305132A1 · Maness · 2012 [cited by applicant]
US 20120325330A1 · Prince et al. · 2012 [cited by applicant]
US 20130002429A1 · Johnson · 2013 [cited by applicant]
US 20130018356A1 · Prince et al. · 2013 [cited by applicant]
US 20130070090A1 · Bufalini et al. · 2013 [cited by applicant]
US 20130144254A1 · Amirouche et al. · 2013 [cited by applicant]
US 20130253291A1 · Dixon et al. · 2013 [cited by applicant]
US 20130253700A1 · Carson et al. · 2013 [cited by applicant]
US 20130262138A1 · Jaskela et al. · 2013 [cited by applicant]
US 20130282392A1 · Wurm · 2013 [cited by applicant]
US 20130325727A1 · MacDonell et al. · 2013 [cited by applicant]
US 20140074284A1 · Czaplewski et al. · 2014 [cited by applicant]
US 20140081652A1 · Klindworth · 2014 [cited by applicant]
US 20140149131A1 · Bear et al. · 2014 [cited by applicant]
US 20140249776A1 · King et al. · 2014 [cited by applicant]
US 20140277707A1 · Akdogan et al. · 2014 [cited by applicant]
US 20140375324A1 · Matsiev et al. · 2014 [cited by applicant]
US 20150038898A1 · Palmer et al. · 2015 [cited by applicant]
US 20150061832A1 · Pavlovic et al. · 2015 [cited by applicant]
US 20150081324A1 · Adjaoute · 2015 [cited by applicant]
US 20150109437A1 · Yang et al. · 2015 [cited by applicant]
US 20150161558A1 · Gitchell et al. · 2015 [cited by applicant]
US 20150221086A1 · Bertram · 2015 [cited by applicant]
US 20150272825A1 · Lim et al. · 2015 [cited by applicant]
US 20150286783A1 · Kumar et al. · 2015 [cited by applicant]
US 20150294079A1 · Bergougnan · 2015 [cited by applicant]
US 20150323369A1 · Marquardt · 2015 [cited by applicant]
US 20150339456A1 · Sprintz · 2015 [cited by applicant]
US 20150362350A1 · Miller et al. · 2015 [cited by applicant]
US 20160034274A1 · Diao et al. · 2016 [cited by applicant]
US 20160062371A1 · Davidian et al. · 2016 [cited by applicant]
US 20160117478A1 · Hanina et al. · 2016 [cited by applicant]
US 20160161705A1 · Marquardt et al. · 2016 [cited by applicant]
US 20160166766A1 · Schuster et al. · 2016 [cited by applicant]
US 20160259904A1 · Wilson · 2016 [cited by applicant]
US 20160259911A1 · Koester · 2016 [cited by applicant]
US 20160283691A1 · Ali · 2016 [cited by applicant]
US 20160346469A1 · Shubinsky et al. · 2016 [cited by applicant]
US 20170017760A1 · Freese et al. · 2017 [cited by applicant]
US 20170032102A1 · Skoda · 2017 [cited by applicant]
US 20170076065A1 · Darr et al. · 2017 [cited by applicant]
US 20170083681A1 · Sprintz et al. · 2017 [cited by applicant]
US 20170103203A1 · Sharma et al. · 2017 [cited by applicant]
US 20170108480A1 · Clark et al. · 2017 [cited by applicant]
US 20170109480A1 · Vahlberg · 2017 [cited by examiner]
US 20170109497A1 · Tribble · 2017 [cited by examiner]
US 20170120035A1 · Butterfield et al. · 2017 [cited by applicant]
US 20170199983A1 · Cano et al. · 2017 [cited by applicant]
US 20180028408A1 · Li et al. · 2018 [cited by applicant]
US 20180039736A1 · Williams · 2018 [cited by applicant]
US 20180046651A1 · Dubbels et al. · 2018 [cited by applicant]
US 20180157803A1 · Mirov · 2018 [cited by applicant]
US 20180165417A1 · Hall et al. · 2018 [cited by applicant]
US 20180192942A1 · Clark et al. · 2018 [cited by applicant]
US 20180203978A1 · Basu et al. · 2018 [cited by applicant]
US 20180231415A1 · Marquardt et al. · 2018 [cited by applicant]
US 20180247703A1 · D'Amato · 2018 [cited by examiner]
US 20180259446A1 · Coffey et al. · 2018 [cited by applicant]
US 20180299375A1 · Young et al. · 2018 [cited by applicant]
US 20180330824A1 · Athey et al. · 2018 [cited by applicant]
US 20180365385A1 · Cooney et al. · 2018 [cited by applicant]
US 20180365386A1 · Vanderveen · 2018 [cited by applicant]
US 20190088354A1 · Yanowitz · 2019 [cited by examiner]
US 20190117883A1 · Abrams et al. · 2019 [cited by applicant]
US 20190124118A1 · Swafford · 2019 [cited by applicant]
US 20190139638A1 · Keefe et al. · 2019 [cited by applicant]
US 20190180862A1 · Wisser et al. · 2019 [cited by applicant]
