IP Library › Granted Patent US 12,440,289
Granted Patent B2
US 12,440,289 · App. 18/060,935 · Granted Oct 14, 2025

Method of priming an interventional device assembly

Inventors: Lilip Lau (Los Altos, CA); Steven Meyer (Oakland, CA); Kyle Bartholomew (Campbell, CA); Craig Mar (Fremont, CA); Ian Peter Van Sciver (Tollhouse, CA)
Assignee: Imperative Care, Inc.
A61B34/30A61B2034/301A61M2005/1402A61M25/0113A61M2025/0681A61M25/09
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Quick Facts
Patent No.
US 12,440,289
App. No.
18/060,935
Granted
Oct 14, 2025
Kind
B2
Abstract

A method of priming an interventional device assembly includes providing the interventional device assembly, the interventional device assembly including a first interventional device and a second interventional device, the second interventional device being positioned within the first interventional device. The method further includes reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device while flushing a lumen between the first interventional device and the second interventional device with fluid to remove microbubbles from the lumen.

Claims (28)

1. A method of priming an interventional device assembly, comprising:

providing the interventional device assembly, the interventional device assembly comprising a first interventional device and a second interventional device, the second interventional device being positioned within the first interventional device; and

reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device while flushing a lumen between the first interventional device and the second interventional device with fluid to remove microbubbles from the lumen.

2. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device in response to a control signal.

3. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises reciprocally moving at least one of a first robotic drive coupled to the first interventional device and a second robotic drive coupled to the second interventional device relative to the other of the first robotic drive and the second robotic drive.

4. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device.

5. The method of claim 4 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device further comprises rotationally reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device.

6. The method of claim 4 , wherein axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device over a stroke length between about 10 mm and about 250 mm.

7. The method of claim 6 , wherein axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device over a stroke length between about 25 mm and about 125 mm.

8. The method of claim 4 , wherein axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device over a stroke length greater than 20 mm.

9. The method of claim 4 , wherein axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises axially reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device at a reciprocation frequency of no more than about 5 Hz.

10. The method of claim 9 , wherein the reciprocation frequency is no more than about 1 Hz.

11. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises rotationally reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device.

12. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device comprises reciprocally moving both the first interventional device and the second interventional device relative to one another.

13. The method of claim 1 , wherein reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device is performed by a robotic drive table.

14. The method of claim 1 , wherein the first interventional device is a first catheter and the second interventional device is a second catheter.

15. The method of claim 1 , wherein the first interventional device is a catheter and the second interventional device is a guidewire.

16. A method of priming a multi catheter assembly, comprising:

providing the multi catheter assembly, the multi catheter assembly comprising a guidewire, an access catheter, a procedure catheter, and a guide catheter arranged in a concentric catheter stack, wherein the guidewire is positioned within a lumen of the access catheter, the access catheter is positioned within a lumen of the procedure catheter, and the procedure catheter is positioned within a lumen of the guide catheter; and

flushing the guide catheter with saline while reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter.

17. The method of claim 16 , wherein flushing the guide catheter with saline while reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter comprises reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter in response to a control signal.

18. The method of claim 16 , wherein flushing the guide catheter with saline while reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter comprises reciprocally moving at least one of a first robotic drive coupled to the guide catheter and a second robotic drive coupled to the procedure catheter relative to the other of the first robotic drive and the second robotic drive.

19. The method of claim 16 , wherein flushing the guide catheter with saline while reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter comprises axially reciprocally moving, rotationally reciprocally moving, or both axially and rotationally reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter.

20. The method of claim 16 , further comprising flushing the procedure catheter with saline while reciprocally moving at least one of the procedure catheter and the access catheter relative to the other of the procedure catheter and the access catheter.

21. The method of claim 20 , wherein flushing the procedure catheter with saline while reciprocally moving at least one of the procedure catheter and the access catheter relative to the other of the procedure catheter and the access catheter comprises axially reciprocally moving, rotationally reciprocally moving, or both axially and rotationally reciprocally moving at least one of the procedure catheter and the access catheter relative to the other of the procedure catheter and the access catheter.

22. The method of claim 20 , further comprising flushing the access catheter with saline while reciprocally moving at least one of the access catheter and the guidewire relative to the other of the access catheter and the guidewire.

23. The method of claim 22 , wherein flushing the access catheter with saline while reciprocally moving at least one of the access catheter and the guidewire comprises axially reciprocally moving, rotationally reciprocally moving, or both axially and rotationally reciprocally moving at least one of the access catheter and the guidewire relative to the other of the access catheter and the guidewire.

24. The method of claim 22 , wherein the steps of flushing the guide catheter with saline while reciprocally moving at least one of the guide catheter and the procedure catheter relative to the other of the guide catheter and the procedure catheter, flushing the procedure catheter with saline while reciprocally moving at least one of the procedure catheter and the access catheter relative to the other of the procedure catheter and the access catheter, and flushing the access catheter with saline while reciprocally moving at least one of the access catheter and the guidewire relative to the other of the access catheter and the guidewire are performed simultaneously.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2025
From: LAU, LILIP; MEYER, STEVEN; BARTHOLOMEW, KYLE; MAR, CRAIG; VAN SCIVER, IAN PETER
To: IMPERATIVE CARE, INC.
Reel/Frame 071855/0226 →
Continuity (7)
Continuation In Part 17959894 · Oct 4, 2022
Continuation In Part 17960014 · Oct 4, 2022
Continuation In Part 17959924 · Oct 4, 2022
Continuation In Part 17816669 · Aug 1, 2022
Continuation In Part 17816669 · Aug 1, 2022
Continuation In Part 17816669 · Aug 1, 2022
Related Publication 20240033019A1 · Feb 1, 2024
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