US 20190244699A1 · Loebig et al. · 2019 [cited by applicant]
US 20190247703A1 · Welde et al. · 2019 [cited by applicant]
US 20190341142A1 · Nag et al. · 2019 [cited by applicant]
US 20190355461A1 · Kumar et al. · 2019 [cited by applicant]
US 20200085686A1 · Aliakbarian et al. · 2020 [cited by applicant]
US 20200098474A1 · Vanderveen · 2020 [cited by applicant]
US 20200219611A1 · Nag et al. · 2020 [cited by applicant]
US 20200222627A1 · Guerra et al. · 2020 [cited by applicant]
US 20200230316A1 · Guerra et al. · 2020 [cited by applicant]
US 20200312442A1 · Hairr et al. · 2020 [cited by applicant]
US 20200402632A1 · van Schelven et al. · 2020 [cited by applicant]
US 20210005324A1 · Bostic et al. · 2021 [cited by applicant]
US 20210027259A1 · Burgess et al. · 2021 [cited by applicant]
US 20210133201A1 · Tribble et al. · 2021 [cited by applicant]
US 20210308385A1 · Nisha et al. · 2021 [cited by applicant]
US 20220005574A1 · Kühn · 2022 [cited by applicant]
US 20220062964A1 · VanDerWoude et al. · 2022 [cited by applicant]
US 20220093239A1 · Nag et al. · 2022 [cited by applicant]
US 20220254470A1 · Lafauci et al. · 2022 [cited by applicant]
AU 2017279693A1 · 2018 [cited by applicant]
AU 2018335288B2 · 2023 [cited by applicant]
CA 2561239C · 2010 [cited by applicant]
CA 2636115C · 2014 [cited by applicant]
CA 2848274C · 2016 [cited by applicant]
CN 106687960A · 2017 [cited by applicant]
CN 110265108A · 2019 [cited by applicant]
EP 1973593B1 · 2013 [cited by applicant]
EP 1593076B1 · 2019 [cited by applicant]
JP 2007304654A · 2007 [cited by applicant]
JP 2016517077A · 2016 [cited by applicant]
JP 2018181340A · 2018 [cited by applicant]
KR 1020140129141A · 2014 [cited by applicant]
WO WO2006034367A2 · 2006 [cited by applicant]
WO WO2010058796A1 · 2010 [cited by applicant]
WO WO2011014517A1 · 2011 [cited by applicant]
WO WO2011035277A1 · 2011 [cited by applicant]
WO WO2011039676A2 · 2011 [cited by applicant]
WO WO2014055925A1 · 2014 [cited by applicant]
WO WO2015187682A1 · 2015 [cited by applicant]
WO WO2019028004A1 · 2019 [cited by applicant]
WO WO2019031331A1 · 2019 [cited by applicant]
WO WO2020163465A1 · 2020 [cited by applicant]
WO WO2020206154A1 · 2020 [cited by applicant]
WO WO2020251962A1 · 2020 [cited by applicant]
Benjamin, X.C. et al. (2012). “Visual identification of medicine boxes using features matching.” [cited by applicant]
Cakaloglu, T. (Nov. 1, 2017). “Medi-Deep: Deep control in a medication usage.” [cited by applicant]
Neuman, M.R. et al. (May 13, 2012), “Advances in Medical Devices and Medical Electronics,” in Proceedings of the IEEE, vol. 100, No. Special Centennial Issue, pp. 1537-1550,doi: 10.1109/JPROC.2012.2190684. [cited by applicant]
Qui et al. (2016) “A survey of machine learning for big data processing.” [cited by applicant]
Shishvan, O. Rajabi et al. (2018). “Machine Intelligence in Healthcare and Medical Cyber Physical Systems: A Survey.” IEEE Access. vol. 6, 46419-46494. doi: 10.1109/ACCESS.2018.2866049. [cited by applicant]
Uniyal, D. et al. (Nov. 7, 2014), “Pervasive Healthcare—A Comprehensive Survey of Tools and Techniques,” arXiv:1411.1821v1, 48 pages. [cited by applicant]
Yang, J., Mcauley, J.J., & Leskovec, J. (2013). “Community Detection in Networks with Node Attributes.” 2013 IEEE 13th International Conference on Data Mining, 1151-1156. [cited by applicant]
Yaniv, Z. et al. (Oct. 1, 2016). “The National Library of Medicine Pill Image Recognition Challenge: An Initial Report.” [cited by applicant]
Zhan, A. et al. (Jan. 5, 2016) “High Frequency Remote Monitoring of Parkinson's Disease via Smartphone: Platform Overview and Medication Response Detection,” Retrieved Apr. 29, 2021. 12 pages. [cited by applicant]
Svendsen, K. et al. (2011). “Choosing the Unit of Measurement Counts: The Use of Oral Morphine Equivalents in Studies of Opioid Consumption Is a Useful Addition to Defined Daily Doses.” Palliative Medicine, vol. 25, No.… [cited by applicant]